Glossary extracted starting with manual seeds, with BOW for the domain bio and language EN

c.i.See confidence interval.
moleThe number of grams of a substance that equals its molecular weight in daltons and contains Avogadro's number of molecules.
methionine cycleThe cycling of methionine to SAM, homocysteine, and back to methionine.
hydroxylamineNH2OH
operational taxonomic unitOne of the organisms being compared in a phylogenetic analysis.
global warming potentialnumber that represents the relative contribution of a molecule of an atmospheric gas to global warming
dipoleA molecule having both positive and negative charges.
avogadro's numbernumber of atoms in exactly 12 g of carbon-12
dsdnaDouble-stranded DNA.
estivation(1) In mammals and birds, a form of controlled hypothermia in which the body temperature is able to approximate ambient temperature continuously for two or more consecutive days during summer
applied researchEngineering-type research that puts the discoveries of basic research into practice.
transpirationPassage of water from the roots of a plant to the atmosphere via the vascular system and the stomata of the leaves.
chemo-autotrophA microorganism that obtains energy from light-independent inorganic reactions.
mutesilent: without power to produce audible sound.
ascorbic acidAnother name for vitamin C, a compound with antioxidant properties that may help protect nerve cells from free radical damage and glutamate toxicity.
skeletonSupport structure in animals, against which the force of muscles acts
foldingThe acquisition of 3-D structure by a protein; the pattern of the 3-D structure that is the result of the folding process.
compoundA substance formed by two or more elements
long-day plantA plant that flowers (usually in late spring or early summer) only when the light period is longer than a critical length.
climateThe long-term prevailing weather in an area that is largely determined by temperature and precipitation.
antibioticA natural product that inhibits bacterial growth (is bacteriostatic) and sometimes results in bacterial death (is bacteriocidal).
chemical fingerprintingThe analysis of low molecular weight components of a cell by techniques, such as mass spectrometry, gas chromatography, and HPLC.
soluteA substance that is dissolved in a solution.
calorieThe amount of energy necessary to raise the temperature of 1,000 grams of water by 1°C
micro chemical systemA miniature system for the synthesis and analysis of chemicals.
carrying capacityThe maximum population size that can be supported by the available resources, symbolized as K.
anaerobic bacteriabacteria that can function without the use of molecular oxygen
correlationDegree of association between two or more variables.
arrayed libraryTwo-dimensional arrays of recombinant clones
nitrogen cycleThe passage of nitrogen through various valence states, as the result of reactions carried out by a wide variety of different organisms.
detritusAccumulated organic debris from dead organisms, often an important source of nutrients in a food web.
hydrophobicHaving an aversion to water; tending to coalesce and form droplets in water.
sampling errorDeviations from expected ratios due to chance occurrences when the number of events is small.
fiordA steep-sided, drowned coastal valley carved by glacial action
cis-displacementMovement of a nucleosome to a new position on a DNA molecule.
albedoratio of electromagnetic radiation reflected relative to the amount of radiation incident on a surface
phytoplanktonAlgae and photosynthetic bacteria that drift passively in the peJagic zone of an aquatic environment.
synchronoushappening at the same time.
locomotionActive movement from place to place.
transpirationThe evaporative loss of water from a plant
chaparralA scrubland biome of dense, spiny evergreen shrubs found at midlatitudes along coasts where cold ocean currents circulate offshore; characterized by mild, rainy winters and long, hot, dry summers.
integrationThe coordination of input signals, as by summing, to provide a harmonious control of output
neutronAn electrically neutral particle (a particle having no electrical charge), found in the nucleus of an atom.
trophic structureThe different feeding relationships in an ecosystem, which determine the route of energy flow and the pattern of chemical cycling.
convectionThe mass movement of warmed air or liquid to or from the surface of a body or object.
tgaseAn abbreviation for transglutaminase.
moleOne gram molecular weight of a compound
nitrogen cycleThe cycling of various forms of biologically available nitrogen through the plant, animal, and microbial worlds, and through the atmosphere and geosphere.
ketogenic amino acidsAmino acids with carbon skeletons that can serve as precursors of the ketone bodies.
ventilation-perfusion matchingIn a breathing organ, matching of the rate of blood flow and the rate of ventilation so that efficiency is promoted in the transfer of O2 from air or water to the blood.
immunizationThe process of generating a state of immunity by artifical means
heat shock responseA mechanism cells use to maintain stability when subjected to stress
allometric equationsAn equation to aid in the calculation of the change in proportion of various parts of an organism as a consequence of growth.
circadian rhythmAn endogenous rhythm with a period of about a day (ca
saturated hydrocarbonhydrocarbon chain containing only single bonds between the carbon atoms
submaximal exerciseExercise that requires less than an individual’s maximal rate of O2 consumption.
phytoalexinA type of compound produced by some plants in response to fungal infection or injury
pest sequencesAmino acid sequences that influence the degradation of proteins in which they are found.
psychopathyA condition characterized by the inability to connect to other people normally
reciprocal recombinationA precise exchange of genetic information like that expected for a simple cut, exchange, and rejoin mechanism
ink-jet technologyA non-contact method for delivering biomolecules to substrate surfaces
wavelengthThe distance between crests of waves, such as those of the electromagnetic spectrum.
microdissectionDissection of organisms by mechanically controlled instruments monitored using a microscope.
mass numberThe sum of the number of protons and neutrons in an atom's nucleus.
phosphogluconate pathwayAnother name for the pentose phosphate pathway
protein drugSee therapeutic agent.
control rodsrods composed primarily of an excellent neutron absorber such as cadmium or boron that can be positioned in a nuclear reactor to absorb fewer or more neutrons, thereby regulating the rate of fission
nucleoside analogSee analog.
soluble proteinSee globular protein.
polar stratospheric cloudsthin stratospheric clouds composed of a small amount of frozen water vapor
in situin its natural place or normal position.
parts per billion1 part out of a billion parts, unit of concentration
cross-flow filtrationA technique for filtering thick fluids by flowing the fluid across the filter
open systemA defined part of the material universe that is not isolated, meaning that it is capable of exchanging matter, energy, or both with its surroundings.
hydronium ionwater molecule plus a proton
live cell arrayA micro-system for the high-throughput analysis of intact cells.
biophotonicsBiological applications of photonics, a technology that utilizes light and other forms of radiant energy in which a quantum unit is the photon.
hydrofluorocarbonscompounds of hydrogen, fluorine, and carbon
stssee Sequence tagged site.
curated databaseA database developed by a curator with domain expertise
laAbbreviation for linoleic acid.
parametersUser-derived values used to set the boundaries of an algorithm.
lithotrophA microorganism that synthesizes all organic molecules from inorganic sources.
plasmogamyA process of fusion of the cytoplasm of two cells; the first step in syngamy.
punctuated equilibriumIn evolutionary theory, long periods of apparent stasis (no change) interrupted by relatively brief periods of sudden change.
lipoxygenaseAn enzyme that plays a pivotal role in the synthesis of inflammatory mediators known as leukotrienes.
crepitationa crackling sound or the production of such as by discharge of vapor or "bombarding": a cracking or creaking.
ginkgo bilobaA plant that has been shown to have certain antioxidant, anti-inflammatory, and neuroprotective properties
pinnaa narrow wing; a feather.
agarose gel electrophoresisElectrophoresis carried out in an agarose gel and used to separate DNA molecules between 100 bp and 50 kb in length.
beta waveA type of brain wave; occurs during times of active thinking.
amyloidAnother term for beta-amyloid
pha number, usually between 0 and 14, that indicates the acidity of a solution
perturbagenA molecule or peptide that disrupts intracellular processes, providing information about the operation of pathways and networks within the cell.
solutionA liquid that is a homogeneous mixture of two or more substances.
polarA hydrophilic (water-loving) chemical group.
photic zoneThe narrow top slice of the ocean, where light permeates sufficiently for photosynthesis to occur.
dose responseA relationship in which a change in the amount, intensity, or duration of an exposure is associated with either an increase or decrease in risk of a specified health outcome.
chelatorA molecule that binds metal ions.
bufferA solution containing agents that maintain a constant pH during a biochemical reaction.
basal ganglionSingular form of basal ganglia.
micromanipulatorInstrument used with a microscope for manipulating small instruments and specimens.
zetta-A prefix indicating 1021; a sextillion.
geometric isomersIsomers related by rotation about a double bond; also called cis and trans isomers.
markovian modelAlternate name for a Markovian chain in which a sequence of random events where the current state solely depends on the previous state.
hydrophobic interactionsThe association of nonpolar groups, or compounds, with each other in aqueous systems, driven by the tendency of the surrounding water molecules to seek their most stable (disordered) state.
polyacrylamide gel electrophoresisSee PAGE.
fasciaa transverse band or broad line; it is common when it crosses both wings or wing covers.
cross resistanceThe condition in which resistance to one pesticide or antibiotic confers increased resistance to a second pesticide or antibiotic.
sedimentation analysisThe centrifugal technique used to measure the sedimentation coefficient of a molecule or structure.
caprificationis that method or process through which the Smyrna figs are fertilized by Blastophaga throughthe medium of wild, inedible or "caprifigs."
compoundA substance consisting of two or more elements in a fixed ratio.
t cellA T-lymphocyte.
biosphereAll the living matter on or in the earth, the seas, and the atmosphere.
fatty acidA long carbon chain carboxylic acid
temperatureA measure of the intensity of heat in degrees, reflecting the average kinetic energy of the molecules.
radioactive markerA radioactive atom incorporated into a molecule and whose radioactive emissions are subsequently used to detect and follow that molecule during a biochemical reaction.
erecto-patentthe wings of Hesperids when at rest; primaries erect, secondaries horizontal.
microfluidics chipsThe chips contain very tiny channels in which the movement of fluids can be controlled
dntpAbbreviation for a deoxynucleoside 5'-triphosphate when the exact deoxynucleotide (typically dATP, dTTP, dGTP, or dCTP) is unspecified or unknown.
seedless vascular plantsThe informal collective name for the phyla Lycophyta (club mosses and their relatives) and Pteridophyta (ferns and their relatives).
molecular modelingComputational analysis and modeling of the physicochemical properties of a molecule or biomacromolecule.
muscular systemThe muscular system is the biological system of animals that allows them to move internally and externally.
borealArea located in northern latitudes, between the tundra and the temperate forest, mostly from 52 degrees N to 66 degrees N.
x-ray crystallographyA technique that depends on the diffraction of an X-ray beam by the individual atoms of a molecule to study the three-dimensional structure of the molecule.
random primersA set of short oligonucleotides with variable sequences
prominentraised or produced beyond the level or margin: standing out in relief by color or otherwise: conspicuous.
chemical shiftThe change in the rotation of a chemical nucleus, used as the basis of NMR.
equilibriumA state of balance in which there is no net change.
nitrogen fixationConversion of atmospheric nitrogen into a form that can be converted by biochemical reactions to an organic form
tera-A prefix indicating 10 to the power of 12; a trillion.
cystamineA TGase inhibitor shown to be a potential treatment for HD.
pfgeSee Pulsed field gel electrophoresis.
hicks' bottles{Scanner's comment: sic} flask-shaped pits or depressions in the antennae of bees and ants: supposed to be the organs of hearing.
resolutionSeparation of a pair of recombining double-stranded DNA molecules.
orderone of the primary divisions of the Class Insecta, based largely on wing structure and then usually ending in -ptera.
grasslandRegion in which the climate is dry for long periods of the summer, and freezes in the winter
eluateThe fluid that has passed through (eluted from) a chromatographic column.
scoreTo determine the presence or absence of a phenotype by testing for growth under different conditions (e.g., plus and minus an auxotrophic supplement or permissive and nonpermissive conditions)
energy trappingThe capture of energy released in one reaction for use in a second reaction.
steady state kineticsThe analysis of an enzyme reaction during the interval when the concentration of intermediates is steady.
moderatormaterial that slows the neutrons in a nuclear reactor, making them more effective in producing fission
frontal tuberclesin certain Aphids, are raised structures upon which the antennae are placed.
post-replication repairA DNA repair process which occurs after DNA replication.
trace elementAn element indispensable for life but required in extremely minute amounts.
tidal flowFlow that occurs alternately in and out through a single set of passageways.
neuropsychiatristA physician who treats people with psychiatric symptoms that are caused by a brain disorder
segmentationOne of the gut’s principal modes of muscular activity, in which circular muscles contract and relax in patterns that push the gut contents back and forth.
isoenzymesSee isozymes.
antigenSubstance that is recognized by the immune system and elicits an immune response.
cohesionThe force that holds molecules of the same substance together.
absorption spectrumThe range of a pigment's ability to absorb various wavelengths of light.
implantSee implantation.
humidityA general term referring loosely to the concentration of gaseous water in a gas
petri dishFlat round dish with a matching lid, made of glass or plastic material, and used for culturing organisms
stefan-boltzmann equationAn equation that relates the temperature of a surface and the rate at which the surface emits electromagnetic energy.
multiplication ruleStates that the probability of two or more independent events occurring together is calculated by multiplying the probabilities of each of the individual events.
ozone layerA layer of ozone around the earth protects the life on earth from the sun.s harmful ultraviolet rays
population ecologyThe study of individual populations (of a single species), including their birth, death, and growth rates in numbers and their growth rates of individual mass and population biomass; also includes their spatial distributions and rates of movement (immigration, emigration).
crAbbreviation for creatine.
polarimeterAn instrument for determining the rotation of polarization of light as the light passes through a solution containing an optically-active substance.
ionAn atom that has gained or lost electrons, thus acquiring a charge.
denaturationA change in the tertiary (three-dimensional) structure of an intact protein that renders the protein nonfunctional
ambystoma mexicanumMexican axolotl (amphibian)
non-composite transposonA transposible element that is NOT flanked by IS elements.
respirationGeneral term for any cellular process involving the uptake of O2 coupled to production of CO2.
oxidoreductaseA class of enzymes that catalyse oxidoreduction reactions which transfer electrons from a hydrogen donor to a hydrogen acceptor.
anadromousRelating to an aquatic animal that undergoes most of its growth in seawater but enters freshwater to breed.
competitive inhibitorA substance that reduces the activity of an enzyme by entering the active site in place of the substrate whose structure it mimics.
local regulatorA chemical messenger that influences cells in the vicinity.
chlorophyllthe green coloring matter of plants; one of the substances found in the blood of insects.
intervalthe space or time between two structures, sculptures or periods of development.
footprintingA method for identification of a protein-binding site on a DNA molecule
wavelengthFor light or sound, or other wave, the distance between one crest of the wave to the next crest
cloneAn exact copy of a
curieunit of radioactivity, equal to 3.7 ×1010 disintegrations/s and roughly equivalent to the level of radioactivity from 1 g of radium
hydrolysisthe chemical decomposition of a compound by water, causing formation of a new compound.
perennialA plant which continues to grow after it has reproduced, usually meaning that it lives for several years.
heuristic algorithmA programming strategy based on trial-and-error methods and feedback evaluation.
chromophoreA functional group that absorbs light, giving rise to color.
nodeA point along the stem of a plant at which leaves are attached.
uniformitarianismCharles Lyell's idea that geologic processes have not changed throughout Earth's history.
amino acidunit molecule from which proteins are constructed by polymerization.
concentration gradientTechnically, the difference in the concentration of a solute between two places divided by the distance separating those two places
radial symmetrycharacterizing a body shaped like a pie or barrel, with many equal parts radiating outward like the spokes of a wheel; present in cnidarians and echinoderms
isomerOne of several organic compounds with the same molecular formula but different structures and therefore different properties
climate changeChanges in intensity and distribution of solar radiation reaching Earth.s surface.
antioxidantA molecule that is capable of reacting with free radicals and neutralizing them.
iptgAn abbreviation for isopropyl-ß-D-thiogalactoside
pipettingUsing a pipette (a syringe-like instrument) to measure and transfer liquids from one container to another.
osmoregulationHow organisms regulate solute concentrations and balance the gain and loss of water.
nsaidsAbbreviation for nonsteroidal anti-inflammatory drugs.
troposphereregion of the atmosphere that lies directly above the surface of the Earth
chromatographyThe separation of a mixture of substances by charge, size, or other property by allowing the mixture to partition between a moving phase and a stationary phase.
protonophoreAn ionophore that transports protons.
maximum contaminant levellegal limit for the concentration of a contaminant
lateral rootA root that arises from the outermost layer of the pericycle of an established root.
teleologyThe belief that natural events and objects have purposes and can be explained by their purposes.
ozone layerregion of the stratosphere with the maximum ozone concentration
standard deviationThe square root of the variance.
microgramA measurement of mass; commonly used in measuring dietary supplements (1 mcg= 10^-6 grams).
recombinationThe process by which progeny derive a combination of 
nuclear inclusionsAnother term for neuronal inclusions.
drug deliveryThe delivery of a drug to the site of action
photoautotrophAn organism that harnesses light energy to drive the synthesis of organic compounds from carbon dioxide.
atomoxetineThe first non-stimulant drug approved for the treatment of ADHD
enzymeA protein that triggers or "catalyzes" a biochemical reaction.
mesosphereregion of the atmosphere above the stratosphere; found at an altitude starting about 50 km
phase variationA mechanism which results in variable expression of surface antigens
microclimateThe set of climatic conditions (temperature, humidity, wind speed, and so forth) prevailing in a subpart of a larger environmental system.
hill reactionThe evolution of oxygen and the photoreduction of an artificial electron acceptor by a chloroplast preparation in the absence of carbon dioxide.
neotropicalthat part of the earth's surface embraced in the greater part of Mexico, West Indies and South America.
high field nmrA high-resolution NMR method based on higher field magnets that enables the analysis of large molecules.
poiseuille equationAn equation that describes the quantitative relation between the rate of flow of fluid through a horizontal tube and factors such as pressure, luminal radius, and length
xenopus laevisAn African clawed toad used to study developmental biology.
metazoona multicellular animal as opposed to a unicellular protozoon.
cathodeelectrode where reduction takes place
pheromoneA hormone-like substance that acts as an attractant.
tidal volumeThe volume of air an animal inhales and exhales with each breath.
adhesionThe tendency of unlike substances to stick together
antibioticA substance usually produced by a fungus or bacteria that can kill other microorganisms
rootAn organ in vascular plants that anchors the plant and enables it to absorb water and nutrients from the soil.
rate constantThe rate constant is the proportionality factor that appears in mass-action rate laws
dehydrogenaseAn enzyme that catalyzes the removal of a pair of electrons (and usually one or two protons) from a substrate molecule.
unequal crossing over modelA possible model for how repeat expansions occur
amyloid fibrilsAnother term for beta-amyloid fibrils.
culture mediumA liquid or gel-like substance containing nutrients in which tissues are cultivated for scientific purposes; used in tissue culture.
fastaAn algorithm for identifying sequence similarities.
aldehydeA molecule containing a doubly bonded oxygen and a hydrogen attached to the same carbon atom.
sirtuinsA group of enzymes that may play a role in lifespan extension.
kineticsThe study of the rate of change.
tertileThis term is often used in explaining the distribution of scores on a test
translocationThe movement of organic compounds , especially sucrose, through a plant by means of the phloem tissue.
genetic information nondiscrimination actA federal law will protect Americans against discrimination based on their genetic information when it comes to health insurance and employment.
nonheme iron proteinsProteins, usually acting in oxidation-reduction reactions, containing iron but no porphyrin groups.
replicationThe process of duplicating a DNA molecule.
hydrophobic moleculeA nonpolar compound that does not form favorable binding interactions with water, and is insoluble in water.
sedimentAny solid material that has settled out of a state of suspension in liquid.
trace mineralsminerals in the diet that are usually required in micrograms
ultracentrifugeA high-speed centrifuge that can attain speeds up to 60,000 rpm and centrifugal fields of 500,000 times gravity
radio-carbon datingMethod for determining the age of an organic substance by measuring the amount of the carbon isotope, carbon-14, remaining in the substance; useful for determining ages in the range of 500 to 70,000 years.
transport epitheliumOne or more layers of specialized epithelial cells that regulate solute movements.
horna pointed chitinous process of the head: in the plural form applied to the antennae; q.v.
hypothesisA tentative explanation for an observation, phenomenon, or scientific problem that can be tested by further investigation.
plasticAble to be shaped or changed.
gigabase pair1 000 000 kb; 1 000 000 000 bp.
microcellvery tiny fuel cell
isochromosomean abnormal symmetrical chromosome, consisting of two identical arms, which are normally either the short arm or the long arm of a normal chromosome.
continuous charactera character like height, which everybody has, but to a differing degree – as compared to a dichotomous character like polydactyly, which some people have and others do not have.
dissociation curveA chart showing the relative amounts of oxygen bound to hemoglobin when the pigment is exposed to solutions varying in their partial pressure of dissolved oxygen, pH, or other characteristics.
exotoxinA toxin released by a microbe.
molecular weightSee Gram molecular weight.
computer-assisted drug designComputational techniques to design and optimize biologically active compounds with desired structure and properties.
cohesionThe force that holds molecules of the same substance together
emergentDescribes a property of a system that is not predictable from the starting conditions.
first principle molecular dynamicsThe use of quantum chemical interactions to simulate the motion of molecules.
noble gaseselements that are inert and do not readily undergo chemical reactions
pharmacologicalpharmacological research involves studing how chemicals interact with living organisms
hdac inhibitorsAbbreviation for histone deacetylase inhibitors.
x-ray crystallographyA technique for determining the structure of molecules from the X-ray diffraction patterns that are produced by crystalline arrays of the molecules.
positive feedbackA physiological control mechanism in which a change in some variable triggers mechanisms that amplify the change.ex
spotted arrayArray generated by microspotting nucleic acids on a glass, plastic, or filter substrate.
photosynthetic efficiencyEfficiency of converting light energy into organic compounds.
neuronal intranuclear inclusionsAnother term for neuronal inclusions.
quencherA substance that deactivates excited molecules by processes such as resonance energy transfer and complex formation.
recursionThe repetition of a data-processing algorithm until a pre-set threshold is reached.
second law of thermodynamicsThe second law says that no process is 100% efficient because heat is always produced
thermal crackingheating of starting materials to a high temperature
vaporizationA change in the physical state of a material from a liquid to a gas.
xylemVascular plant tissue consisting mainly of tubular dead cells that conduct most of the water and minerals upward from roots to the rest of the plant.
charactera quality of form, color or structure.
synergistAn agent that increases the effectiveness of a ligand or other agent.
covarianceA measure of how much two variables change together.
molecular phylogeneticsA set of techniques that enable the evolutionary relationships between DNA sequences to be inferred by making comparisons between those sequences.
saturated fatty acidA fatty acid in which all carbons in the hydrocarbon tail are connected by single bonds, thus maximizing the number of hydrogen atoms that can attach to the carbon skeleton.
continuous charactera character like height, which everybody has, but to a differing degree – as compared to a dichotomous character
institutional review boardAn IRB is an independent ethics committee for an institution that serves to approve, monitor, and review biomedical and behavioral research involving humans with the aim to protect the rights and welfare of the subjects.
ecological successionTransition in the species composition of a biological community, often following ecological disturbance of the community; the establishment of a biological community in an area virtually barren of life.
randomizedIn the context of a clinical trial, randomized refers to how the different treatments (either the potential drug or the standard treatment) are allocated to the trial subjects
postsynapticLiterally "after the synapse;" a structure or event that occurs after small gaps between nerve cells
x-ray crystallographyA technique for determining the 3-D structure of a molecule, based on the diffraction of x-rays by the crystallized form of the molecule
fertilizationFusion of gametes, or sex cells, to form a zygote.
carbohydrateA polyhydroxy aldehyde or ketone.
association constantThe measure of the degree of association of a complex
pratinicolousfrequenting or living in grassy meadows or bogs.
metadataInformation about data that facilitates access and use of the data.
magnetic reversalA reversal of the polarity of Earth's magnetic field.
wavenumbersnumbers often expressed in units of cm-1 and used on the x-axis of an infrared spectrum; inversely proportional to wavelength
cell wallA tough outer coating found in many plant, fungal, and bacterial cells that accounts for their ability to withstand mechanical stress or abrupt changes in osmotic pressure
polyacrylamide gelsOften referred to incorrectly as acrylamide gels
dihybrid crossA sexual cross in which the inheritance of two pairs of alleles is followed.
cytochrome oxidase complexAnother term for Complex IV.
linear regressionA statistical technique of finding the best fitting straight line through a set of points representing joint values for two variables.
tfcSee total functional capacity.
nf-kbAbbreviation for NF-kappa B.
linking numberThe net number of times one polynucleotide chain crosses over another polynucleotide chain
join point.The site where two DNA molecules are connected
filter matingA method where conjugation between donor and recipient bacteria is done on a millipore filter
ideal gas lawSee universal gas law.
disturbanceA force that changes a biological community and usually removes organisms from it
excimerAn adduct between a molecule that has been excited by a photon and a second molecule.
fungicidalThe ability to kill fungi
phospho-diester bondA bond in which a phosphate group joins adjacent carbons through ester linkages
dissociation constantThe dissociation constant () is the equilibrium constant for the dissociation of a complex into its component parts
hsf-1Abbreviation for heat shock factor 1.
primera short oligonucleotide, often 15–25 bases long, which base-pairs specifically to a target sequence to allow a polymerase to initiate synthesis of a complementary strand
densitythe ratio of mass per unit volume
henderson-hasselbalch equationAn equation that relates the pKa, to the pH and the ratio of the proton acceptor (A-) and the proton donor (HA) species of a conjugate acid base pair.
anodeelectrode where oxidation takes place
global atmospheric lifetimetime required for a gas added to the atmosphere to be removed
biotherapyTreatment with genetically engineered biological materials.
protein complexa group of two or more associated proteins that function together to perform a specific task or make a certain structure.
scavengeTo combine readily with free radicals, preventing them from reacting with other molecules.
robertsonian fusiona chromosomal rearrangement that converts two acrocentric chromosomes into one metacentric
adpAbbreviation for adenosine diphosphate.
simulation modelA model in which the relationships among the variables are programmed into a computer for analysis.
density-gradient centrifugationSeparation of molecules and particles on the basis of buoyant density, by centrifugation in a concentrated sucrose or caesium chloride solution.
pretest counselingCounseling offered to help individuals make informed decisions as to whether or not they should be genetically tested for HD
chemotaxisThe movement of a cell or organism in response to a chemical gradient.
snrnpAbbreviation for Small Ribonuclear Particle.
cellThe primary unit of physical life, whose integral structure and optimal status is crucial for the healthy functioning of the human body.
metalloproteinA protein that includes one or more metal atoms in its structure.
aberrantunusual; out of the ordinary course.
synista or synistatathose Neuropterous insects in which the mouth structures are undeveloped, forming an imperfect tubular structure: see elinguata.
data cleaningComputational processing to remove noise and artifacts from digital data prior to storage.
calorimeterdevice with which the quantity of heat energy released in a combustion reaction can be determined experimentally
michaelis constantThe half-saturation constant of an enzyme-catalyzed reaction that exhibits hyperbolic kinetics—that is, the concentration of substrate at which the reaction velocity is half of the maximal velocity
zwitterionA dipolar ion containing ionic groups of opposite charge.
knowledge miningThe extraction of useful knowledge from data patterns that have been rendered meaningful by the integration of information derived from external sources.
surface-to-volume ratioThe ratio of the total area of the outer surface of a three-dimensional object over the volume of that object.
pro-nucleusEither of the two haploid gamete nuclei just prior to their fusion in the fertilized ovum.
spiculeCrystalline or mineral deposits found in sponges, sea cucumbers, or urochordates
flyspecka tiny dark speck made by the excrement of a fly
diffractionThe bending of light caused by the presence of an object.
conductionThe direct transfer of thermal motion (heat) between molecules of objects in direct contact with each other.
toxicityThe degree to which a substance is able to damage an organism exposed to that substance
baseA compound, usually containing nitrogen, that can accept a proton (H+)
enthalpy changeFor a reaction, is approximately equal to the difference between the energy used to break bonds and the energy gained by the formation of new ones.
fossilAny evidence of past life, including remains, traces, imprints as well as life history artifacts
fat-solubleCapable of being dissolved in fat.
hydrophobicNot interacting effectively with water; in general, poorly soluble or insoluble in water
day-neutral plantA plant whose flowering is not affected by photoperiod.
mediumA nutrient-rich liquid used in tissue cultures.
mineralIn nutrition, a chemical element other than hydrogen, oxygen, or nitrogen that an organism requires for proper body functioning.
ambera transparent, clear, pale yellowish brown; of the color of amber [a mixture of pale cadmium yellow and a little burnt umber].
prokaryotea unicellular organism, either a bacterium or an archaeon, where the cell has a simple internal structure
intraepithelialWithin an epithelial cell layer.
steady stateIn enzyme-kinetic analysis, the time interval when the rate of reaction is approximately constant with time
organic chemistryThe study of carbon compounds (organic compounds).
perfoliatedivided into leaf-like plates: applied to antennae with disc-like expansions connected by a stalk passing nearly through their centres: also to any part possessing a well-developed leaf-like or plate-like expansion.
temperatureA measure of the speed or intensity of the ceaseless random motions that all the atoms and molecules of any substance undergo on an atomic-molecular scale
daltonUnit of molecular mass approximately equal to the mass of a hydrogen atom (1.66 × 10−24 g).
photosynthesisA chemical process by which green plants synthesize organic compounds from carbon dioxide and water in the presence of sunlight.
proteinA three-dimensional biological polymer constructed from a set of 20 different monomers called amino acids.
primary successionThe loss of the entire soil complex due to large, extreme disturbances such as volcanic eruptions or glaciers that  result in very slow succession due to complete mortality of all living individuals in the system.
conducting airwaysIn the lungs of an animal, the airways that do not participate in the exchange of respiratory gases between air and blood, but rather simply conduct air from one place to another.
heat of combustionquantity of heat energy given off when a specified amount of a substance burns in oxygen
nanomedicinethe union of nanoscale technology and medical treatment
microsatelliteA type of simple sequence length polymorphism comprising tandem copies of, usually, di-, tri- or tetranucleotide repeat units
chimeraAn organism with a mixture of genetically different cells.
lysisDisruption of cells with release of the contents.
replicative transpositionThe insertion of a transposable element at a new location without loss from the original location.
oxidationThe process by which electrons are removed from a chemical
uv reactivationA phenomenon in which survival of an ultraviolet-irradiated phage is greater upon infecting a host that has also been irradiated with UV than upon infecting a host that has not been irradiated with UV
supermoleculeany very large complex molecule; found only in plants and animals
loamThe most fertile of all soils, made up of roughly equal amounts of sand, silt, and clay.
diatomiteDiatomite, or diatomaceous earth, is a siliceous sedimaentary rock formed from the accumulations of diatoms or other nanoplankton.
collenchymaOne of the three major cell types in plants; are elongated and have thicker walls than
demographyThe study of statistics relating to births and deaths in populations.
catalystA substance that increases the rate of a chemical reaction without undergoing a permanent change in its structure
massThe amount of matter in an object; often used interchangeably with weight
electrophoresisA method of separating DNA fragments of different lengths by placing them in agarose gel and running electric current through the gel.
filtrationThe extraction of water and small solutes, including metabolic wastes, from the body fluid into the excretory system
stratosphereThe second layer of Earth's atmosphere, above the troposphere and below the mesosphere.
path integrationThe ability to remember the distances and directions traveled, to sum them, and then to calculate their return path.
hypoxiaReferring to the tissues of an animal, the state of having an unusually low level of O2.
pleiomorphicHaving the ability to change shape.
rete mirabileA Latin expression, meaning literally “wonderful net.” A morphological term referring to any intricately complex vascular system composed of closely juxtaposed, small-diameter arterial and venous blood vessels
colligative propertiesProperties of solutions that depend on the number of solute particles per unit volume; for example, freezing-point depression.
water vaporWater in the gaseous state.
lichensComposite organisms consisting of a symbiotic association of a fungus with a photosynthetic partner.
phA measure of hydrogen ion concentration equal to -log [H+] and ranging in value from 0 to 14.
moleculeA particle made up of two or more atoms joined by covalent bonds or ionic attractions.
molar massmass of one Avogadro's number, or "mole," of whatever particles are specified
genetic bankingThe deposit of an individual's genetic information to a database that enables the individual to control access.
p-type semiconductorsemiconductor that contains freely moving positive charges, or "holes"
enantiomorphsIsomers that are mirror images of one another.
faceta small face or surface: one of the parts, areas or lens-like divisions of the compound eye.
megabase pair1000 kb; 1  000 000 bp.
transportAn entirely general term referring to any and all movements of solutes, water, gases, or other materials from place to place, regardless of the mechanisms of movement.
grand malAnother term for generalized tonic-clonic seizures.
nonpolarReferring to a molecule or structure that lacks any net electric charge or asymmetric distribution of positive and negative charges
cell extractA preparation consisting of a large number of broken cells and their released contents.
isotopeOne of two or more atoms that have the same atomic number but different atomic weights.
calmodulinA Ca2+ protein that is found in all eukaryotes, calmodulin has a high degree of structural conservation and can bind to target enzymes and modulate their activity as a function of the cytosolic Ca2+ concentration.
allosteryThe word allosteric is derived from the Greek {\em allos} and {\em stereos{, means other-solid
recombineeringA term coined by Don Court to describe a method for vector construction based on homologous recombination in E
presynapticLiterally "before the synapse;" a structure or event that occurs before small gaps between nerve cells
crystal structureA structure obtained by x-ray diffraction analysis of a crystal consisting of an ordered array of biomacromolecules.
insertionthe point or place where a part is inserted: a part that is inserted: the act of inserting.
sphincterIn a vertebrate, a circular muscle, located between two chambers, that can contract tightly and steadily (tonically) for long periods of time, thus preventing exchange between the chambers.
mineralAn element essential to the functioning of a living organism.
respirationprocess by which humans and animals exchange the oxygen necessary for metabolism with the carbon dioxide produced by it
cation exchangeA process in which positively charged minerals are made available to a plant when hydrogen ions in the soil displace mineral ions from the clay particles
lateral geniculate bodyThe "visual middleman," the lateral geniculate body receives information from the eyes via the optic tract, does a preliminary analysis of the information, and then sends it onto the visual cortex.
calorieThe amount of heat energy required to raise the temperature of 1 g of water by 1°C; also the amount of heat energy that I g of water releases when it cools by 1°C
pyrogenBacterial substance that causes fever in mammals.
central pattern generatorA neural circuit (or a single neuron) that generates a behaviorally significant pattern of motor output in space and time without requiring temporally patterned sensory input.
metalloidselements between metals and nonmetals on the periodic table that do not fall cleanly into either group
epigenotypeA phenotype derived by mapping epigenetic parameters, such as DNA methylation.
synclineA fold of rock layers that is convex downwards
odds ratioA measure of relative risk that is usually estimated from case-control studies. 
ambient airthe outside air, that is, the air surrounding or encircling us
gram molecular weightThe weight in grams of a compound that is numerically equal to its molecular weight; the weight of 1 mole.
ecological releaseThe expansion of a population's niche (e.g., range of habitats or resources used) where competition with other species is alleviated.
acidA substance that increases the hydrogen ion concentration of a solution.
unilamellarConsisting of one layer, often used in reference to lipid monolayer structures.
primary consumerAn herbivore; an organism in the trophic level of an ecosystem that eats plants or algae.
laplace’s lawThe tension developed within the walls of a hollow structure exposed to a particular difference in pressure between inside and outside is directly related to the radius of the structure.
alpha particlepositively charged (2+) particle consisting of two protons and two neutrons (the nucleus of a helium atom)
photosyntheticAble to use sunlight energy to convert atmospheric carbon dioxide into organic compounds
uric acidAn insoluble precipitate of nitrogenous waste excreted by land snails, insects, and many reptiles, including birds.
compoundA substance formed by two or more
principle of superpositionThe idea that in deposits of sedimentary rock the oldest deposits are on the bottom and the youngest deposits are on the top
conduction(1) In the study of heat, the transfer of heat by intermolecular collisions through a material that is macroscopically motionless
peptideTwo or more amino acids joined by a peptide bond.
scaleFrom an animal perspective the level of spatial resolution of an environment perceived by an organism, from a plant perspective the area occupied by individuals in competing for light, water, and nutrients
tropical rainforestA terrestrial biome characterized by high levels of precipitation and warm temperatures year-round.
chromosomeA threadlike, gene-carrying structure found in the nucleus
psychiatricrelated to a set of mental, emotional, or behavioral disorders
heat capacityThe heat required to raise the temperature of a substance one degree Celsius.
split geneAn interrupted gene.
solid supportAn insoluble material to which reagents may be attached so that they may be readily separated from reaction by-products and solvents by filtration.
enzymecomplex protein which helps to speed biochemical reactions
dyad symmetryProperty of a structure that can be rotated by 180° to produce the same structure.
nernst equationAn equation that relates the redox potential to the standard redox potential and the concentrations of the oxidized and reduced form of the couple.
splicing enhancer sequencessequences that increase the probability that a nearby potential splice site will actually be used.
allochthonousRefers to something formed elswhere than its present location
oilA dietary lipid that is liquid at room temperature (e.g., olive oil, canola oil).
accumulatorsPlants containing intermediate concentrations of certain chemical elements (frequently metals or metallic compounds).
glucoseA six carbon simple sugar(C6H12O6) commonly used as a source of energy by the organism
navigationThe act of moving on a particular course or toward a specific destination using sensory cues to determine direction and position.
cheliceraThe first pair of appendages of a chelicerate arthropod
critical temperature(1) In the study of poikilotherms, a body temperature (high or low) at which animals have little or no ability to increase their rate of O2 consumption above their resting rate—making them incapable of much physical activity
unsaturatedIn lipid chemistry, characterized by one or more double bonds between carbon atoms in a carbon chain.
regressionIn geology, withdrawal of sea from land, accompanying lowering of sea level; in statistics, a function that best predicts a dependent from an independent variable.
peta-A prefix indicating 1015; a quadrillion.
vitamin aA lipid-soluble vitamin with antioxidant properties that may also play an important role in learning and memory.
scrapieA common transmissible spongiform encephalopathy (TSE) in sheep and goats.
capSee CRP.
paternalPertaining to the father.
limnetic zoneIn a lake, the well-lit, open surface waters farther from shore.
free radicalsAtoms or molecules that are highly reactive with other cellular structures because they contain unpaired electrons; free radicals can be very harmful to cells.
resource ratio hypothesisA proposal by David Tilman (1985) which models successional shifts in plant communities based on the assumption that succession is driven by a tradeoff in competition for nutrients in early succession, and for light in late succession.
exergonicA reaction that releases energy.
incidenceThe number of new events (such as being born with HD) in a population during a specified period.
abnormaloutside the usual range or course; not normal.
biosynthesisSynthesis by a living system.
collagenlong proteins whose structure is wound into a triple helix
meanStatistic that describes the center of a distribution of measurements; calculated by dividing the sum of all measurements by the number of measurements; also called the average.
abioticPertaining to nonliving properties, including light, air, water, nutrients and other physical and chemical properties of an environment.
fluorescenceLight of a specific range of wavelengths that is emitted from a molecule previously excited by energy of a different range of wavelengths
steady statecondition in which a dynamic system is in balance so that no net change occurs in the concentration of the major species involved
hsp 40The mouse analog of HDJ1.
parallelIn reference to the arrangement of parts in an electrical circuit, vascular system, or other analogous system in which substances flow from place to place, the parts of the system are in parallel if one path of flow branches to give rise to two or more paths in which the parts reside, so that only a fraction of the total flow passes through any one of the parts
anhydrideThe product of the condensation of two carboxyl or phosphate groups in which the elements of water are eliminated to form a compound with the general structure , where X is either carbon or phosphorus.
mass numbersum of the number of protons and neutrons in the nucleus of an atom
ribosome recycling factorA protein responsible for disassembly of the ribosome at the end of protein synthesis in bacteria.
annotationAnalysis and commentary added to sequence data in databases
fire regimeThe characteristic pattern of fire in a particular place.
a prioriDeduced from first principles; without prior knowledge.
icosahedronA regular geometric polyhedron with 20 equilateral trangular faces and 12 corners
enriched uraniumuranium that has a higher percent of U-235 than its natural abundance of about 0.7%
compactionsFossils that have undergone some degree of flattening of their three-dimensional structure.
aerosolsparticles, both liquid and solid, that remain suspended in the air rather than settling out
zgeA Chinese Ginkgo biloba extract.
tautomerOne of a set of possible alternative structures.
matrixthe formative substance from which cells and other structures are derived.
delayed fluorescence immunoassay(DELFIA) A fluorescence technique based on the use of a molecule with a long fluorescence half-life.
vital capacityThe maximum volume of air that a respiratory system can inhale and exhale.
diffusionThe net movement of molecules in the direction of lower concentration.
cccAn abbreviation for "circular, covalently closed" DNA molecules.
peptide mappingThe characteristic two-dimensional pattern (on paper or gel) formed by the separation of a mixture of peptides resulting from partial hydrolysis of a protein; also known as peptide fingerprinting.
aphidiluteina yellowish fluid found in plant lice, changed to a rich violet by alkaline reagents.
auxotrophicThe state of an organism when it is unable to synthesize a particular organic compound required for growth.
fissionThe separation of a parent into two or more individuals of approximately equal size
gmoAn abbreviation for "genetically modified organism"
virtual libraryAn combinatorial chemical library that is built in silico with the goal of evaluating possible structures.
ballismusuncontrolled, violent movements
physiotherapyAnother term for physical therapy.
bioelectronicsThe study of intermolecular electron transfer in biological processes
temperatureTemperature is really a way of measuring the average kinetic energy of all the molecules or atoms of the substance being studied
nucleusorganelle in the center of the cell which contains the chromosomes.
whorlAn arrangement of appendages, such as branches or leaves, such that all are equally spaced around the stem at the same point, much like the spokes of a wheel or the ribs of an umbrella
semi-cylindricallike a groove or half a cylinder.
niacinA precursor of nicotinamide
hibernateto pass the winter in a dormant condition.
hydrocarbonAn organic compound consisting solely of carbon and hydrogen.
ribosomeA structure consisting of small and large ribonucleoprotein units that is the site of intracellular protein biosynthesis.
desaturasesEnzymes that catalyze the introduction of double bonds into the hydrocarbon portion of fatty acids.
paxillaa small stake or peg: a bundle of spicular processes.
nucleus(1) An atom's central core, containing protons and neutrons
trans-displacementTransfer of a nucleosome from one DNA molecule to another.
epiphyteA plant that nourishes itself but grows on teh surface of another plant for support, usually on branches or trunks of tropical trees
pinnatifiddivided into feathers, as when wings are cleft nearly to the base.
monovalentPossessing a single charge or valency.
micromineralsquantities of Fe, Cu, and Zn that the body requires in lesser amounts
clottingThe process of forming lumps in a liquid.
matterAnything that takes up space and has mass
viscosityInternal friction in a moving fluid; a lack of intrinsic slipperiness between fluid layers that are moving at different linear velocities
evaporationThe removal of heat energy from the surface of a liquid that is losing some of its molecules
transpirationWater loss by evaporation from a plant, especially through the stomates on the leaves.
partial pressureA measure of the concentration of one gas in a mixture of gasesThe pressure exerted by a particular gas in a mixture of gases
facultative cellsCells that can live in the presence or absence of oxygen.
raceA poorly defined term for a set of populations occupying a particular region that differ in one or more characteristics from populations elsewhere; equivalent to subspecies
dimerTwo reversibly associated macromolecular structures; two covalently associated molecules.
nodea knot or knob: in the plural refers to the small segment or segment between thorax and main portion of abdomen in ants.
institutional review boardA specially constituted review body established or designated by an entity to protect the welfare of human subjects recruited to participate in biomedical or behavioral research.
amphotericCapable of donating and accepting protons, thus able to serve as an acid or a base.
metastasisThe spread of cancer cells to locations distant from their original site.
covalent bondStable chemical force that holds the atoms in molecules together by sharing of one or more pairs of electrons
mantleThat portion of the interior of the Earth that lies between the crust and the core.
hypertonicIn comparing two solutions, referring to the one with a greater solute concentration.
catalytic siteThe site of an enzyme involved in the catalytic process.
target dnai
carbon fixationThe incorporation of carbon from CO2 into an organic compound by an autotrophic organism (a plant, another photosynthetic organism, or a chemoautotrophic prokaryote).
controlDescribes the measures taken in a scientific experiment to account for unsuspected effects of anything other than the thing being tested
conditional lethal mutantA mutant that can grow under one set (permissive) of environmental conditions but dies under different (restrictive or nonpermissive) conditions.
acid rainrain that is more acidic than "normal" rain and that has a lower pH
heteropterouswith wings of different texture in different parts.
dry labRefers to experiments not performed at the lab bench.
redox reactionAnother term for an oxidation-reduction reaction
stochasticA random process; a process determined by a random distribution of probabilities.
laminateformed of thin, flat layers or leaves.
sedimentation coefficientThe value used to express the velocity at which a molecule or structure sediments when centrifuged in a dense solution.
cataractA clouding of the eye, making it difficult to see.
sexual reproductionProduction of offspring whose genetic constitution is a mixture of those of two potentially genetically different gametes.
selection pressureThe intensity of natural genetic selection processes
endothermicReferring to a chemical reaction that absorbs heat (i.e., has a positive change in enthalpy).
sievertinternational unit equal to 100 rem
brackish waterWater that is intermediate in salinity between seawater and freshwater
inhibitoryResulting in a decrease in activity or probability of activity
hippocampal regionRelating to the hippocampus, a complex structure involved with certain types of memory functions.
fasciculatebundled; clustered as in a bundle; tufted: a surface when covered with bundles of long hair.
coenzymeA molecule that binds to an enzyme and is essential for its activity, but is not permanently altered by the reaction
suicide ideationThoughts about fatally harming one's self
chromogenic substrateA substrate that changes color when modified by a specific enzyme.
biological magnificationA trophic process in which retained substances become more concentrated with each link in the food
sequestration enabling reagentA reagent that sequesters starting materials or reaction by-products, in order to simplify removal from a reaction mixture.
implicit memoryMotor memories or memories that deal with procedures (i.e
vascular resistanceThe resistance to blood flow through a blood vessel or system of blood vessels, calculated as the pressure drop divided by the flow rate.
kilocalorieA thousand calories; the amount of heat energy required to raise the temperature of 1 kg of water by 1°C.
galvanized ironiron coated with zinc
genomeThe complete set of genes in a cell
nonredundant databaseA database in which redundant entries have been noted and merged.
ß-lactam antibioticsAntibiotics taht contain a ß-lactam ring and act by inhibiting peptidoglycan synthesis
electrotaxisThe movement of organisms in response to an electric field.
tentaclea flexible sensory or tactile process; in some cases retractile: usually prefixed by a descriptive term indicating the structure to which it is attached.
lpsLipopolysaccharide
fischer projection formulasSee projection formulas.
embryoPlant or animal at an early stage of development.
exposureamount of a substance encountered, generally in reference to human contact with a toxic substance or a disease-causing organism
thermodynamic equilibriumA chemical reaction is in thermodynamic equilibrium when the forward and reverse rates of the reaction are equal, that is the net reaction rate is zero.
myceliumIn fungi, the mass of food absorbing cellular fibers(Hyphae) that make up the main part of the fungus
stabilityOften used to mean constancy; the propensity to return to a condition (a stable equilibrium) after displacement from that condition.
chromatographyA procedure for separating chemically similar molecules
microsequenatorA device for sequencing small amounts of sample.
multiplexThis word is mainly used as 'multiplexing', thus referring to a method by which many parameters are simultaneously tested and processed.
pulse-chaseAn experiment in which a short labeling period is followed by the addition of an excess of the same, unlabeled compound to dilute out the labeled material
aplasticIncomplete growth or development of a structure.
biogenesisthe production of life from antecedent life.
nucleusminuscule but highly dense region at the center of an atom that is composed of protons and neutrons
klenow fragmentThe large fragment of E
carrying capacityThe maximum population of a species that a particular ecosystem can sustain.
f-pilusA filamentous appendage encoded by the F-plasmid
parts per million1 part out of a million parts, unit of concentration
foveaAn eye's center of focus and the place on the retina where photoreceptors are highly concentrated
diurnalsuch insects as are active or habitually fly by day only.
salinityA measure of the salt concentration of water
gapdhGlyceraldehydephosphate dehydrogenase
thermodynamics(1) The study of energy transformations that occur in a collection of matter
biophysicsThe application of the techniques of physics to biological processes.
dentate gyrusA part of the hippocampal formation.
twintronA composite structure made up of two or more Group II and/or Group III introns embedded in each other.
fatty acidAn organic acid molecule consisting of a chain of carbon molecules and a carboxylic acid (COOH) group
conservationThe retention of sequence and 3-D structure by biomolecules under varying environmental and genetic conditions.
geologic recordThe division of Earths history into time periods, grouped into three eras: Archaean, Proterozoic, and Phanerozoic, and further subdivided into eras and epochs.
carcinogenA substance that causes cancer.
compact boneThe outer dense layer that forms the shaft of the long bones; made up of concentric layers of mineral deposits surrounding a central opening.
fmriStands for "functional magnetic resonance imaging." This technique uses magnetic fields to measure oxygen use by nerve cells in the brain
non-homologous end-joiningAnother name for the double-strand break repair process.
li 1379A Ginkgo biloba extract.
partial pressure(1) The pressure exerted by a particular gas within a mixture of gases
countercurrent exchangeExchange of heat, O2, or other substances by passive-transport processes (e.g., diffusion) between two closely juxtaposed fluid streams flowing in opposite directions (e.g., blood flowing in opposite directions in two blood vessels).
angstromA unit of measurement that was widely used until recently to describe molecular dimensions, but the unit nanometer (nm) is now more commonly used
paraffin [wax]A translucent, white, solid hydrocarbon with a low melting point
alcohol fermentationThe conversion of pyruvate to carbon dioxide and ethyl alcohol.
ca2+See "calcium ions".
climographA plot of the temperature and precipitation in a particular region
reactive oxygen speciesA highly reactive free radical that can result from excessive levels of iron in the body.
oxygen conformityA response in which an animal exposed to a decreasing O2 concentration in its environment allows its rate of O2 consumption to decrease in parallel.
currentrate of electron flow
second law of thermodynamicsThe law stating that in any chemical or physical process, the entropy of the universe tends to increase.
gel electrophoresisThe separation of nucleic acids or proteins, on the basis of their size and electrical charge, by measuring their rate of movement through an electrical field in a gel.
hypoxiaOxygen starvation at the cellular level.
new indication studiesNew phase II and III trials required when a drug seems promising as a new treatment for a different condition than it was originally approved for.
passage timeInterval between successive sub-cultures.
perpendicularupright: at right angles to horizontal.
ionAn atom or group of atoms that carries a positive or negative electric charge as a result of having lost or gained one or more electrons (negatively-charged particles)
teraflopA measure of supercomputer speed equivalent to 10 to the power of 12 floating point operations per second.
replicative transpositionType of transposition in which a copy of the transposable element moves to a new site while the original copy remains at the old site; increases the number of copies of the transposable element.
stromal cellsBone marrow cells that can be the source of other kinds of tissues.
acid precipitationRain, snow, or fog that is more acidic than pH 5.6.
laserA device that emits an intense coherent monochromatic light beam.
rolling circle replicationA mechanism for the replication of circular DNA
photodynamic therapyA treatment based on the uptake by target cells of photoactivatable molecules that destroy the cells upon exposure to a specific light source.
exothermicReferring to a chemical reaction that releases heat (i.e., has a negative change in enthalpy).
kearns-sayre syndromeA rare mitochondrial disorder that usually has an onset before the age of 20
chlorophyllA green pigment located within the chloroplasts of plants
dystoniaProlonged muscle contractions.
electronsubatomic particle with a much smaller mass than a proton or neutron and a negative electrical charge equal in magnitude to that of a proton, but opposite in sign
arid transition areacomprises the western part of the Dakotas, northern Montana east of the Rockies, southern Assiniboia, small areas in southern Manitoba and Alberta, the higher parts of the Great Basin and the plateau region generally, the eastern base of Cascade Sierras and local areas in Oregon and California.
lab-on-a-chipA microfabricated fluidics system designed to perform high-resolution biochemical analyses.
imineA molecule containing a nitrogen atom attached to a carbon atom by a double bond
outer earOne of three main regions of the ear in reptiles, birds, and mammals; made up of the auditory canal and, in many birds and mammals, the pinna.
saturated and unsaturatedThese terms refer to the number of available bonds for more hydrogens in a hydrocarbon or other organic compound
phototrophAn organism that can use the energy of light to synthesize its own fuels from simple molecules such as carbon dioxide, oxygen, and water; as distinct from a chemotroph.
critical periodThe time during prenatal development when a structure is sensitive to damanage from a mutation or an environmental intervention.
plasticizercompound added in small amounts to polymers to make them softer and more pliable
submitochondrial particleAn inside-out particle formed by the sonication of mitochondria
estivationSummer torpor; a physiological state that is characterized by slow metabolism and inactivity and that permits survival during long periods of elevated temperature and diminished water supplies
juvenile formAnother term for juvenile HD.
exa-A prefix indicating 1018; a quintillion.
respiratory mediumThe source of oxygen
syndromeA pattern of recognizable symptoms or signs characteristic of a disease.
nitrogen saturationprocess by which an area is overloaded with "nitrogen"; that is, when the reactive forms of nitrogen entering an ecosystem exceed the system's capacity to absorb the nitrogen
halophileA microorganism that grows optimally in a highly saline environment.
crmCross reacting material
protein linkage mapA protein-protein interaction network map.
replisomeA large multi-protein complex that performs DNA replication.
permineralizationFossilization process that occurs when minerals, carried by ground water, enter and harden in the pores of an organism's structures.
sub-as a prefix, means that the main term is not entirely applicable, but must be understood as modified in some way; e.g
multifactorial diseasePolygenic disease, i.e
pervSee porcine endogenous retrovirus.
hydrogen peroxideA waste product of the cell that is a dangerous free radical.
hydrocarboncompound that contains only the elements hydrogen and carbon
klenow fragmentA proteolytic fragment of DNA polymerase I that contains the DNA polymerase activity and the 3' to 5' proofreading activity but lacks the 5' to 3' exonuclease activity
trans fatA highly damaging type of fat which is produced when unsaturated fat is subjected to the process of hydrogenation.
mapping functiona mathematical equation describing the relation between recombination fraction and genetic distance
anticonvulsantPreventing or relieving convulsions
primerA structure that serves as a growing point for polymerization
fertilizationFusion of a female and male gamete (both haploid) to form a diploid zygote, which develops into a new individual.
critical micelle concentrationThe lowest concentration of a detergent at which molecules aggregate to form micellar structures.
ontologyThe creation of a systematically ordered data structure that enhances exchange of information between computers and scientists
leukotrieneA powerful inflammatory mediator
ala -aea wing or wings.
autotrophAn organism that can synthesize its own complex molecules from very simple carbon and nitrogen sources, such as carbon dioxide and ammonia.
akathisiaA drug-induced side effect often caused by antipsychotic drugs
parkinson's diseaseA neurodegenerative disorder that primarily affects one's ability to perform smooth movements
tau pathologiesneurodegenerative diseases related to problems with the tau protein found in nerve cells
fuel cellgalvanic cell that produces electricity by converting the chemical energy of a fuel directly into electricity without burning the fuel
hydrophilicA property meaning "water loving," describing molecules that are attracted to water.
heat shock proteinProteins that are synthesized in organisms in response to various environmental stressors (such as extremes in temperature)
ureaThe water soluble nitrogenous waste product of mammals and some other vertebrates that is formed by a combination of carbon dioxide and ammonia
pelagicPelagic organisms swim through the ocean, and may rise to the surface, or sink to the bottom
gradientIn a thermal cycler, a controlled, incremental temperature differential across a reaction block.
extentThe extended range of study, or the area included within the landscape boundary, such as a national park or state.
microenvironmentA place within a larger environment in which the physical and chemical conditions differ significantly from the average conditions characterizing the larger environment.
active restorationAccelerating the process or attempting to change the trajectory of succession
luteous -eusclay yellow [pale clay yellow].
eugenicsThe control of individual reproductive choices to achieve a social goal.
megapascalA unit of pressure equivalent to 10 atmospheres of pressure.
pointwise p valuein linkage analysis, the probability on the null hypothesis of exceeding the observed value of the statistic at one given position in the genome
hydrolysisA chemical process that lyses, or splits, molecules by the addition of water.
igneous rockAny rock solidified from molten or partly molten material.
neuroprotectionA process that involves protecting the nerve cells from deterioration due to neurodegenerative disease.
cellularPertaining to cells
carbohydratescompounds containing carbon, hydrogen, and oxygen, the last two elements in the same 2:1 atomic ratio as found in water
fidelityThe degree to which output reflects input
inflammationThe reaction that occurs in the affected cells and adjacent tissues in response to an injury or abnormal stimulation caused by a physical, chemical, or biological substance.
voltageA force caused by a difference in electric charge between two areas.
anaerobicOccurring in the absence of air or oxygen.
reverse osmosispurification process that uses pressure to force the movement of a solvent through a semipermeable membrane from a region of high solute concentration to a region of lower solute concentration
zygoteThe product of gamete fusion
nanomoleOne billionth mole; 10-9 mole.
sporadicOccurring in a random or isolated manner.
anaerobeAn organism that lives without oxygen
nicotinic acidAlso known as niacin.
cytoskeletonSystem of protein filaments in the cytoplasm of a eucaryotic cell that gives the cell a polarized shape and the capacity for directed movement
estuaryA body of water along a seacoast that is partially enclosed by land and that receives inputs of both freshwater and seawater; it is intermediate in salinity between freshwater and seawater.
endothermicterm applied to any chemical or physical change that absorbs energy
molalA unit of measure of chemical concentration; specifically, the molal concentration is the number of moles mixed with a kilogram of water to make a solution.
dual breatherAn animal that simultaneously possesses the ability to breathe from air and from water
giberrellinA plant hormone that regulates growth.
asperitiessurface roughenings or dot-like elevations.
parsingThe use of algorithms to analyze data into components.
herbivoreLiterally, an organism that eats plants or other autotrophic organisms
dynamic mutationan unstable expanded repeat that changes size between parent and child
carbohydratesOrganic molecules composed of carbon, hydrogen, and oxygen that serve as energy sources and structural materials for cells of all organisms
scientific methodThe principles and empirical processes governing investigation into the truth or falsity of a scientific question.
shagreeneda surface roughened with minute tooth-like projections.
c. elegansKnown as Caenorhabditis elegans
oxidationLoss of electrons from an atom or molecule as occurs when hydrogen is removed from a molecule or oxygen is added
nitric acidA chemical that increases blood flow; also used to make organic compounds in the body.
fatty acidA long-chain hydrocarbon containing a carboxyl group at one end
yotta-A prefix indicating 1024; a septillion.
foetid glandsglandular structures from which a foul smelling liquid may be ejected.
voltagedifference in electrochemical potential between the two electrodes
transposonA transposable genetic element that moves as a unit and inserts at new locations.
bioinformaticsUsing computing power, software, and mathematical models to process and integrate biological information from large data sets.
mutagenAny environmental agent that significantly increases the rate of mutation above the spontaneous rate.
chlorophyllThe pigment in green plants that absorbs solar energy.
biocombinatorial chemistryAn iterative process consisting of synthesis of combinatorial chemical libraries followed by screening in biological systems to evaluate function.
composite transposonA transposible element flanked by two copies of an IS element.
asphaltA dark bituminous substance found in natural beds
congenic strainsstrains of a laboratory animal that are identical except at one specific locus (Box 15.4).
e siteA position within a bacterial ribosome to which a tRNA moves immediately after deacylation.
x-ray diffractionMethod for analyzing the three-dimensional shape and structure of chemical substances
acclimatizationA chronic response of an individual to a changed environment in cases in which the new and old environments are natural environments that can differ in numerous ways, such as winter and summer environments, or low and high altitudes
stratosphereregion of the atmosphere above the troposphere; includes the ozone layer
acid depositiondeposition of either wet forms or dry forms such as rain, snow, fog, and cloud-like suspensions of microscopic water droplets often more acidic and damaging than acid rain
screenTo determine the presence or absence of a phenotype by testing for growth under different conditions (e.g., plus and minus an auxotrophic supplement or permissive and nonpermissive conditions)
gene cloningInserting DNA fragments into bacteria in such a way that the fragments will be stable and copied by the bacteria.
phytoalexinAn antibiotic, produced by plants, that destroys microorganisms or inhibits their growth.
accession numberThe unique identifier assigned to new sequence information submitted to a major database.
smith-watermanA sensitive algorithm for identifying sequence similarities.
htsHigh throughput screening
replicationThe synthesis of new deoxypolynucleotide strands.
burst sizeThe average number of phage released from a single infected bacterium during lytic growth
depleted uraniumcontains almost entirely U-238 (99.8%) and has been depleted of most of the U-235 that it once naturally contained
syncytiumA mass of cytoplasm containing several separate nuclei enclosed in a continuous membrane resulting from the fusion of individual cells.
proton donorThe donor of a proton in an acid-base reaction; that is, an acid.
conglobategathered together in a ball or sphere.
causal variance componentsIn a sibling analysis, the portions of phenotypic variance that are due to the underlying genetic and environmental sources of variance (e.g., additive genetic variance, dominance variance, environmental variance).
plant cell immobilizationEntrapment of plant cells in gel matrices; the cells are suspended in small drops of the material, which then is set or allowed to harden to make little carriers
risk assessmentorganized evaluation of scientific data to predict the probability of an occurrence
low-level radioactive wastewaste that is contaminated with smaller quantities of radioactive materials than HLW and specifically excludes spent nuclear fuel
hydrolysisThe cleavage of a molecule by the addition of water
global climate changeA change in the statistical distribution of weather over periods of time that can range from decades to millions of years.
pipetteA slender graduated tube into which small amounts of liquids are taken up by suction, for measuring and transferring.
guttatewith light spots or drops on a dark ground.
hydrophilicLiterally means water loving and refers to the fact that hydrophilic molecules are attracted to water
limiting nutrientAn element that must be added for production to increase in a particular area.
causalityA cause and effect relationship
nonelectrolytenonconducting solute in solutions
limpidclear and transparent: applied to wings and ornamentation.
hybrid cellA cell formed by fusion of two cells
cross reacting materialSee CRM.
dhaAbbreviation for docosahexaenoic acid.
borealfrom or belonging to the north: is that faunal region that extends from the polar sea southward to near the northern boundary of the United States and farther south occupies a narrow strip along the Pacific Coast and the higher parts of the Sierra-Cascade, Rocky and Alleghany Mountain ranges; divided into Arctic, Hudsonian and Canadian: see austral and tropical.
physical therapyTreatment of injury or disease by physical therapeutic means instead of by medical, surgical, or radiologic measures
transpirationThe evaporative loss of water from a plant.
atomThe smallest unit of matter that retains the properties of an element.
zero population growthA period of stability in population size, when the per capita birth rate and death rate are equal.
striatal neuronsNerve cells that make up the striatum
fmnAbbreviation for Flavin-mononucleotide.
allotropestwo or more forms of the same element that differ in their chemical structure and therefore in their properties
cost of resistanceThe fitness effects of an allele that confers resistance (often denoted by R) to a pesticide or antibiotic in the absence of the pesticide or antibiotic.
self-replicationSee self-renewal.
first law of thermodynamicsThe law stating that in all processes, the total energy of the universe remains constant.
isabelline -uspale yellow with some red and brown [chronic lemon with a little carmine and roman sepia].
virulenceUsually, the damage inflicted on a host by a pathogen or parasite; sometimes, the capacity of a pathogen or parasite to infect and develop in a host.
extremophileAn organism that grows optimally in extreme conditions, including extreme temperature, pressure, pH, ionic concentration, and pressure.
cardiac cycleOne heartbeat; consists of atrial contraction and relaxation, ventricular contraction and relaxation, and a short pause
angiostatinA plasminogen fragment with anti-angiogenic properties.
building blockA reagent used in combinatorial library synthesis.
double blindA study in which neither the investigator nor the participant are aware of which treatment a participant is receiving (ie experimental or control)
bioprospectingSearching for new plant and microbial strains that may serve as sources for natural products, such as phytopharmaceuticals.
prochiral moleculeA nonchiral molecule that lacks handedness and is optically inactive, but would become chiral by a change in one of the substituents at the chiral center
peroxidesChemicals capable of causing oxidative damage to cell membranes and other molecules.
controlA standard of comparison by which experimental results are evaluated
matterAnything that takes up space and has mass.
nuclear fissionthe splitting of a large nucleus into smaller ones with the release of energy and neutrons
rofecoxibA COX-2 inhibitor.
cyclea round or circle, e.g
nonshivering thermogenesisIn mammals and some birds, elevation of heat production for thermoregulation by means other than shivering
primary productionThe production of organic matter from inorganic chemical precursors
peristalsisOne of the gut’s principal modes of muscular activity, in which constriction of the gut at one point along its length initiates constriction at a neighboring point farther along the gut, producing a “wave” of constriction that moves progressively along the gut, propelling food material before it.
vacuoleA cytosolic membrane-bounded structure containing liquids.
trans-sulfuration pathwayA two-reaction pathway which degrades homocysteine.
ultra-high-throughput systemA high-throughput system capable of processing 100,000 samples a day.
summation(1) In excitable cells, the addition of graded subthreshold potentials (electrical events)
chromosomal rearrangementAnother term for a chromosomal mutation.
bystander effectSecondary effects on adjacent cells and tissues triggered by treatment of a primary target with a therapeutic agent.
vegetative growthGrowth of a plant by division of cells, without sexual reproduction.
excitatoryResulting in an increase in activity or probability of activity
catenaneAn interlocked pair of circular structures, such as covalently closed DNA molecules.
denitrificationA process facilitated by bacteria, in which nitrates (NO3) break down to molecular nitrogen (N2).
nitrogen-fixing bacteriabacteria that remove nitrogen from the air and convert it to ammonia
gravitropismA response of a plant or animal to gravity
polynucleotideA polymer consisting of many nucleotide monomers; serves as a blueprint for proteins and, through the actions of proteins, for all cellular activities
concentrationratio of amount of solute to amount of solution
migrationThe movement of a cell over a surface.
bicuspidateending in two points or cusps.
superansexceeding in size and length.
allometric coeffient(a) in the linear equation, log y = a log x + log b, the slope of the line.
animal physiologyThe study of the functional properties of animals; the study of “how animals work.”
postmortemPertaining to the period after death
polar transportThe directed movement within plants of compounds (usually endogenous plant growth regulators) mostly in one direction; polar transport overcomes the tendency for diffusion in all directions.
hydrostatic pressureThe sort of pressure that is developed in a fluid (gas or liquid) when forces are applied that tend to increase the amount of matter per unit of volume
exponentialReferring to a type of relationship between two variables in which the dependent variable goes up in multiplicative steps as the independent variable goes up in additive steps
allelopathyBiochemical production by a plant which alters growth and survival of other plants or itself.
dnaThe molecule that encodes genetic information
positive feedbackA process by which deviations of a property from a specific set-point level are reinforced, thereby tending to cause escalating changes in the property.
half-lifeThe number of years it takes for 50% of a sample of an isotope to decay.
topoisomeraseEnzyme that adds or removes rotations in a DNA helix by temporarily breaking nucleotide strands; controls the degree of DNA supercoiling.
prior probabilityin Bayesian statistics, the initially estimated probability of an outcome before all relevant information has been taken into account
optic vesicleEmbrogical Eye
cot curveA curve that indicates the rate of DNA-DNA annealing as a function of DNA concentration and time.
volume regulationThe maintenance of a constant or nearly constant volume (amount) of body fluid
stromatoliteRocklike structure composed of layers of prokaryotes and sediment.
x-overAn abbreviation for cross-over.
excretionthe act of getting rid of waste products: any material or substance produced by any secretory glands or structures and which is voided or otherwise sent out from them.
otic vesicleEmbrogical Ear
acid-neutralizing capacitycapacity of a lake or other body of water to resist a decrease in pH
volatilerefers to a substance that readily passes into the vapor phase
carcinogenAny chemical or physical agent that can cause cancer when cells or organisms are exposed to it.
metamorphic rockAny rock derived from other rocks by chemical, mineralogical and structural changes resulting from pressure, temperature or shearing stress.
respiratory gasesOxygen (O2) and carbon dioxide (CO2).
maximum tolerated doseThe highest daily dose of a drug that the average human body can tolerate before passing a threshold level of excessive toxicity
surface waterwater from lakes, rivers, and reservoirs
periphytonDense strands of algal growth that cover the water surface between the emergant aquatic plants
oblateflattened; applied to a spheroid of which the diameter is shortened at two opposite ends.
radiation sicknessillness characterized by early symptoms of anemia, nausea, malaise, and susceptibility to infection that results from a large exposure to radiation
neuroprotectiveThe property of preventing damage and degeneration to nerve cells.
heterologousConsisting of different elements.
racemic mixturemixture consisting of equal amounts of each optical isomer of a compound
sculpturethe markings or pattern of impression or elevation on an elytra or other body surface.
algorithmAn explicit computational procedure that uses a precise sequence of simple operations to perform a complex operation
sequence profileA sequence pattern representation emerging from comparison of multiple aligned sequences.
partial digestionTreatment of a DNA molecule with a restriction endonuclease under such conditions that only a fraction of all the recognition sites are cleaved
dikaryoticHaving two different and distinct nuclei per cell; found in the fungi
electrolyteconducting solute in solution
chemoautotrophAn organism that needs only carbon dioxide as a carbon source but that obtains energy by oxidizing inorganic substances.
primary down syndromeCaused by the presence of three copies of chromosome 21.
free radicalSee radical.
amenorrheaThe absence or abnormal stoppage of menstrual periods; a risk factor for osteoporosis.
standard free-energy changeThe free-energy change for a reaction occurring under a set of standard conditions : temperature, 298 K; pressure, 1 atm or 101.3 kPa; and all solutes at 1 ni concentration
ccd cameraA camera that uses CCD (charge coupled device) chips to convert photons to electrical or digital information.
clinical trialsA type of research study that is used to evaluate the effects of new drugs, medical devices, or other treatments on participants in scientifically controlled settings
faciesthe face: the general appearance or impression.
computational biologyComputational technologies for the collection, structuring, and mining of biological data that make possible prediction and knowledge discovery.
conformationThe spatial arrangement of substituent groups that are free to assume different positions in space, without breaking any bonds, because of the freedom of bond rotation.
computer-assisted molecular modelingComputational techniques for the exploration and visualization of molecular structures and properties.
glassA non-crystaline rock that results from very rapid cooling of magma.
unwinding proteinsProteins that help to unwind double-stranded DNA during DNA replication.
weatherThe state of the atmosphere including temperature, rain, cloud cover, wind and humidity.
normal distributionA bell-shaped frequency distribution of a variable; the expected distribution if many factors with independent, small effects determine the value of a variable; the basis for many statistical formulations.
il-1Abbreviation for interleukin-1.
correlatedderived from the same ancestral form: said of two or more features or qualities which bear a direct or an inverse relation to each other, but without implying a relation of cause and effect.
atomsmallest unit of an element that can exist as a stable, independent entity
solventsubstance capable of dissolving other substances
daily torporIn mammals and birds, a form of controlled hypothermia in which the body temperature is able to approximate ambient temperature for part (but only part) of each 24-hour day, generally on many consecutive days.
clusteringA bioinformatics technique for visualizing patterns in experimental data.
endangered speciesA species that is in danger of extinction throughout all or a significant portion of its range.
pedipalpsThe second pair of appendages of cheliceromorphs
traffickingThe movement of protein molecules between active and inactive locations in a cell, thereby controlling the functional activity of the protein molecules
selective permeabilityA property of biological membranes that allows some substances to cross more easily than others.
cryopreservationA process for storing biological material at very low temperatures for lengthy periods of time
mass numberThe mass number of an atom is the mass of the atom’s protons plus neutrons plus electrons.
pressureThe force a fluid (liquid or gas) exerts in a perpendicular direction on solid surfaces with which it is in contact
stoichiometryThe existence of fixed ratios in chemical reactions
polyphyleticderived or descended from several stems or sources.
asymmetric carbonA carbon that is covalently bonded to four different groups.
phThe negative of the common logarithm of the concentration of H+
adult formAnother term for adult-onset HD.
japanese knotweedA plant that contains resveratrol, an antioxidant compound in red wine.
x-ray diffractioncrystallography technique that generates a pattern of deflected X-rays passing through a crystal to reveal the nature of the crystal lattice
virtual cellA computational simulation of a living cell.
non-refinedrefers to breads and cereals in which the whole grain (including its bran and germ) are included in the food product
interspecific competitionCompetition for resources between plants, between animals, or between decomposers when resources are in short supply.
entomotomythat science which deals with internal structure of insects.
luminophoreA luminescent substance.
palearcticrelating to that part of the earth's surface including Europe, Africa north of Sahara, and Asia as far south as the southern edge of the Yang-tse-Kiang watershed and the Himalayas, and west to the Indus River.
neural networkA computational method for optimizing for a desired property based on previous learning cycles (training).
solventA substance, usually a liquid or gas into which another substance will dissolve
avogadro's numberThe number of molecules in a gram molecular weight of any compound (6.023 x 1023).
colicinBacterial proteins that are toxic to closely related strains of bacteria.
uniformitarianismAn important assumption in science that says that the physical laws that operate today have operated in the same manner in earlier times, back to close to the beginning of the universe
thioesterAn ester of a carboxylic acid with a thiol or mercaptan.
lamellateantennae with the club formed of closely opposed leaf-like surfaces, the concealed surfaces set with sensory pits.
hypertelybeyond the bounds of the useful: those forms whose resemblance to other objects is closer than needful, or without apparent object.
"enhanced greenhouse effect"process in which atmospheric gases trap and return more than 80% of the heat energy radiated by the Earth
divided attentionthe ability to split one's attention between more than one task
solar radiationThe visible and near-visible (ultraviolet and near-infrared) radiation emitted from the sun.
osmosisthe tendency of liquids to pass or diffuse through a membrane or septum.
half-lifetime required for half the nuclei in a sample of a radioisotope to undergo radioactive decay
yoctomoleOne septillionth mole; 10-24 mole.
half-lifeThe time required for the disappearance or decay of one-half of a given component in a system.
michaelis-menten kineticsA kinetic pattern in which the initial rate of an enzyme-catalyzed reaction exhibits a hyperbolic dependence on substrate concentration.
acetylationAn enzymatic reaction that results in the addition of an acetyl group to a biochemical.
scalingThe study of the relations between physiological (or morphological) features and body size within sets of phylogenetically related species, e.g., the study of metabolism-weight relations.
chromosomeThe self-replicating genetic structures of cells that contain DNA (the molecule that encodes genetic information)
continental crustThe Earth's crust that includes both the continents and the continental shelves.
scarifieda surface with irregular depressions, as if clawed or scratched.
semiconductormaterial that does not normally conduct electricity or heat well, but that can do so under certain conditions, such as exposure to sunlight
b1A cross in which an F1 or F1' individual is mated to one of its parents (P1) or to another individual that is genetically identical to one of its parents.
flagellaLong, flexible, helical protein structures that extend from the surface of the cell
herbivoreA heterotrophic animal that eats plants.
nitrogen fixationThe assimilation of atmospheric nitrogen by certain prokaryotes into nitrogenous compounds that can be directly used by plants.
haploidHaving a single set of chromosomes in the nucleus of each cell
data warehouseA collection of databases combined with a flexible data extraction system.
anastomoseTo form an interconnected network of tubules, vessels, or similar structures by patterns of branching, reconnection, and rebranching.
disturbanceAny process that removes biomass from the community; an abiotic event, natural or human-caused such as fires and storms, that kills or damages some organisms and thereby creates opportunities for other organisms to grow and reproduce.
fingerprintAny technique that enables the identification of substances by the comparison of patterns
helicasesProteins that unwind the DNA double helix.
metaboliteA chemical intermediate in the enzyme-catalyzed reactions of metabolism.
ventral hornAnother term for anterior horn.
wavelengthdistance between successive peaks of waves in the electromagnetic spectrum
acidicAdjective used to describe a substance or solution that has an abundance of positive hydrogen ions.
plasmid curingThe treatment of cells with a substance that interferes with plasmid replication.
alkanea hydrocarbon with only single bonds between the carbon atoms
genome-wide p valuein testing for linkage or association, the probability on the null hypothesis of observing the statistic in question anywhere in a screen of the whole genome – see also pointwise p value
effective stratospheric chlorinechlorine- and bromine-containing gases in the stratosphere
thermoclineA narrow stratum of rapid temperature change in the ocean and in many temperate-zone lakes.
pitchA function of a sound wave's frequency, or number of vibrations per second, expressed in hertz.
side effectsProblems that occur when treatment causes undesired effects, too much of the desired effect, or other problems occuring in addition to the desired therapeutic effect.
cecropinA basic polypeptide with antibacterial activity.
phytoremediationAn emerging nondestructive technology that seeks to cheaply reclaim contaminated areas by taking advantage of the remarkabJe ability of some plant species to extract heavy metals and other pollutants from the soil and to concentrate them in easily harvested portions of the plant.
annotationIn the study of genomics, the process of adding interpretive information to gene identities
triple responseA plant growth maneuver in response to mechanical stress, involving slowing of stem elongation, a thickening of the stem, and a curvature that causes the stem to start growing horizontally
catalytic converterdevice installed in the exhaust stream of an engine to reduce emissions
focusThe initial point within the Earth that ruptures in an earthquake, directly below the epicenter.
patch-clampA technique that uses a microelectrode to record current flow across a membrane.
tetrahedronfour-cornered figure with four equal triangular sides
optical mappingA technique for the direct visual examination of restricted DNA molecules.
short-day plantA plant that flowers (usually in late summer, fall, or winter) only when the light period is shorter than a critical length.
blunt endsFlush DNA ends generated by restriction enzymes that cut both DNA strands at the same point.
topologyThe study of the deformability of intact structures.
micronthe unit of microscopic measurement = 001 mm.: represented by the symbol µ: the symbol µµ represents .001 of a micron
sedimentation coefficientA physical constant specifying the rate of sedimentation of a particle in a centrifugal field under specified conditions.
armatureapplied to the spinous or chitinous processes on the legs, body or wings; or the corneous parts of genitalic structures.
stipulesPaired appendages found at the base of the leaves of many flowering plants.
isopreneThe hydrocarbon 2-methyl-1,3-butadiene, a recurring structural unit of the terpenoid biomolecules.
minisatelliteA type of simple sequence length polymorphism comprising tandem copies of repeats that are a few tens of nucleotides in length
chiral isomerscompounds with the same chemical formula but different three-dimensional molecular structures and different interaction with plane polarized light
hydrophobicNot dissolving readily in water (“water hating”); typically lipid-soluble.
herbaceousReferring to nonwoody plants.
gut microbiomePopulations of microbes, consisting of many species of bacteria and other heterotrophic microbes, living in the gut lumen of an animal.
photonA quantum, or discrete amount, of light energy.
epimersTwo stereoisomers with more than one chiral center that differ in configuration at one of their chiral centers.
vitamin b11Another name for folic acid.
mass spectrometryA method for identifying molecules based on the detection of the mass-to-charge ratio of ions generated from the molecule by vaporization and electron bombardment
vertebral columnSurrounds & protects nerve cord.Provides structural support:Large body size, fast movement.
enantiomersStereoisomers that are nonsuperimposable mirror images of each other.
neutronA neutron is a negatively charged particle in the nucleus of an atom
repressible enzymeIn bacteria, an enzyme whose synthesis is inhibited when its reaction product is readily available to the cell.
epiphyteA plant which grows upon another plant
metabolismThe total of physical and chemical processes that occur in an organism to maintain life.
bond energyThe energy required to break a bond.
ash-graya mixture of black and white, with a faint orange tinge: like ashes of anthracite coal.
electron donorA substance that donates electrons in an oxidation-reduction reaction.
fractional  saturationThe fractional saturation refers to the degree of saturation of an oligmeric structure to ligand, that is:
hydrogenationprocess in which hydrogen gas, in the presence of a metal catalyst, is added to a double bond and converts it to a single bond
autochthonousRefers to something formed in its present location
packagingThe encapsulation of DNA by viral coat proteins.
demographyThe study of statistics relating to birth and deaths in populations.
chlorofluorocarbonscompounds composed only of the elements chlorine, fluorine, and carbon
trisomy 13Presence of three copies of chromosome 13; in humans, results in Patau syndrome.
infraredheat radiation; the region of the electromagnetic spectrum with wavelengths longer than those of red visible light
interoperabilityAbility of different types of databases, applications, operating systems, and platforms to function in an integrated manner.
haptenA small molecule that is not immunogenic unless attached to a carrier protein.
cytochrome b-c1 complexAnother term for Complex III.
normalizationA database refinement process that organizes a database so that results obtained from queries to the database are always unambiguous.
germ-plasm theoryStates that cells in the reproductive organs carry a complete set of genetic information.
immigrationThe movement of individuals into a population or population area.
generalized tonic-clonicTonic-clonic seizures that are generalized, meaning they are caused by discharges from both sides of the brain
flangea projecting rim or edge.
daltonA unit of mass equivalent to the mass of a hydrogen atom (1.66 x 10-24 g)
antheridiumIn plants, the male garnet' a moist chamber in which gametes
supercoiled dnaDouble-stranded circular DNA in which either overwinding or underwinding of the duplex makes the circle twist
backcrossA mating between an F1 or F1' individual to one of its parents (P1 or P2) or to another individual that is genetically identical to one of its parents
combichemInformal term for combinatorial chemistry.
biosphereThe entire portion of Earth inhabited by life; the sum of all the planet's ecosystems.
two-hybrid systemsee Yeast two-hybrid system.
benthicOrganisms that live on the bottom of the ocean are called benthic organisms
obtusenot pointed: an angle greater than a right angle: opposed to acute
appendiculatebearing appendages; said of antennae where the joints have articulated appendages; of tarsal claws that have membranous processes at base.
caudatewith tail-like extensions or processes.
diatomic moleculemolecule that contains two atoms
cell cycle checkpointA period before entry into S or M phase of the cell cycle, a key point at which regulation is exerted.
niAbbreviation for neuronal inclusions.
isomerizationRearrangement of atomic groups within the same molecule without any loss or gain of atoms.
upanishadsSacred texts of Hinduism that deal with broad philosophical and theological questions.
combined dna index systemIn the United States, CODIS is a distributed database that is organized into three hierarchical levels: local, state, and national
biprefix, means two.
inflammatory bowel diseaseA chronic inflammatory disease that can affect any part of the gastrointestinal tract but most commonly affects a part of the small intestine.
gaSee geldanamycin.
non-permissive conditionsGrowth conditions not allowing a conditionally lethal mutant to survive.
corpus striatumAnother term for striatum.
fluorescenceThe emission of electromagnetic radiation following absorption of shorter wave length light.
renaturationThe process of returning a denatured structure to its original native structure, as when two single strands of DNA are reunited to form a regular duplex, or an unfolded polypeptide chain is returned to its normal folded three-dimensional structure.
multiple alignmentAn alignment of multiple sequences that inserts gaps into the individual sequences in order to align conserved sequences in the same column.
ethanol fermentationSee alcohol fermentation.
moleculea group of atoms arranged to interact in a particular way; one molecule of any substance is the smallest physical unit of that particular substance.
zwitterionA dipolar ion, with spatially separated positive and negative charges.
partial pressureA measure of the concentration of one gas in a mixture of gases; the pressure exerted by a particular gas in a mixture of gases (for instance, the pressure exerted by oxygen in air).
mg2+See Magnesium ion.
anaerobicThe absence of oxygen
intertidal zoneThe shallow zone of the ocean where land meets water.
electromagnetic spectrumThe entire spectrum of radiation ranging in wavelength from less than a nanometer to more than a kilometer.
nitrogen fixationThe conversion of gaseous nitrogen into a form usable by plants
laevis -igatussmooth, shining and without elevations: said of a surface.
electrolysisprocess of passing a direct current of electricity of sufficient voltage through water to decompose it into H2 and O2
attomoleOne quintillionth mole; 10-18 mole.
hap-1huntingtin-associated protein-1
diploid cellA cell containing two sets of chromosomes (2n), one set inherited from each parent.
greenhouse effectprocess by which atmospheric gases trap and return a major portion of the heat (infrared radiation) radiated by the Earth
amino acid analogSee analog.
redox-bufferActs to protect against oxidative damage.
cambrianGeologic period that begins the Paleozoic Era
gap penaltyA penalty subtracted from a sequence alignment score due to the introduction of a gap or the elongation of a gap.
calorieformerly defined as the amount of heat necessary to raise the temperature of exactly 1 g of water by 1°C
vitaminAn organic compound that an animal must obtain from food, symbiotic microbes, or another source other than the animal’s biosynthesis because the animal cannot synthesize it, yet requires it in small amounts.
free-energy changeThe amount of free energy released (negative ΔG) or absorbed (positive ΔG) in a reaction at constant temperature and pressure.
alzheimer's diseaseAn age-related dementia (mental deterioration) characterized by confusion, memory loss, and other symptoms.
isoelectric phThe pH at which a solute has no net electric charge and thus does not move in an electric field.
saturation kineticsThe kinetics characteristic of a chemical reaction or other chemical process that is limited to a maximum velocity by a limited supply of some type of molecule with which other molecules must reversibly combine for the reaction or process to take place.
parahormoneA substance with hormone-like properties that is not a secretory product (e.g., ethylene; carbon dioxide).
pedigreeA table, chart or diagram recording the ancestry of an individual.
bulk flowthe movement of water due to a difference in pressure between two locations
catenationThe linking of molecules without any direct covalent bonding between them, as when two circular DNA molecules interlock like the links in a chain.
st14a cell lineCells that exhibit quite accurately many of the properties of striatal nerve cells and can be engineered to express either normal or mutant huntingtin.
atomariuswith minute dots or points.
oceanic trenchDeep steep-sided depression in the ocean floor caused by the subduction of oceanic crust beneath either other oceanic crust or continental crust.
trehaloseA disaccharide found in microorganisms that is used to stabilize protein structure.
photonThe ultimate unit (a quantum) of light energy.
ionic bondA bond between two atoms involving a complete transfer of electrons
nitrogen-fixing bacteriaMicroorganisms that restock nitrogenous minerals in the soil by converting nitrogen to ammonia.
neurodegenerativeCharacterized by neurodegeneration
organic chemistrythe branch of chemistry devoted to the study of carbon compounds
tandem repeatsMultiple adjacent copies of the same sequence.
hawk-dove gameThis particular model pits a Hawk strategy (i.e., always try to injure your opponent and only withdraw from the contest if an injury is received) against a Dove strategy (i.e., always use a non-injurious display if the rival is another Dove and always withdraw if the rival is a Hawk).
pneumatic reactorSee airlift fermenter.
polarThe uneven distribution of postive and negative charges in small molecules, resulting in an electric dipole moment.
gas exchangeThe uptake of molecular oxygen from the environment and the discharge of carbon dioxide to the environment.
ferrobacteriaBacteria that utilize iron as an energy source.
surface tensionA measure of how difficult it is to stretch or break the surface of a liquid
molaritynumber of moles of solute present in 1 L of solution
sum of squaresThe sum of squared deviations from the mean for a set of observations; it is the numerator of the variance.
ammoniaA small, very toxic molecule made up of three hydrogen atoms and one nitrogen atom; produced by nitrogen fixation and as a metabolic waste product of protein and nucleic acid metabolism.
semiconservativeDNA replication is semiconservative because each daughter duplex contains one old and one newly synthesized strand (Figure 1.8).
protein affinity chromatographyA method for the direct characterization of protein-protein interactions.
f factorAn episomal genetic element that enables a bacterium to transfer extrachromosomal DNA to a second bacterium.
insulatorsee Boundary element.
calcium carbonateChemical that also occurs in limestone and marble
scientific notationsystem for writing numbers as the product of a number and 10 raised to the appropriate power
diauxieThe phenomenon whereby a bacterium, when provided with a mixture of sugars, uses up one sugar before beginning to metabolize the second sugar.
criteria pollutantsair pollutants for which EPA has set permissible levels based on their effects on human health and on the environment
secondary responseThe immune response that follows the second exposure to a substance.
active transportThe movement of a substance across a biological membrane against its concentration or electrochemical gradient with the help of energy input and specific transport proteins.
rain shadowAn arid region on the leeward side of a mountain range that experiences low levels of precipitation.
polymerase slippage modelA possible model for how expansions occur
distillationseparation process in which a solution is heated to its boiling point and the vapors of the various components are condensed and collected
acceptor controlThe regulation of the rate of respiration by the availability of ADP as phosphate group acceptor.
auxotrophicRequiring a nutritional supplement to grow.
equilibriumThe point at which the concentrations of two compounds are such that the interconversion of one compound into the other compound does not result in any change in free energy.
in situA Latin phrase meaning "in the original place"
elementAny substance that cannot be broken down to any other substance.
ethylenediaminetetraacetic acida complex molecule used medically to chelate metal ions in cases of lead or heavy metal poisoning
peptideTwo or more amino acids covalently joined by peptide bonds.
metallichaving the appearance of metal: applied to a surface or color.
hepatocarcinomaA cancer of the liver that is derived from hepatocytes.
radiant energythe entire collection of different wavelengths, each with its own energy
cytosolThe fluid portion of the cell, excluding organelles and other solids
micelleThe structure formed by amphipathic molecules in solution that places the polar group toward the solution and the hydrophobic group toward the interior.
helixA spiral structure with a repeating pattern.
grindingmaterial resulting from the process of grinding
isothermalOccurring at constant temperature.
homoeonomousof the same substance or texture.
aminotransferaseIncreases in concentration of this enzyme sometimes result in the elevation of toxic ammonia levels
elementpure substance that cannot be broken down into simpler ones by any chemical means
tetracyclinean antibiotic drug that is used for medicine and for research
peptideTwo or more amino acids are joined by a so-called peptide-bond.
hairpin-mediated polymerase slippage modelA possible explanation for why expansions occur
genetic engineeringCommon term for recombinant DNA technology.
distributed generationplacing powergenerating modules of 30 megawatts or less near the end user
refinedrefers to breads and cereals in which the fibrous bran and germ are removed from the grain by machinery
proton acceptorA functional group capable of accepting a proton from a proton donor molecule.
saturated fatty acidA fatty acid containing a fully saturated alkyl chain.
immunogenicCapable of stimulating an immune response.
resistance exerciseExercise that consists of relatively short periods of high-intensity muscular actions against a large load, often repeated with intervening interruptions
mycorrhizaeMutualistic associations of plant roots and fungi
sequence skimmingA method for rapid sequence acquisition in which a few random sequences are obtained from a cloned fragment, the rationale being that if the fragment contains any genes then there is a good chance that at least some of them will be revealed by these random sequences.
free radicalA very reactive atom or molecule typically possessing a single unpaired electron.
single-lens eyeThe camera-like eye found in some jellies, polychaetes, spiders, and many molluscs.
glycationA non-enzymatic reaction that adds a carbohydrate group to a protein or peptide.
tonic-clonicSeizures that involve both tonic and clonic phases
chomosome paintingThe identification of chromosomes using combinatorially labeled fluorescent chromosomal probes in a wide array of colors
trihybrid crossA cross between two individuals that differ in three characteristics (AA BB CC X aa bb cc); also refers to a cross between two individuals that are both heterozygous at three loci (Aa Bb Cc X Aa Bb Cc).
solventThe dissolving agent of a solution
root systemAll of a plant's roots that anchor it in the soil, absorb and transport minerals and water, and store food.
similaritySequence identity between two nucleotide sequences
photochemical reaction centerThe part of a photosynthetic complex where the energy of an absorbed photon causes charge separation, initiating electron transfer.
fermentationEnzyme-catalyzed reactions that occur without O2, such as reactions that accomplish the anaerobic breakdown of compounds to liberate energy for metabolic use.
constitutiveProduced in a constant amount, not subject to regulation
http://huntington-study-group.org/]http://huntington-study-group.org/]
sequestrationprocess of keeping some things apart
turnoverThe mixing of waters as a result of changing water-temperature profiles in a lake.
arAbbreviation for androgen receptor.
electrochemical potentialThe energy required to maintain a separation of charge and of concentration across a membrane.
interferenceDegree to which one crossover interferes with additional crossovers.
hydrocarbonAn organic molecule consisting only of carbon and hydrogen.
strataLayers of sedimentary rock that were deposited at different times.
copulation chambera chamber or cell excavated by certain Scolytid beetles in their burrows, in which copulation takes place: = rammel-kammer.
condensed structural formulachemical formula in which bonds are not drawn out explicitly, but simply understood to contain an appropriate number of bonds
insulatorsee Boundary element
resonance hybridA molecular structure that is a hybrid of two structures that differ in the locations of some of the electrons
latent heat of vaporizationThe heat that must be provided to convert a material from a liquid to a gas at constant temperature (called latent because although heat is provided, the temperature of the material does not rise)
maldi-tof msThe abbreviation for Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry, a high-throughput protein sequencing method based on embedding samples in a matrix from which they are desorbed by laser light.
chitinouscomposed of chitine {Scanner's comment: sic} or like it in texture: as a color term is amber yellow.
v•o2maxAn animal’s maximal rate of O2 consumption
picomoleOne trillionth mole; 10-12 mole.
percentparts per hundred; sometimes abbreviated as pph
electroencephalograph testingA technique for recording electrical activity in the brain.
oxygenAn element with eight protons and eight electrons and with an atomic mass averaging a bit over 16
rigidinflexible: holding a direct course.
tentaclesAppendages which are flexible, because they have no rigid skeleton
capacitance coefficientIn the study of respiratory gas exchange, the change in total gas concentration per unit of change in gas partial pressure in air, water, or a body fluid like blood
kinetic energyEnergy of motion.
nitrogen cycleset of chemical pathways whereby nitrogen moves through the biosphere
metabolismThe set of processes by which cells and organisms acquire, rearrange, and void commodities (e.g., elements or energy) in ways that sustain life.
mudA defective derivative of phage Mu
saturated fatty acidA fatty acid in which all the bonds between carbon atoms in the carbon-chain backbone of the molecule are single bonds
thymus glandThe thymus gland lies at the root of the neck behind the breastbone
osmotic pressurePressure generated by the osmotic flow of water through a semipermeable membrane into an aqueous compartment containing solute at a higher concentration.
squamous cellsFlat cells that constitute the surface of the skin.
matrixA medium in which things are formed, developed, or embedded.
halonscompounds similar to CFCs, in which bromine or fluorine atoms replace some or all of the chlorine atoms
oxido-reductaseAn enzyme that catalyzes oxidation-reduction reactions.
computational chemistryComputer-based modeling and prediction of the structure of chemical compounds most likely to bind a protein drug target
hibernationA physiological state that allows survival during long periods of cold temperatures and reduced food supplies, in which metabolism decreases, the heart and respiratory system slow down, and body temperature is maintained at a lower level than normal.
planelevel, flat; applied to a surface.
proprietary databaseA copyrighted database accessible by subscription.
hspAbbreviation for heat shock protein.
x-rayAn energy beam of very short wavelengths (0.1 to 1000 Å) produced by the bombardment of various materials with high velocity electrons.
peptideA description of two linked amino acids.
phytohormoneA plant hormone.
creb-binding proteinA transcriptional co-activator of phosphorylated CREB (Cyclic AMP Response Element Binding Factor).
photolithographyA process that utilizes selective masking to generate light patterns that direct chemical transformations within a photosensitive surface.
saponinA glycosidic surfactant produced by plant cells.
hydrophobicPreferring not to be in contact with water, as is the case with the hydrocarbon portion of a fatty acid or phospholipid chain.
oxygen therapyAdministration of concentrated oxygen for therapeutic reasons
probabilityStatistics: The frequency of occurrence of an event.
microtransponderCube-shaped (~100µm), miniature radio-frequency transmitters out of silicon
homeostasisMaintenance of an equilibrium state by some self-regulating capacity of an individual.
petaflopA theoretical measure of computer speed that corresponds to a thousand trillion (1015) floating point operations per second.
non-polarA hydrophobic (water-hating) chemical group.
catalystchemical substance that participates in a chemical reaction and influences its rate or speed without undergoing permanent change
book lungsLungs within which sheets of gas-exchange tissue alternate with sheetlike air spaces, like pages of a book slightly separated by air
immune complex diseaseA disorder characterized by the presence of immune complexes in bodily fluids.
protuberanceany elevation above the surface.
gamma rayhigh-energy, shortwavelength photon emitted from the nucleus with no charge or mass
steric hindranceHindrance of an enzymatic reaction by structural features of the substrate or the enzyme.
neurotoxicA substance that damages or destroys nerve tissue.
homologous pair of chromosomesTwo chromosomes that are alike in structure and size and that carry genetic information for the same set of hereditary characteristics
apical meristemEmbryonic plant tissue in the tips of roots and in the buds of shoots that supplies cells for the plant to grow in length.
regulatorA characterization of an animal in regard to environmental variables
potable waterwater that is fit for human consumption
molecular replacementA method for solving biomacromolecular structure based on the use of a model derived from a related, previously solved structure.
intermediate disturbance hypothesisThe concept that moderate levels of disturbance can foster greater species diversity than low or high levels of disturbance.
eluateThe effluent from a chromatographic column.
reformulated gasolinesoxygenated gasolines that also contain a lower percentage of certain more volatile hydrocarbons such as benzene found in nonoxygenated conventional gasoline
tetrabenazineA dopamine depletor used to treat chorea.
rolling circleA method for the replication of circular double-stranded DNA.
cytochemistryThe use of compound-specific stains, combined with microscopy, to determine the biochemical content of cellular structures.
inclusion bodiesAnother term for neuronal inclusions.
reformingprocess using heat, pressure, and catalysts to rearrange the atoms within molecules
diprotic acidAn acid having two dissociable protons.
epicormicA shoot arising spontaneously from an adventitious or dormant bud on the stem or branch of a woody plant often following exposure to increased light levels or fire.
specific heatThe amount of energy (in joules or calories) needed to raise the temperature of 1 g of a pure substance by 1 °C.
monochromaticof one color throughout.
moleculeThe smallest particle of a substance that retains all the properties of the substance and is composed of one or more atoms.
bioleachingThe recovery of precious metals from ore by biological processes.
amyloid plaquesAnother term for beta-amyloid plaques.
bipolar disorderDepressive mental illness characterized by swings of mood from high to low; also called manic-depressive disorder.
phA measure of acidity and alkalinity
"doping"process of intentionally adding small amounts of other elements to pure silicon
iterationA single round of data processing
nicheThe particular range of conditions that species
metalselements that are shiny and conduct electricity and heat well
yeast extractA water soluble preparation extracted from common yeast
curationThe process of verifying and enhancing data submitted to bioinformatics databases
soluble supportA support for a reaction that is soluble under reaction conditions, but readily separable by some simple process
trinucleotide repeatAnother term for triplet repeat.
hypotonicIn comparing two solutions, referring to the one with a lower solute concentration.
carbocationA positively charged carbon atom; also called a carbonium ion.
paleosolSoil horizon from the geologic past.
paternallyFrom or related to the father of an individual
termination factorsProteins that are exclusively involved in the termination reactions of protein synthesis on the ribosome.
blastoporal grooveThe groove formed as result of the formation of bottle cells
amphitrophicCapable of photosynthetic or chemotrophic growth.
red nucleusA small part of the brain involved in the control of movement.
gamma-carbolinesA type of small molecule whose derivatives have recently been associated with antipsychotic, antibiotic and antitumor activity.
molarA unit of measure of chemical concentration; specifically, the molar concentration is the number of moles dissolved in a liter of solution.
substrateSubstance on which an enzyme acts in biochemical reactions; or, in hybridisation arrays, the particular material onto which the biomolecules are deposited
multiregional evolutionA hypothesis that holds that modern humans in the Old World are descended from Homo erectus populations that left Africa over 1 million years ago.
zoned reserveAn extensive region of land that includes one or more areas undisturbed by humans surrounded by lands that have been changed by human activity and are used for economic gain.
isotopeOne of several atomic forms of an element, each containing a different number of neutrons and thus differing in atomic mass.
secondary cell wallA strong and durable matrix often deposited in several laminated layers for plant cell protection and support.
decomposerAn organism that breaks down the tissue and/or structures of dead organisms.
protonA subatomic particle with a single positive electrical charge, found in the nucleus of an atom.
blasta family of programs that search sequence databases for matches to a query sequence
filamenta thread: a long slender process of equal diameter throughout: an elongated appendage.
stop codonA UAG, UAA
amphotericDescribes a molecule that reacts as an acid with bases, and as a base with acids.
degradeto break something down
microprocessorAn integrated electronic circuit designed to carry out a specific set of operations.
solidapplied to an organ usually jointed, when these joints form into one mass; e.g
dirty bomb" device that employs a conventional explosive to disperse a radioactive substance
oilstriglycerides that are liquid at room temperature
peptideA small polymer usually containing fewer than 30 amino acids connected by peptide bonds.
substrateMolecule that undergoes a change in a reaction catalyzed by an enzyme.
angstromA unit of length equal to 10-10 m.
confocal microscopyA light microscope technique that constructs an image from information derived from point-by-point scanning of a field.
drosophilaThe common fruit-fly, whose full name is Drosophila Melanogaster, is often used as an animal model in scientific experiments.
dormancyA period of suspended growth and metabolic activity
broth cultureMicroorganisms grown in a liquid medium.
optical tweezersA laser-based technique that utilizes minute forces exerted by light waves to measure and to manipulate biomolecules.
heterotrophAn organism that obtains the energy it needs to stay alive by breaking up organic compounds that it obtains from other organisms, thereby releasing the chemical-bond energy of those organic compounds
jouleA unit of energy: 1 J = 0.239 cal; 1 cal = 4.184 J
epstein-barr virusA herpes virus that causes mononucleosis.
visible lightThat portion of the electromagnetic spectrum detected as various colors by the human eye, ranging in wavelength from about 380 nm to about 750 nm.
planktonMostly microscopic organisms that drift passively or swim weakly near the surface of oceans, ponds, and lakes.
kinetic energyenergy of motion
uv absorbance spectroscopyA method for measuring the concentration of a compound by determining the amount of ultraviolet radiation absorbed by a sample.
topsoilA mixture of particles derived from rock, living organisms, and humus.
protoplasmAll the contents of a cell, including the nucleus
chromatographyA process used for separating mixtures by virtue of different affinities of substances for various media, such as paper, gas, or gelatin.
schizophreniaSevere mental disturbance characterized by psychotic episodes in which patients lose the ability to distinguish reality from hallucination.
branchpointAn intermediate in a biochemical pathway that can follow more than one route in following steps.
dispersalThe distribution of individuals within geographic population boundaries.
regression(n) A drop in sea level that causes an area of the land to be uncovered by seawater.
lethargyA state of tiredness or inactivity.
desideratum -atasome thing or things needed or desired.
puniceuscarmine red [carmine].
accommodationThe automatic adjustment of an eye to focus on near objects.
messenger cascadeA process in which an initial message is greatly amplified in a cascade of ensuing messages, resulting in cellular change.
copolymerpolymer built from two or more different monomers
oxygenated gasolinesblends of petroleum-derived hydrocarbons with added oxygen-containing compounds such as MTBE, ethanol, or methanol (CH3OH)
aerobic expansibilityAn animal’s peak rate of O2 consumption during locomotion expressed as a ratio of its resting rate of O2 consumption
dispersion forcesattractions between molecules that result from a distortion of the electron cloud that causes an uneven distribution of the negative charge
optimum phThe characteristic pH at which an enzyme has maximal catalytic activity.
psychostimulantsA group of drugs that lead to increased motor activity and decreased fatigue as well as an induced euphoric state.
peatExtensive deposits of undecayed organic material formed primarily from the wetland moss Sphagnum.
water vapor pressure(1) In reference to a gas phase, the prevailing partial pressure of gaseous water
electron acceptorA substance that receives electrons in an oxidation-reduction reaction.
tibetan buddhismA branch of Buddhism, which traveled to Tibet from India sometime after Buddhism had traveled to eastern China from India
sculptureda surface, when marked with elevations or depressions or both, arranged in some definite manner.
fdaFood and Drug Administration
satellitethis word has two different meanings in genetics
phytohormoneA substance that stimulates growth or other processes in plants
tetramerStructure resulting from the association of four subunits.
transition state analogA molecule that mimics the transition state of an enzymatic reaction.
semicircularlike the half of a circle.
dissociation constantAn equilibrium constant for the dissociation of a molecule into two parts (e.g., dissociation of acetic acid into acetate anion and a proton); Kd.
propaguleAny structure capable of giving rise to a new plant by asexual or sexual reproduction, including bulbils, leafbuds, etc.
polypeptideA linear molecule composed of two or more amino acids linked by covalent (peptide) bonds
endophyteA microorganism living within plant vascular tissue.
monoprotic acidAn acid having only one dissociable proton.
vitrificationprocess in which the spent fuel elements or other mixed waste from a nuclear reactor are encased in ceramic or glass
data miningThe automated or semi-automated search for relationships and global patterning within data
generation timeThe time it takes for a cell to double its mass under specified conditions.
oxygenation(1) Referring to water, the dissolution of O2 in that water
gene synthesisThe synthesis of an entire gene by hybridizing oligonucleotides, which are subsequently joined enzymatically.
maximal exerciseExercise that requires an individual’s maximal rate of O2 consumption.
intermittent breathingBreathing in which breaths or sets of breaths are regularly interrupted by extended periods of apnea.
s valueThe unit of measurement for a sedimentation coefficient.
mass spectrometerAn instrument that determines the exact mass of charged particles or ions by measuring the flight path through a set of magnetic and electric fields
secondary coolantwater in the steam generators of a nuclear reactor core that does not come in contact with the core
minocyclineAn antibiotic commonly used to treat arthritis and acne
coenzymeAn organic molecule that associates with enzymes and affects their activity.
mamlMicroarray Markup Language - adopted from "XML, Extensible Markup Language" - that provides a framework for describing experiments done on all kinds of DNA arrays
exsculptate -tusa surface with irregular, more or less longitudinal depressions, as if carved.
dipeptideA two-residue peptide.
rosette-shapedin the form of a double rose: clustered round a centre.
gene lineageIn the study of evolution, a set of genes that are related by descent from a common ancestral gene; also a representation of the family tree of such a set of genes.
electrophoresisThe movement of particles in an electrical field
identification particlea tiny particle of material that can be added to a product to indicate the source of manufacture
simple diffusionTransport of solutes, water, gases, or other materials that arises from the molecular agitation that exists in all systems above absolute zero and from the simple statistical tendency for such agitation to carry more molecules out of regions of relatively high concentration than into such regions.
microfluidicsHandling of volumes of liquids as small as 0.1 nanoliter.
catalytic crackingcatalysts used to promote molecular breakdown at lower temperatures than thermal cracking
regression coefficientStatistic that measures how much one variable changes, on average, with a unit change in another variable.
auriculatewith an ear-like appendage or, in antennae, with the basal joint distended into a concave, plate-like ear which envelops the rest of the structures.
hybrid vehiclevehicle that combines conventional gasoline engines with battery technology
citalopramA drug used to treat depression associated with mood disorders
frequencyThe proportion of a population falling into a particular category.
prader-willi syndromePrader-Willi syndrome (PWS) is a metabolic disorder caused by genetic defects; among its features are short stature, mental retardation, poor muscle tone, and hyperphagia, which leads to childhood obesity.
laminar flowFlow of a fluid without turbulence
capsule(1) A sticky layer that surrounds the cell walls of some prokaryotes, protecting the cell surface and sometimes helping to glue the cell to surfaces
workForce x DistanceEnergy transfer that occurs as a mass is moved through a distance against an opposing force
stagerefers to the period of development; e.g
passive restorationAllowing natural succession to occur in an ecosystem after removing a source of disturbance. The recovery of the deciduous forests in the eastern United States after the abandonment of agriculture is a classic.
flax oilA type of oil derived from flax plant that contains a great amount of omega-3 fatty acids.
denaturation of proteinsThe unfolding of a protein molecule, usually by high temperatures or ionic detergents such as sodium dodecyl sulfate (SDS).
primer extensiona method of identifying the transcription initiation site
ground stateThe lowest electronic energy state of an atom or a molecule.
colloidA mixture made up of a liquid and pa ticles that (because of their large size) remain suspended in that liquid.
testthe secretionary covering of Coccidae, and especially such as are waxy, horny or glassy.
correlation coefficientStatistic that measures the degree of association between two or more variables
asepticProcedures that prevent the contamination of cultures, media, animals, and persons by extraneous microorganisms.
lightElectromagnetic radiation, typically that which is visible to either our eyes or the eyes of other animals
polysomnographyThe technique of monitoring normal and abnormal physiologic activity during sleep.
epiglottisA cartilaginous flap that blocks the top of the windpipe, the glottis, during swallowing, which prevents the entry of food or fluid into the respiratory system.
protomeristemSee promeristem.
activation energyThe amount of energy (in joules) required to convert all the molecules in 1 mole of a reacting substance from the ground state to the transition state.
expansethe distance between the apices or other widest point of the wings when fully spread.
deconvoluteTo simplify or render less complex.
hippocampalOf or relating to the hippocampus.
specific heatquantity of heat energy that must be absorbed to increase the temperature of 1 g of a substance by 1°C
a formA duplex DNA structure with right-handed twisting in which the planes of the base pairs are tilted about 70° with respect to the helix axis.
hemicryptophytesPlants with their perennating buds at or near the soil surface (e.g
molecular seive chromatographySee Gel filtration chromatography.
unequal cross-overA recombination event that occurs between DNA molecules that are not fully aligned
depositionAny accumulation of material, by mechanical settling from water or air, chemical precipitation, evaporation from solution, etc.
carbon sourceA nutrient which provides the carbon required for cellular biosynthesis.
bifurcatedivided, not over half its length, into two dull points; forked.
cyclosporinAn immunosupressant used in transplant surgery to prevent rejection of transplants.
short tandem repeatA type of simple sequence length polymorphism comprising tandem copies of, usually, di-, tri- or tetranucleotide repeat units
gmoGenetically modified organism
detritusrubbed off; a surface partly denuded.
fungistaticThe ability to inhibit the growth of fungi
heterotrophicThe ability of an organism to use an organic molecule as carbon source.
retroposonA retroelement that does not have LTRs.
chain reactionterm that generally refers to any reaction in which one of the products becomes a reactant
magnetoreceptionA mechanism by which specialized animal cells are able to detect Earth’s magnetic field by direct or indirect means.
unsaturated hydrocarbonhydrocarbon molecule that contains one or more double bonds between the carbon atoms
data loggerA small microcomputer with a large amount of memory that can be placed in or on an animal to collect and store time-labeled information on physiological or behavioral variables
downregulationA downward shift in the catalytic activity of an enzyme, the rate of functioning of a biochemical pathway, or the rate of some other similar process brought about in a controlled manner by a regulatory system.
lamotrigineAn anticonvulsant drug normally used to control seizures or stabilize mood
hydrolysisHydrolysis is the process by which a molecule is split in two by the addition of a water molecule, which has the chemical formula H2O
emigrationThe movement of individuals out of a population.
biotechnologyThe use of the properties of living things to make products or services
cerebral spinal tapA medical procedure to insert a needle into the spinal cord and collect spinal fluid
genusan assemblage of species agreeing in some one character or series of characters; usually considered as arbitrary and opinionative, though some consider it a natural assemblage.
micrometera millionth (10-6) of a meter
r2See coefficient of determination.
thermoplastic polymerplastics that can be melted and reshaped over and over again
catalystA chemical agent that changes the rate of a reaction without being consumed by the reaction.
concatemermultiple copies of the same sequence joined tandemly end to end.
preconsumer contentwaste left over from the manufacturing process itself, such as scraps and clipping
goffereda surface with regular impressions, closely set, and separated by narrow ridges: reticulated.
microsatellitesmall run (usually less than 0.1 kb) of tandem repeats of a very simple DNA sequence, usually 1–4 bp, for example (CA) n
physical therapistA specialist trained in the treatment of diseases and injury through exercise and physical activities.
mycorrhizaeMutualistic associations of plant roots and fungi.
quantum mechanicsA theory that explains the behavior of elementary particles, atoms, and energy in terms of probabilities.
suberoylanilide hydroxamic acidAn HDAC inhibitor.
endurance exerciseExercise that consists of many repetitions of relatively low-intensity muscular actions over long periods of time
ironAn element that plays a role in the transport of oxygen by the blood.
compoundpure substance made up of two or more elements in a fixed, characteristic chemical combination
entropyA measure of the degree of disorder or randomness in a system; the higher the entropy, the greater the disorder.
dichotomous charactera character like polydactyly, which some people have and others do not have – as opposed to a continuous character like height, which everybody has, but to differing degree.
ketoseA simple monosaccharide in which the carbonyl group is a ketone.
nucleotideA nucleoside with one or more phosphate groups linked via an ester bond to the sugar moiety
visualizationThe graphic representation of data, patterns within data, or knowledge based on analysis of data patterns.
resveratrolA phytoalexin found mainly in red wine that exhibits both antioxidant and anti-inflammatory abilities.
heterothermyThe property of exhibiting different thermal relations from time to time or place to place
life tableA table of data summarizing mortality in a population.
autoimmune diseaseAn immunological disorder in which the immune system turns against self.
biomineralizationThe deposition of minerals by microorganisms and plant and animal cells.
optic nerveA collection of nerve cells that project visual information from the eyes to the lateral geniculate nucleus.
electronA negatively charged particle; one of the three basic kinds of particles that make up an atom
carcinogenA chemical that can cause cancer.
seldiSurface-Enhanced Laser Desorption/Ionisation invented by T
newborn screeningTesting newborn infants for certain genetic disorders; done most commonly for phenylketonuria and other metabolic diseases that can be prevented by early treatment or intervention.
expanded polyglutamine chainwhen a normal protein that has a certain number of glutamines in a chain is mutated, so that the number of glutamines in the chain increases, it is an expanded chain
photonA quantum of light; the energy of a photon is proportional to its frequency; E = hv, where E is energy; h is Planck's constant, 6.62 × 10-27 erg-second; and v is the frequency.
basicAdjective used to describe a substance or solution that contains a relatively low amount of positive hydrogen ions.
anergyA deficient immune response due to inactivated B- and T-lymphocytes.
peptide mappingSame as fingerprinting.
genetic distanceAny of several measures of the degree of genetic difference between populations, based on differences in allele frequencies.
light use efficiencyThe efficiency of using light to fix carbon (i.e., the proportion of light absorbed that is eventually converted to biomass).
salting inThe increase in solubility that is displayed by typical globular proteins upon the addition of small amounts of certain salts, such as ammonium sulfate.
activityThe true thermodynamic activity or potential of a substance, as distinct from its molar concentration.
animal modelsNon-human animals used in laboratories to study the biology of HD, usually having HD genes and related symptoms
constitutive enzymesEnzymes synthesized in fixed amounts, regardless of growth conditions.
guard cellA specialized dermal cell in plants that is used to regulate the size of the pores(stoma) on the surface of plants through which gas exchange and water loss take place
pharmaceutical agentSee therapeutic agent.
salinityThe sum total concentration of inorganic dissolved matter in water, usually expressed as grams of dissolved matter per kilogram of water.
indirect measurementA measurement procedure that quantifies a property by measuring something other than what the definition of the property specifies
high-content screeningSimultaneous multiparametric analysis of complex systems, such as living cells.
exciteTo raise a molecule from the ground state to the excited state.
activity coefficientThe factor by which the numerical value of the concentration of a solute must be multiplied to give its true thermodynamic activity.
tumescencea swelling or tumid enlargement: a puffed up area.
ketosisA condition in which the concentration of ketone bodies in the blood or urine is unusually high.
excentricnot in the centre; revolving or arranged about a point that is not central.
bipolar disorderalso known as manic-depression, this disorder is characterized by alternating periods of extreme moods
archimedes’ principleThe principle that states that a body immersed in a fluid is buoyed up by a force equal to the weight of the fluid displaced.
phosphorolysisThe cleavage of a bond by orthophosphate; analogous to hydrolysis referring to cleavage by water.
cleaveChop up.
daltonA unit of measure for atomic and molecular mass, equal to 1/12 the mass of an atom of the most abundant carbon isotope, 12C
oxidative damageThe harmful condition that occurs when there is an excess of free radicals, a decrease in antioxidant levels, or both.
bioinformaticsScience dealing with the classification, storage, retrieval and analysis of genomic and proteomic information; molecular modelling.
gymnospermA vascular plant that bears naked seeds-seeds not enclosed in specialized chambers.
time constantThe time required for an exponential process to reach 63% of completion
empiricalBased on data rather than merely reasoning.
boosterA secondary immunization used to increase a weak immune response to a primary immunization.
maficTerm used to describe the amount of dark-colored iron and magnesium minerals in an igneous rock
cover slipA small, thin piece of glass used to cover a specimen on a microscope slide.
mobilemovable: having the power of motion.
osmotic pressureThe pressure generated by the mass flow of water to that side of a membrane-bounded structure that contains the higher concentration of solute molecules
multidimensional nmrThree- and four-dimensional NMR methods for the detailed characterization of protein structure.
oxygen regulationA response in which an animal exposed to a decreasing O2 concentration in its environment maintains a stable rate of O2 consumption.
hibernation(1) In mammals and birds, usually refers to a form of controlled hypothermia in which the body temperature is able to approximate ambient temperature continuously for two or more consecutive days during winter
reciprocal crossesPairs of genetic crosses which in one case DNA from strain #1 is transferred into strain #2 and in the second case the strain #2 is used as a donor to transfer the same region into strain #1
microtubulenano-sized hollow cylinder with outer diameter between 20 nm and 30 nm
volumes percentMilliliters (at STP) of gas dissolved or chemically combined within a fluid per 100 milliliters of the fluid.
sedimentary rockRock formed from sand and mud that once settled in layers on the bottom of seas, lakes, and marshes
vertical cephalic bristlesin Diptera, are two pairs, inner and outer, inserted more or less behind the upper and inner corner of the eye; erect, or the inner pair convergent, the outer pair divergent.
fractusbroken: also applied to a geniculate antenna.
forcingsfactors that affect the annual global mean surface temperature
lower austral zoneoccupies southern part of United States from Chesapeake Bay to the great interior valley of California
synergyWhen effects of two factors (such as toxicity of two chemicals) combine so that their effect together is significantly greater than the sum of the effects of each factor by itself.
dextrorotatory isomerA stereoisomer that rotates the plane of plane-polarized light clockwise.
hip-1huntingtin-interacting protein-1
neutral solutiona solution that is neither acidic nor basic; that is, one that has equal concentrations of H+ and OH-
addition ruleStates that the probability of any of two or more mutually exclusive events occurring is calculated by adding the probabilities of the individual events.
seriesIn relation to the arrangement of parts in an electrical circuit, vascular system, or other analogous system in which substances flow from place to place, the parts of the system are in series if they occur sequentially along a single path of flow, so that all flow must occur sequentially through all parts
snowball earth hypothesisThe hypothesis that glaciers covered the planet's landmasses from pole to pole 750-570 million years ago, confining life to very limited areas.
mixturephysical combination of two or more substances present in variable amounts
estuaryThe area where a freshwater stream or river merges with the ocean
frequencynumber of waves passing a fixed point in one second
michaelis–menten equationAn equation that describes the relation between reaction velocity and substrate concentration in an enzyme-catalyzed reaction that exhibits hyperbolic kinetics
b cellA B-lymphocyte.
bias of ascertainmentdistortions in a set of data caused by the way cases are collected – for example, severely affected people are more likely to be ascertained than mildly affected people
bulk flowThe movement of water due to a difference in pressure between two locations.
early-onset hdAnother term for juvenile HD.
flagellumthat part of the antenna beyond the pedicel: a whip or whip-like process: the tail-like process of a spermatozoön.
anti-inflammatoryReducing inflammation
heatThe total amount of kinetic energy due to molecular motion in a body of matter
carcinogenA molecule that can transform normal cells into cancer cells.
osmotic pressureThe property of a solution that allows one to predict whether the solution will gain or lose water by osmosis when it undergoes exchange with another solution; osmosis is always from lower osmotic pressure to higher osmotic pressure
osmolaritySolute concentration expressed as molarity.
isotropicGrowth in all directions (opposite of polarized growth).
levorotatory isomerA stereoisomer that rotates the plane of plane-polarized light counterclockwise.
molecular biologyThe interpretation of biological events in terms of the physics and chemistry of molecules within cells.
high-performance liquid chromatographyA column chromatography method with many applications in biochemistry.
troposphereThe first layer of Earth's atmosphere; it contains approximately 75% of the atmosphere's mass and 99% of its water vapor.
organic compoundcompound that contains mainly carbon and hydrogen
arachidonic acidAn omega-6 fatty acid
x-ray diffraction patternThe pattern obtained after diffraction of X-rays through a crystal.
middle pleural areain Hymenoptera; the median of the three areas between lateral and pleural carinae: = 2d pleural area.
rflpSee Restriction fragment length polymorphism.
carbohydrateGeneral term for certain polyhydroxyaldehydes, polyhydroxyketones, or compounds derived from these usually having the formula (CH2O)n
solutionA homogenous mixture of two or more substances.
suspension feedingFeeding on objects suspended in water that are very small by comparison to the feeding animal
parallel analysisSimultaneous analysis of thousands of samples.
autotrophA microorganism that synthesizes all organic molecules from inorganic sources.
litervolume occupied by 1000 g of water at 4 °C
disaccharideA double sugar, consisting of two monosaccharides joined by dehydration synthesis.
heuristicA method based on empirical information that has no explicit rationalization.
degenerate codeA code in which a single element in one language is specified by more than one element in a second language.
calibration graphgraph made by carefully measuring the absorbencies of several solutions of known concentration for the species being analyzed
titration curveA plot of the pH versus the equivalents of base added during titration of an acid.
weigle reactivationThe increased survival of phage after UV irradiation if they infect cells that have previously been exposed to a lose dose of UV
aquifergreat pool of water trapped in sand and gravel 50–500 ft below the surface
auxotrophA microorganism strain that requires nutrients not required by the wild-type strain.
genetic research cycleThe process of learning about and developing treatments for genetic diseases
hydroxyl radicalA free radical.
optical fiberA glass or plastic fiber surrounded by a material with a lower index of refraction
interactionStrictly, the dependence of an outcome on a combination of causal factors, such that the outcome is not predictable from the average effects of the factors taken separately
alkylating agentAn organic compound able to transfer an alkyl group to nucleotides.
organic moleculeA molecule consisting of carbon, hydrogen and often oxygen and other elements
entropyA measure of disorder or uncertainty of a system
neuterthe term applied to workers or undeveloped females in some Hymenoptera: indicated by * or *, an imperfect form of Venus sign.{Scanner's comment: I have no characters to represent the symbols
pvpSee polyvinylpyrrolidone.
microsatellitesmall run (usually less than 0.1 kb) of tandem repeats of a very simple DNA sequence, usually 1–4 bp, for example (CA) n
productivityThe amount of carbon and energy fixed in photosynthesis by plants and other producers.
zeptomoleOne-sextillionth mole; 10-21 mole.
out of africaA hypothesis which holds that modern humans evolved in Africa, moving to the rest of the Old World between 100 000 and 50 000 years ago, displacing the descendants of Homo erectus that they encountered.
postconsumer contentused material that would otherwise have been discarded as waste
volatile organic compoundsvapors of incompletely burned gasoline molecules or fragments of these molecules
cognitiverelated to the mental processes of knowing, thinking, learning, and judging.
triglyceridean ester of three fatty acid molecules and one glycerol molecule
prototrophA microorganism that is able to grow on minimal medium containing only a carbon source and inorganic salts.
catalystA compound that facilitates a chemical reaction—in which covalent bonds are made or broken—without, in the end, being modified by the reaction
cyclocreatineAn analog of creatine
fragile siteConstriction or gap that appears at a particular location on a chromosome when cells are cultured under special conditions
saturated fatA type of fat found mainly in meats, butter, and dairy products which, due to its chemical structure, tends to pack very tightly and raise levels of unhealthy cholesterol.
nitrifying bacteriaMicroorganisms that restock nitrogenous minerals in the soil by converting nitrogen to ammonia
chloramphenicolAn antibiotic that inhibits protein synthesis by binding to the 50s ribosomal subunit and blocking the peptidyltransferase reaction
correlation coefficientA statistical measure of the degree of linear relationship between two variables that indicates the strength of that relationship
overexploitationHarvesting by humans of wild plants or animals at rates exceeding the ability of populations of those species to rebound.
epiphyteA plant that nourishes itself but grows on the surface of another plant for support, usually on the branches or trunks of tropical trees.
mycorrhizaeSymbiotic association between a fungus and the roots or rhizoids of a plant
choreaGreek word for "dance." Chorea refers to an uncontrollable dance-like motion of twisting and turning that affects many persons with HD.
one hybrid systemA method for detecting protein-DNA interactions.
bilamellarConsisting of two layers, often used in reference to lipid bilayer structures.
transgression(n) A rise in sea level relative to the land.
lead compoundA chemical compound that is considered the most likely to become an effective therapeutic treatment.
condensationA change in the physical state of a compound from a gas to a liquid.
voltageA measure of the potential energy present because of charge separation
diurnalAn animal who is active during the day and sleeps at night.
photorespirationOxygen consumption occurring in illuminated temperate-zone plants, largely due to oxidation of phosphoglycolate.
folateThe naturally occurring version of folic acid.
ssdnaSingle-stranded DNA.
protein engineeringGenerating proteins with modified structures that confer properties such as higher catalytic specificity or thermal stability.
cuticlethe outer skin or skin layer.
triple responseA plant growth maneuver in response to mechanical stress, involving slowing of stem elongation, a thickening of the stem, and a curvature that causes the stem to start growing horizontally.
conservative transpositionA transposition event where the transposable element is lost from its original location and inserted at a new location.
pangaeaThe supercontinent formed near the end of the Paleozoic era when plate movements brought all the landmasses of Earth together.
linking numberThe number of times one closed circular DNA strand is wound about another; the number of topological links holding the circles together.
impressed -usa surface with shallow depressed areas or markings.
auxotrophic requirementA nutritional supplement required for growth of an auxotrophic strain.
genomeThe term describes the total genetic information of a specific unit of inheritance such as e.g., the nucleus or the mitochondria.
colicinA polypeptide secreted by bacteria which inhibit or prevent the growth of related bacteria which lack the corresponding colicin immunity proteins
upwellingThe raising of benthic nutrients to the surface waters
colligative propertiesThe properties of an aqueous solution that depend simply on the number of dissolved entities per unit of volume, rather than on the chemical nature of the dissolved entities
replica platingA technique in which an impression of a culture is taken from a master plate and transferred to a fresh plate
hyphaIn fungi, a thread like structure consisting of cells one after the other
molecular mimicsChemical compounds that resemble biomolecules and recognize and bind their targets.
exotoxinA toxic protein that is secreted by a prokaryote and that produces specific symptoms even in the absence of the prokaryote
hygroscopicdescribes a substance that readily absorbs water from the atmosphere and retains it
viabilityCapacity for survival; often refers to the fraction of individuals surviving to a given age, and is contrasted with inviability due to deleterious genes.
electricityflow of electrons from one region to another that is driven by a difference in potential energy
amyloidProteins with beta sheet structure that form extracellular aggregates.
assayA chemical analysis of a substance to determine its components.
radioactivityspontaneous emission of radiation by certain elements
mid-domain effectPredicts a peak of diversity at the midpoint along any domain simply by the fact that the ranges of more species overlap in the middle of a domain (like a mountain or an island) than on the edges.
uv irradiationElectromagnetic radiation with a wavelength shorter than that of visible light (200-390 nm)
homolog1
stromaThe fluid of the chloroplast surrounding the thylakoid membrane; involved in the synthesis of organic molecules from carbon dioxide and water.
pediculosisa state of lousiness, or the abnormal condition caused by the multiplication of lice on the body: sec phthiriasis.
radiant heat transferTransfer of heat by electromagnetic radiation between two surfaces that are not in contact
progenySee offspring.
osmoleAn Avogadro’s number of osmotically effective dissolved entities; a set of 6.022 × 1023 osmotically effective dissolved entities.
bacteriostaticA condition which prevents the growth of bacteria without killing them.
oxygenAn element active in physiological processes and crucial to brain functioning.
bootstrap valueThe statistical value obtained by bootstrap analysis.
dna replicationSynthesis of a new copy of the genome.
sedimentary rockAny rock resulting from the consolidation of sediment.
analytical modelA model in which the relationships among variables are defined using equations.
bronzethe color of old brass.
de novo pathwayA biochemical pathway that starts from elementary substrates and ends in the synthesis of a biochemical.
cardiac cycleOne heartbeat; consists of atrial contraction and relaxation, ventricular contraction and relaxation, and a short pause.
microtaggant(trademark) a microscopic and traceable identification particle used to trace explosives or other hazardous materials or to prevent counterfeiting
lipid-solubleCapable of dissolving in substances made of compounds known as lipids
energythe capacity to do work or supply heat
photoperiodDay length; the number of hours of daylight in a 24-hour day.
three-hybrid systemA technique for the detection of complexes that involve three proteins; also used to refer to a technique for the detection of RNA-protein interactions.
ubiquinoneAnother term for coenzyme Q10.
pm2.5particulate matter with an average diameter less than 2.5 µm, also called fine particles
chemotaxisA cell's sensing of and movement toward, or away from, a specific chemical agent.
tautomeric shiftA reversible change in the position of a hydrogen atom in a molecule which results in the conversion of the molecule between different isomers
environmentThe place in which an organism lives, and the circumstances under which it lives
electrochemical equilibriumA term that is synonymous with equilibrium, but emphasizes that the equilibrium state for an ion or other charged solute depends on both electrical and chemical effects
carbohydratesOrganic molecules composed of carbon, hydrogen, and oxygen that serve as energy sources and structural materials for cells of all organisms.
oxygen debtThe extra oxygen (above the normal resting level) consumed in the recovery period after strenuous physical exertion.
half-lifeThe half-life of a substance is the amount of times it takes for half of the original molecule to be chemically degraded or eliminated in some other way (for example, in the urine)
sodium butyrateAn HDAC inhibitor.
transpositionThe movement of a genetic element from one site to another in a DNA molecule.
obcordateinversely heart-shaped, with the point applied to the base of another object or part.
isoelectric point or phThe pH at which a protein has no net charge.
standard curveA quantitative research tool used to determine the concentration or copy number of an unknown substance
extensible markup languageA set of specifications for formatting web documents that allows the creation of custom data tags that enable flexible transmission of data between applications and servers.
compact boneThe outer dense layer that forms the shaft of the long bones; made up of concentric layers of mineral deposits surrounding a central opening
alaAbbreviation for alpha-linolenic acid.
chemical symbolone- or two-letter abbreviation for an element
acetaldehydeA natural element found in alcohol that produces damaging free radicals.
coreThat portion of the interior of the Earth that lies beneath the mantle, and goes all of the way to the center
green fluorescent proteinA protein produced by jellyfish that glows when viewed under a specific wavelength of light
structural bioinformaticsThe process of predicting the 3-D structure of a protein from comparison of primary sequence alignment, secondary structure prediction, homology modeling, threading prediction, NMR data, and crystallographic data.
mineralnaturally occurring element or compound that usually has a definite chemical composition, a crystalline structure, and is formed as a result of geological processes
endangered speciesA species that is likely to become extinct in all or a major portion of its range.
crop rotationThe alternation of planting a nonlegume one year and a legume the next year to restore concentration of fixed nitrogen in the soil.
segregrateSee segregration below.
half-lifeThe time required to reduce something by one-half; applies, for example, to the concentrations of substances such as hormones, stored voltages, and radioactivity.
mitoribosomeA mitochondrial ribosome
parkinson's diseaseA motor disorder caused by a progressive brain disease and characterized by difficulty in initiating movements, slowness of movement, and rigidity.
stem photosynthesisPhotosynthesis that occurs in the stem (the main stalk of a plant that bears buds and shoots) of a plant.
heat of vaporizationThe quantity of heat a liquid must absorb for 1 g of it to be converted from the liquid to the gaseous state.
abyssal plainThe ocean floor offshore from the continental margin, usually very flat with a slight slope.
microfluidicsLab-on-a-chip technology based on the transport of nanoliter or picoliter volumes of fluids through microchannels within a glass or plastic chip
anaerobeAny microorganism that grows in the absence of molecular oxygen.
acidosisA state in which the pH of the body fluids is excessively acid.
electron density mapA 3-D representation of the electron density of a molecular structure based on x-ray diffraction data
critical massamount of fissionable fuel required to sustain an atomic chain reaction
detritusDead organic matter.
significant figurea number that correctly represents the accuracy with which an experimental quantity is known
oculi -usthe eyes: an eye: refers to the compound eyes.
bufferA substance that consists of acid and base forms in a solution and that minimizes changes in pH when extraneous acids or bases are added to the solution.
deaurateof the color of gold; golden.
hpa axisThe hypothalamic-pituitary-adrenal axis (HPA axis) is a major part of the neuroendocrine system that controls reactions to stress
suspensionA mixture of a liquid and small particles that stay in the liquid rather than settling out because of kinetic energy of the solvent’s molecules
mating typeThe equivalent of male and female for a eukaryotic microorganism.
noncompetitive inhibitorAn inhibitor of enzyme activity whose effect is not reversed by increasing the concentration of substrate molecule.
hemeA particular metalloporphyrin containing iron in the ferrous state: ferrous protoporphyrin IX
atomThe smallest existing particle of a pure element that can exist and still maintain the properties (or chemical characteristics) of that element
moleculeThe smallest unit of matter of a substance that retains all the physical and chemical properties of that substance, consisting of a single atom or a group of atoms bonded together
quantizednoncontinuous energy distribution that consists of many individual steps
reductionGain of electrons by an atom or molecule as occurs when hydrogen is added to a molecule or oxygen is removed
confoundAn extraneous variable that may influence the results of an experiment.
groundwaterwater pumped from wells that have been drilled into underground aquifers
baseA substance that reduces the hydrogen ion concentration of a solution.
biradiateconsisting of, or with two rays or spokes.
futile cycleSee pseudocycle.
confocal microscopeA high-powered microscope used for visualizing extremely small cellular components with beams of fluorescent light.
proparapterathe paraptera of the prothorax: the terms erroneously applied in this connection.
hyperbaric oxygen therapyA treatment where the patient is inside a chamber and breathes oxygen at higher-than-atmospheric pressure
schizophreniaa psychiatric disorder that usually involves problems with perceptions or expressions of reality, significant social or occupational problems, disorganized thinking, and delusions or hallucinations.
phytosanitaryPlant health, including quarantine.
densityThe number of individuals per unit area or volume.
epidemiologistSomeone who studies epidemiology.
fertilityThe number of live births per parent; the capacity to conceive and generate live offspring.
fixationThe chemical preservation of cells or tissues.
crenulatedHaving an uneven 'saw-tooth'-like edge
myoclonic seizureA seizure characterized by myoclonus (sudden, brief muscle contractions).
blowing agenteither a gas or a substance capable of producing a gas used to manufacture a foamed plastic
mad cow diseaseAnother term for bovine spongiform encephalopathy (BSE).
phytochromeA plant chromoprotein involved in the regulation of light-dependent growth processes.
transformation frequencyThe relative proportion of cells in a population that are transformed in a single experiment.
phosphagensCompounds that can donate high-energy phosphate bonds to ADP to make ATP; thus, compounds that act as stores of high-energy phosphate bonds
snornpAbbreviation for Small Nucleolar Ribonucleoprotein.
reservoira case or cavity for the storage of any fluid or secretion.
aspiration pneumoniaoccurs when a person inhales food into their respiratory tract
methanogenA microorganism that obtains energy by using carbon dioxide to oxidize hydrogen, producing methane as a waste product.
dolomiteA carbonate sedimentary rock composed of more than 50 percent of the mineral calcium-magnesium carbonate (CaMg(CO3)2).
faunathe assemblage of animals inhabiting a region or country.
spherulea minute sphere or globule.
dihommogamma-linoleic acidAn omega-6 fatty acid that can be converted into arachidonic acid (AA).
mass-to-charge ratioThe ratio of the mass of an ion being analyzed to its charge.
petalOne of the outer appendages of a flower, located between the outer sepals and the stamens
cretaceouschalky white: the third, uppermost and latest of the three great divisions of the mesozoic or secondary rocks.
mass spectrometryTechnique uesed to measure and analyse a substance in terms of the ratios of mass to charge of its components.
screeninglooking for evidence of a particular disease such as cancer in persons with no symptoms of disease.
f-factorAn E
endergonicAn energy-requiring reaction.
submolecularA chemical component that exists at a lower level of complexity than individual molecules (electrons, ions, free radicals).
pfuAbbreviation for plaque forming unit.
global warmingpopular term used to describe the increase in average global temperatures
carrying capacityThe population density that can be sustained by limiting resources.
lyaseAn enzyme that catalyzes the removal of a group to form a double bond, or the reverse reaction.
hydrophilicDissolving readily in water (“water loving”).
trans fatsfats that have been transformed by the addition of hydrogen to unsaturated vegetable oils
stuffthe tangible substance that goes into the makeup of a physical object
prototrophA microorganism strain that requires the same nutrients as the wild-type strain.
atomic numberThe number of protons in the nucleus of an atom, unique for each element and designated by a subscript to the left of the elemental symbol.
microspottingA contact-based transfer method that utilizes pins or capillaries to deposit biomolecules on a solid surface.
gel flltrationA chromatographic procedure for the separation of a mixture of molecules on the basis of size; based on the capacity of porous polymers to exclude solutes above a certain size.
hyperglycemiaHigh glucose levels in the blood.
scannerAlso referred to as "reader"; after fluorescent labelling and hybridisation, the scanner or reader scans the microarrays into a computer for subsequent analysis.
aerobic dive limitIn diving mammals and birds, the length of the longest dive that can be undertaken without net accumulation of lactic acid above the resting level.
bootstrapRecalculation of results with randomly rearranged datasets to exclude the possibility of artefacts in data clustering.
fingerprintingA common term for methods that allow the rapid identification of particular types of bacteria (also known as "typing")
conformityA state in which an animal’s internal conditions match the external environmental conditions.
enzymeA protein serving as a catalyst, a chemical agent that changes the rate of a reaction without being consumed by the reaction.
nonmetalselements with varied appearances that do not conduct electricity or heat well
stylusa small, pointed, non-articulated process.
chlorophyllThe pigment in green plants that absorbs solar energy
excitatoryReferring to the effect that a substance has on a nerve cell
periodic tablean orderly arrangement of all the elements based on similarities in their properties
karyogamyA process of fusion of the nuclei of two cells; the second step in syngamy.
scaffoldThe molecular core common to all members of a combinatorial library; also proteins that are instrumental in the assembly of large 3-D structures.
freeunrestricted in movement: not firmly joined with or united to any other part: said of pupae when all the parts and appendages are separately encased as in Coleopteran.
truncaturethe truncation or point squarely cut off.
frontal cortexPart of the brain generally thought to be where higher level thinking, planning, and goal formulation take place.
in situ oligonucleotide synthesisOn-chip synthesis of oligonucleotides or peptide nucleic acids.
n-degronAn N-terminal amino acid sequence that influences the degradation of a protein in which it is found.
pigmentA compound that appears white, black or colored due to the patterns of absorption and reflection of light hitting the molecules of the compound
acneA skin inflammation affecting approximately 80% of those between the ages of 12 and 24
keelan elevated ridge or carina.
particoloredpartly of one, partly of another color: divided into two or more color fields.
fluorescence polarizationThe partial polarization of light emitted from fluorescent molecules.
chapman cycleset of natural steadystate reactions for stratospheric ozone
glycogenA polysaccharide produced by animals for short term energy storage
diploidHaving two different sets of chromosomes in the same nucleus of each cell
chemosyntheticThe synthesis of organic compounds within an organism, with chemical reactions providing the energy source.
endothermAn animal, such as a bird or mammal, that uses metabolic heat to regulate body temperature.
iristhe circle which, in an ocellate spot surrounds the pupil.
optical activityThe property of a molecule that leads to rotation of the plane of polarization of plane-polarized light when the latter is transmitted through the substance
chemotaxisA behavorial response of cells resulting in movement toward or away from to a chemical stimulus.
protoderm(Gr
sampleSubset used to describe a population.
e. coliA small, simple bacteria used in many biology laboratories.
polarReferring to a molecule or structure with a net electric charge or asymmetric distribution of positive and negative charges
intermolecular forceforce that occurs between molecules
micrographThe graphic representation of a microscope image.
batch cultureGrowth of bacteria in a fixed volume of liquid medium in a closed vessel, with no additions or removals made during the period of incubation.
corneaThe transparent frontal portion of the sclera, which admits light into the vertebrate eye.
ultraviolet regionportion of the electromagnetic spectrum that includes wavelengths shorter than those of the visible color of violet
critical loadThe amount of added nutrient, usually nitrogen or phosphorus, that can be absorbed by plants without damaging ecosystem integrity.
standardsA group of reference points with known properties
pla2An abbreviation for Phospholipase A2.
protonA positively charged particle found in the nucleus of an atom
chiral resolutionThe resolution of a mixture of D- and L-enantiomers of a chiral compound.
coutnercurrent exchangeThe opposite flow of adjacent fluids that maximizes transfer ratesEx
biomassThe mass of material produced by living micoorganisms, plants, or animals.
principal component analysisVisual and numerical analysis of collinearity among variables
reactive nitrogencompounds of nitrogen that are biologically active, chemically active, or active with light in our atmosphere
free radicalunstable chemical species with one or more unpaired electrons
solutionhomogeneous mixture of uniform composition
resolutionThe minimum distance that can be distinguished by an optical apparatus; also called resolving power.
protein crystallizationMaking crystals of a protein, as a key part of most methods used for determining a protein's three-dimensional structure.
temperature gradientTechnically, the difference in temperature between two places divided by the distance separating those two places
secondary pollutantpollutant produced from chemical reactions among two or more other pollutants
differential centrifugationSeparation of cell organelles or other particles of different size by their different rates of sedimentation in a centrifugal field.
cambrian explosionA burst of evolutionary origins when most of the major body plans of animals appeared in a relatively brief time in geologic history; recorded in the fossil record about 542-525 million years ago.
celastrolA natural molecule derived from the celastracaeae plant
greenhouse effectThe warming of planet Earth due to the atmospheric accumulation of carbon dioxide, which absorbs reflected infrared radiation and re-refJects some of it back toward Earth.
3′ transductionTransfer of a segment of genomic DNA from one place to another caused by movement of a LINE element.
furculaa forked process: an osmaterium {Scanner's comment: sic
hydrogen bondA weak electrostatic bond which arises from the attraction between the slight positive charge on a hydrogen atom and a slight negative charge on a nearby oxygen or nitrogen atom.
celsius scaleA temperature scale (OC) equal to 5/9 (OF - 32) that measures the freezing point of water at O°C and the boiling point of water at 100°C.
surface tensionThe tendency of water to behave is if it is covered by a semi-rigid film.
molecular biologistA person who studies the molecular life sciences.
ascitesAn accumulation of fluid in the peritoneal cavity
normalizerUsed in both absolute and relative quantification studies to normalize quantitative results of test samples in such a way that the data becomes biologically meaningful.
autoregulationSee autogenous regulation.
cd arrayA microfluidics-based array in compact disc format that utilizes centrifugal force to transport molecules through microchannels.
femtomoleOne quadrillionth mole; 1015.
flowerCollection of reproductive structures found in flowering plants
scaffolding proteinsProteins which facilitate the assembly of a cell structure but are not included in the final structure
angstromA unit of measure used to measure inter-atomic distances within molecules equal to 10-10 meter.
biosensorDevice in which recognition systems of biological chemicals are coupled to microelectronics to allow the low-level detection of substances such as proteins etc
direct measurementA measurement procedure that quantifies a property by measuring exactly what the definition of the property specifies
dexamethasoneA glucocorticoid drug with high glucocorticoid activity and low mineralocorticoid activity that is therefore relatively safe to use in high doses.
deterrenceThe degree to which a plant defense is able to reduce damage during a choice test (in which a natural enemy is able to choose between defended and undefended plants).
molar solutionOne mole of solute dissolved in water to give a total volume of 1,000 mL.
biomeAn ecological community of organisms and environments.
french paradoxThe finding that the rate of heart disease in France is lower than observed in other industrialized countries, despite the fact that the country's diet is rich in saturated fats.
supramaximal exerciseExercise that requires ATP at a greater rate than it can be made aerobically even when an individual’s rate of O2 consumption is maximized.
librarya collection of clones
electrophoresisSeparation of molecules on the basis of their net electrical charge.
hydrolysisThe rupture of a chemical bond by a reaction that involves water.
coagulateto congeal; to change from a fluid to a jelly.
polliniaA mass of fused pollen produced by many orchids.
encephalomyopathy lactic acidosisAnother term for MELAS.
freezing pointThe highest temperature at which a liquid can turn to a solid and freeze
habitatThe physical environment (i.e., the chemical resources and physical conditions) of an organism or organisms.
hindgut fermenterAn animal that has a specialized hindgut chamber housing communities of fermenting microbes that assist with the breakdown of food materials and that often provide biosynthetic capabilities the animal lacks.
littoral zoneIn a lake, the shallow, well-lit waters close to shore.
groupvertical column in the periodic table
polymeraseAn enzyme that catalyzes the synthesis of a polymer from monomers.
climateThe prevailing weather conditions at a locality
inflammationThe immediate defense of tissue against infection or injury.
radiationThe emission of electromagnetic waves by all objects warmer than absolute zero.
transition zoneis the transcontinental belt in which the austral and boreal elements overlap: it is divided into a humid or Alleghanian area; a western arid area; and a Pacific Coast humid area: all of which see.
mitochondriaEnergy-producing structures within cells
pupilThe opening in the iris, which admits light into the interior of the vertebrate eye
probabilityLikelihood of a particular event occurring; more formally, the number of times a particular event occurs divided by the number of all possible outcomes
deconvolutionAn algorithm-based method for eliminating noise and improving the resolution of digital data
argillaceousof the texture, appearance or color of clay.
upregulationAn upward shift in the catalytic activity of an enzyme, the rate of functioning of a biochemical pathway, or the rate of some other similar process brought about in a controlled manner by a regulatory system.
mid-ocean gyresLarge areas in the center of the oceans where nutrients are scarce, resulting in "marine deserts."
photic zoneRegion of the ocean through which light penetrates; and the place where photosynthetic marine organisms live.
orientalin geographical zoology as used by Wallace, that part of the earth's surface including Asia east of the Indus River, south of the Himalayas and the Yangtse-kiang watershed, Ceylon, Sumatra, Java and the Philippines.
bufferA conjugate acid-base pair that is capable of resisting changes in pH when acid or base is added to the system
coenzyme q10Also called ubiquinone, or CoQ10
homocysteineA sulfur containing amino acid
molecular massThe sum of the masses of all the atoms in a molecule; sometimes called molecular weight.
enzymeA biological catalyst
palindromic sequenceA double-stranded DNA sequence with a two-fold rotational axis of symmetry (dyad symmetry).
isotonicHaving the same solute concentration as another solution.
atomic nucleusAn atom's central core, containing protons and neutrons.
3-hydroxykynureninA free radical generator that is present in increased amounts in humans with HD and HD mice.
coefficient of coincidenceRatio of observed double crossovers to expected double crossovers.
marineRefers to the ocean.
fluorescenceEmission of light by excited molecules as they revert to the ground state.
bradykinesiadifficulty initiating and continuing movements; literally means slow moving
spent nuclear fuelradioactive material remaining in fuel rods after they have been used to generate power in a nuclear reactor
intramolecular forceforce that exists within a molecule
protein targetingThe process by which newly synthesized proteins are sorted and transported to their proper locations in the cell.
corneousof a horny or chitinous substance; resembling horn in texture.
steric interferenceInterrupts a biochemical process by physically preventing the process from occurring.
pelagicinhabiting the sea, far from land.
valenceThe bonding capacity of an atom, generally equal to the number of unpaired electrons in the atom's outermost shell.
estsee Expressed sequence tag
ligationThe formation of a phosphodiester bond between two adjacent bases separated by a single-strand break
constitutive enzymesEnzymes required at all times by a cell and present at some constant level; for example, many enzymes of the central metabolic pathways
anodeThe positive electrode of an electrophoretic system toward which anions migrate.
heat shockstress upon the cell resulting from temperatures outside its tolerable range
amitriptylineAmitriptyline hydrochloride is an antidepressant drug
daltonA measure of mass for atoms and subatomic particles.
x-ray diffractionThe diffraction of X-rays that occurs during passage through a crystal.
glutathioneA water-soluble antioxidant, antitoxin, and enzyme co-factor found in animals, plants, and microorganisms
hypothesisA concept or idea that can be falsified by various scientific methods.
essentialismThe philosophical view that all members of a class of objects (such as a species) share certain invariant, unchanging properties that distinguish them from other classes.
tremorA quivering, involuntary movement of a part or parts of the body.
svedbergA unit of measure of the rate at which a particle sediments in a centrifugal field.
toxicityintrinsic health hazard of a substance
electrosprayA method for generating a fine spray of highly charged droplets.
homochronic heredityinheritance at corresponding periods of life.
water-solubleCapable of being dissolved in water.
wet labRefers to experiments performed at the lab bench.
amyotrophic lateral sclerosisA progressive and fatal disorder affecting nerve cells that involves overactivation of glutamate receptors.
icosahedral symmetryThe symmetry displayed by a regular polyhedron that is composed of 20 equilateral triangular faces with 12 corners.
dispersalIn population biology, movement of individual organisms to different localities; in biogeography, extension of the geographic range of a species by movement of individuals.
half-lifeThe time required for the disappearance of one half of a substance.
micrograma millionth (10-6) of a gram
cryptotopeAn immunological determinant that is hidden.
regulationThe maintenance of internal conditions at an approximately constant level while external conditions vary.
phA measure of the acidity or alkalinity of a solution defined as the negative logarithm of the hydrogen ion concentration in moles per liter: pH=−log [H+]
filter feedingFeeding on objects suspended in water that are very small by comparison to the feeding animal, when the mechanism of food collection is some sort of sieving
amino acid residueamino acid that was once incorporated into a peptide chain
desertA terrestrial biome characterized by very low precipitation.
molecular compoundsA substance formed when two or more non-metal molecules combine
humoralContained in a bodily fluid.
dyskinesiaAn impairment in voluntary movement ability.
diauxic growthBiphasic growth on a mixture of two carbon sources in which one carbon source is used up before the other one
evaporationA change in the physical state of a compound from a liquid to a gas; most commonly used to refer to water
inoculumThe initial sample of a microorganism added to a medium used to start a new culture.
sucessionThe predictable change that occurs to assemblages in the context of a natural disturbance regimen.
glucocorticoid-glucocorticoid receptor complexAnother term for the glucocorticoid-GR complex.
dysplasiaAn early stage of carcinogenesis characterized by changes in epithelial morphology.
absorption coefficientThe dissolved concentration of a gas when the partial pressure of that gas in solution is 1 atm
temperature coefficientThe ratio of the rate of a process at one body temperature over the rate of the same process at a body temperature 10°C lower
countercurrent exchangeThe opposite flow of adjacent fluids that maximizes transfer rates; for example, blood in the gills flows in the opposite direction in which water passes over the gills, maximizing oxygen uptake and carbon dioxide loss,
circularround like a circle.
placeboAny intentionally ineffective medical treatment, such as a sugar pill, used to replace medication
anion-exchange resinA polymeric resin with fixed cationic groups; used in the chromatographic separation of anions.
transaminasesSee aminotransferases.
epaAbbreviation for eicosapentaenoic acid.
eicosanoidAny fatty acid with 20 carbons.
inequala surface with irregular elevations and depressions.
lateritiusyellowish-red; yellowish brick color [pale clay yellow with a little red].
melangeA body of rocks consisting of large blocks (mappable size) of different rocks jumbled together with little continuity of contacts.
blast cellAn undifferentiated embryonic cell.
homeostasisA state of balance in the body maintained by several complex biological mechanisms that operate to offset disruptive changes.
energyClassically, energy is defined as the capacity to do work which doesn’t really tell us what it is just what we can do with it if we had some
radiometric datingA method paleontologists use for determining the ages of rocks and fossils on a scale of absolute time, based on the half-life of radioactive isotopes.
electrophoresisThe movement of charged particles through a fluid following the application of an electric field.
false positivesAlso known as Type 1 errors, occur when we observe a difference that in truth is not actually there
hydrogenationA process that alters the chemical structure of unsaturated fat and makes it more solid and long-lasting.
kinetic energyThe energy of motion, which is directly related to the speed of that motion
diploidA full set of genetic material, consisting of paired 
isoelectric pointThe pH of a solution in which a protein has no net charge and does not migrate in an electric field.
prismaticformed like a prism: a play of colors similar to that produced through a prism.
atomic numbernumber of protons in an atom of that element
bifurcationa forking or division into two: the point at which a forking occurs.
cftrsee cystic fibrosis transmembrane conductance regulator.
endochoriumthe layer of the allantois that lines the chorium; the inner layer of the chorium.
enrichmentA condition which increases the proportion of a particular organism or mutant strain from a mixed population
single molecule detectionObservations of the dynamics of single molecules
gel shift assayAlso known as gel retardation assay or gel mobility shift assay
calorieThe amount of heat required to raise the temperature of 1.0 g of water from 14.5 to 15.5 °
x-ray diffractionThe scattering of x-rays from a crystal, resulting in an interference pattern used to determine the structure of the crystal.
aldoseA simple sugar in which the carbonyl carbon atom is an aldehyde; that is, the carbonyl carbon is at one end of the carbon chain.
exothermicterm applied to any chemical or physical change accompanied by the release of heat
pejus temperaturesIn the study of poikilotherms, a range of body temperatures in which animal performance deteriorates as body temperature is gradually raised (upper pejus range) or lowered (lower pejus range)
x-ray crystallographyMost commonly used technique for determining the three-dimensional structure of macromolecules (particularly proteins and nucleic acids) by passing x-rays through a crystal of the purified molecules and analyzing the diffraction pattern of discrete spots that results.
rootUsually the below ground portion of a plant
facial quadranglein bees; the quadrangle bounded laterally by the eyes, above by a line between their summits and below by a similar line between their lowest points.
chemical genomicsThe large-scale study of biological processes based on small-molecule intervention.
redox reactionSee oxidation-reduction reaction.
retinathat portion of the eye upon which the image is formed.
optimal dosageThe dosage that would be best for the patient population at large
two-hybrid systemA method for studying protein-protein interactions
bionicsThe use of information derived from living systems to build electromechanical systems.
moiSee Multipilicity Of Infection.
seedA structure produced by seed plants which encapsulates the embryo
variable expressionVariable extent and intensity of phenotypic signs among people with a given genotype
nonpolara nonpolar molecule does not have a separation of positive and negative electric charges within the molecule
maintenance methylationAddition of methyl groups to positions on newly synthesized DNA strands that correspond with the positions of methylation on the parent strand.
chloroplastAn organelle found only in plants and photosynthetic protists that absorbs sunlight and uses it to drive the synthesis of organic compounds from carbon dioxide and water.
municipal solid wastegarbage, that is, everything you discard or throw into your trash, including food scraps, grass clippings, and old appliances
sahaAbbreviation for suberoylanilide hydroxamic acid.
ataxiaLoss of motor coordination.
adventitiousA term describing any plant organ that grows in an atypical location, such as roots growing from stems.
sonicationA procedure that uses ultrasound to cause random breaks in DNA molecules.
simulationAn emulation of biological systems with predictive value for research; a virtual biological system.
ninhydrin reaetionA color reaction given by amino acids and peptides on heating with ninhydrin; widely used for their detection and estimation.
toleranceThe range of particular environmental factors (e.g
punctuated equilibriumThe occurrence of speciation events in bursts, separated by long intervals of species stability.
rangeA set of values that a number can have
verbal modelA logical model with the relationships between variables expressed in words rather than mathematical equations.
micronA unit of length equal to 10-6 meter.
equalof the same length, size or shape: the superfices when they are without inequalities.
daltonA unit of molecular mass approximately equal to the mass of a hydrogen atom.
molarityA common measure of solute concentration, referring to the number of moles of solute per liter of solution.
chromatographyA process in which complex mixtures of molecules are separated by many repeated partitionings between a flowing (mobile) phase and a stationary phase.
optimumThe value of some variable or set of variables at which some process works best at
rarefactionMonte Carlo resampling approach to develop a curve to identify and allow comparisons among samples using the minimum sample size of all the collections.
electromagnetic spectrumcontinuum of waves ranging from very long and low-energy radio waves to very short and high-energy X-rays and gamma rays
herbivoreAnimal adapted to eat plants.
decomposerAny of the saprobic fungi and prokaryotes that absorb nutrients from nonliving organic material such as corpses, fallen plant material, and the wastes of living organisms, and convert them into inorganic forms.
disulfide bridgeA strong covalent bond formed when the sulfur of one cysteine monomer bonds to the sulfur of another cysteine monomer.
dipoleA separation of charge within a single molecule.
phA measure of how acidic or basic a solution is
optimizationThe process by which a chemical compound is modified by chemical or biological means to make it interact more effectively with the biological target.
persistenceAbility of an organism to remain in a particular setting for a period of time after it is introduced.
power densityenergy capacity per unit of fuel cell mass
dark reactionsReactions that can occur in the dark, in a process that is usually associated with light, such as the dark reactions of photosynthesis.
temperatureproperty of matter that determines the direction of heat flow
auroreous -eusred, like the aurora borealis [crimson lake].
background radiationthe radiation, on average, that exists at a particular location, usually due to natural sources
positive feedbackA physiological control mechanism in which a change in some variable triggers mechanisms that amplify the change.
truncationTo shorten
patentA property right granted by the government of the United States of America to an inventor .to exclude others from making, using, offering for sale, or selling the invention throughout the United States or importing the invention into the United States
multiplex assayA procedure for the parallel analysis of pooled samples.
plasmathe liquid portion of animal fluids and cells.
heterozygosityIn a population, the proportion of loci at which a randomly chosen individual is heterozygous, on average.
carbanionA negatively charged carbon atom.
structure–activity relationship studysystematic changes made to a drug molecule and assessment of the resulting changes in activity
length constantThe distance along a cell over which a change in passively spreading electrical potential decays in amplitude to 37% of its amplitude at the origin.
greenhouse gasesthose gases capable of absorbing and re-emitting infrared radiation
photonA discrete packet or quantum of light energy
meselson–stahl experimentThe experiment which showed that cellular DNA replication occurs by the semiconservative process.
microfibrilA fibril identifiable only by electron microscopy.
secondary structureFor proteins refers to that aspect of a proteins three dimensional structure which is due to the geometry of amino acid bonding between adjacent amino acids and short range hydrogen bonding
topoisomerMacromolecular isomers that differ in topology.
chemostatDevice for maintaining a bacterial population in the exponential growth phase by controlling nutrient input and cell removal.
thermostableAble to withstand high temperatures.
hydrogen ionA single proton with a charge of 1+
parameterA value or constant pertaining to an entire population
cephalonIn trilobites, the head shield bearing the eyes, antennae, and mouth
neutronelectrically neutral subatomic particle with the same mass as a proton
herbGenerally any plant which does not produce wood, and is therefore not as large as a tree or shrub, is considered to be an herb.
leaky mutantA mutant gene that gives rise to a product with a detectable Ievel of biological activity.
photonsindividual bundles of energy
optical activityThe capacity of a substance to rotate the plane of plane-polarized light.
adhdAttention Deficit Hyperactive Disorder, is a neurological disorder initially appearing in childhood with symptoms such as hyperactivity, forgetfulness, poor impulse control, and distractibility.
surface plasmon resonoanceThis occurs when surface plasmon waves are excited by light deflection at a metal.liquid interface
smootha surface without elevations or indentations.
breeder reactora nuclear reactor that can produce more fissionable fuel (usually Pu-239) than it consumes (usually U-235)
ionatom or group of atoms that has acquired a net electrical charge as a result of gaining or losing one or more electrons
upsAbbreviation for ubiquitin-proteasome system.
molean Avogadro's number of objects
solid phase extractionA sample purification method based on the affinity of either the desired or undesired components of a reaction mixture for a solid material and subsequent filtration of the solid material from the reaction.
hydrolysisReaction in which a covalent bond is cleaved with addition of an H from water to one product of the cleavage and of an OH from water to the other.
biomemsThe application of microelectromechanical systems (MEMS) to micro- and nanosystems for genomics, proteomics, and drug delivery analysis; molecular assembly; tissue engineering; biosensor development; and nanoscale imaging.
egb 761A particular extract of Gingko biloba used in Europe to alleviate symptoms associated with several cognitive disorders.
litterThe undecomposed plant and animal material found on the forest floor.
riparianalong the river or along shore.
blue geneA massively parallel supercomputer with 1 million processors that is under construction and will be capable of 1 petaflop floating point operations/sec
b2A cross in which an F1 or F1' individual is mated to one of its parents (P2) or to another individual that is genetically identical to one of its parents.
langmuir-blodgett filmA lipid bilayer on the surface of water.
transcriptionThe synthesis of an 
spectroscopyThe study of molecular or atomic structure of a substance by observation of its interaction with electromagnetic radiation.
membranaceousthin, skin-like, semi-transparent, like parchment: of a thin, pliable texture.
pyrogeographyThe geography of fire, at various scales.
ketoneA functional group of an organic compound in which a carbon atom is double-bonded to an oxygen
trisomy 18Presence of three copies of chromosome 18; in humans, results in Edward syndrome.
energyThe capacity to do work (to move matter against an opposing force).
mediastinalrelating to the longitudinal median line or area.
hippocampusA part of the brain that plays a role in the establishment of new memories.
denitrificationprocess of converting nitrate ions, typically in soil, to nitrogen gas
cuspidateprickly pointed; ending in a sharp point; with an acuminated point ending in a bristle.
anaphylactic shockAn acute, whole-body, life-threatening, allergic response.
prednisoloneSimilar to prednisone in its high glucocorticoid activity
aerobic scope for activityThe differ-ence between an animal’s peak rate of O2 consumption during locomotion and its resting rate of O2 consumption
catalystA compound that lowers the activation energy of a reaction without itself being consumed.
pterygotewing bearing.
contact chemoreceptorA chemo-sensory cell (of a terrestrial animal) that is normally stimulated by chemicals that contact it in a liquid
stasisAbsence of evolutionary change in one or more characters for some period of evolutionary time.
radunit of radiation that indicates absorption of 0.01 J of radiant energy per kilogram of tissue
fatty acid moleculemolecule with two structural features: a nonpolar long hydrocarbon chain generally containing an even number of carbon atoms (typically 12 to 24) and a polar carboxylic acid group at the end of the chain
aridApplied to regions in which the normal rainfall is insufficient to produce ordinary farm crops without irrigation, and in which desert conditions prevail: see humid.
photolithographySelective masking generates light patterns that direct chemical transformations to specific areas of photosensitive surfaces
conditional mutantA mutant that can grow under one set (permissive) of environmental conditions but cannot grow under different (restrictive or nonpermissive) conditions
etherA molecule containing two carbons linked by an oxygen atom.
hypersensitive responseA rapid plant programmed cell death that is orchestrated in and surrounding the initial site of plant pathogen entry that is typically associated with the activation of disease resistance.
stelocyttaressocial wasps in which the comb layers of the nest are supported by pillars and not connected with the envelope: see poecilocyttares and phragmocyttares.
vultusface: that part of head below front and between the eyes.
sibsAn abbreviation for siblings.
biosorptionThe sequestering of chemicals by a biological system.
macromoleculesmolecules of high molecular mass that have characteristic properties because of their large size
multipotentThe ability to give rise to a number of limited cell types.
atomic massaverage mass of an atom of an element compared with an atomic mass of exactly 12 amu for carbon-12 121; mass (in grams) of the same number of atoms found in exactly 12 g of carbon-12
osmoregulationHow organisms regulate solute concentrations and balance the gain and loss of water
knockinAn alteration of a gene in a way that results in a gain of function.
evaporative coolingThe property of a liquid whereby the surface becomes cooler during evaporation, owing to a loss of highly kinetic molecules to the gaseous state
q10 factorThe factor by which the reaction increases when you raise temperature by 10 degrees centigrade (or Kelvin).
half-lifeThe time that it takes for half of the activity of a molecule to decay.
tricuspidateending in three points: with three cusps or teeth.
biosensorA device that uses a biological element, such as an immobilized enzyme or cell, as a sensor.
estsee Expressed sequence tag.
evapotranspirationThe evaporation of water from soil plus the transpiration of water from plants
theory of island biogeographyPredicts that larger, less isolated islands will contain more species than smaller, more isolated islands; that the number of species on any island reflects a balance between the rate at which new species colonize it and the rate at which populations of established species become extinct
ultraviolet radiationThe part of the invivible electromagnetic spectrum (just below violet) with wavelengths between about 100-400 nm.
chemical equilibriumIn a reversible chemical reaction, the point at which the rate of the forward reaction equals the rate of the reverse reaction.
svedberg unitThe unit used to express the sedimentation constant (S = 10-l3 sec)
hydrochlorofluorocarbonscompounds of hydrogen, chlorine, fluorine, and carbon
empiric risksrisks calculated from survey data rather than from genetic theory
stressThe effects of psychosocial and environmental factors on physical and mental well-being.
optical biosensorA sensor that uses light to detect the effect of a chemical on a biological system.
eutrophic lakeA nutrient-rich and oxygenpoor lake, having a high rate of biological productivity
patentA government-issued document that assigns the holder the exclusive right - for a defined period of time - to manufacture, use or sell an invention.
pdcSee pyruvate dehydrogenase complex.
gene symbolThe acronym or abbreviation corresponding to a given gene name
carboxyl groupThe acidic -COOH functional group found in organic molecules.
ischemiaAn inadequate flow of oxygen (hypoxia) due to insufficient blood supply.
photosynthesisComplex series of reactions occurring in some bacteria and plant chloroplasts whereby light energy is used to generate carbohydrates from CO2, usually with the consumption of H2O and evolution of O2.
r&d pipelineSee research and development
vitamin b3Another term for nicotinamide.
array synthesisA form of parallel synthesis used in combinatorial chemistry in which the reactions take place in a spatially organized array.
cloned animalsMultiple genetically identical animals generated by reproductive cloning techniques.
eous or -eusas a suffix, indicates the possession of the quality of the stem word: e.g
arousal thresholdIn the study of sleep, a measure of the difficulty of waking a sleeping individual at a particular time; a low threshold signifies that sleep terminates relatively easily.
pigmentsMolecules that are coloured by the light they absorb
tandem repeatDirect repeats that are adjacent to each other.
confidence intervalA statistical range with a given probability associated with it
hemeA compound made mostly of iron.
radiotelemetryThe use of a radio transmitter placed in or on an animal to transmit data on physiological or behavioral variables.
frequencyUsually used to mean proportion (e.g., the frequency of an allele is the proportion of gene copies having that allelic state).
capacitorTwo conducting plates separated by an insulating layer
pupilthe central mark of an ocellate spot.
homogeneousof the same kind or nature: similar in texture or parts.
hdacAbbreviation for histone deacetylase.
hydrophobicA property meaning "water fearing," describing molecules that are repelled by water.
wave of advanceA hypothesis which holds that the spread of agriculture into Europe was accompanied by a large-scale movement of human populations.
ionAn atom or molecule with a positive or negative electrical charge
epicenterPoint on the Earth's surface directly above the focus of an earthquake.
detergentAn agent that reduces the surface tension of a liquid
signatureAn alternative term for motif or pattern.
protonpositively charged subatomic particle having the same mass as a neutron
solutesubstance that dissolves in a solvent
negative feedbackA process by which the deviations of a property from a specific set-point level are opposed, thereby tending to keep the property at the set-point level.
productivityThe amount of product that is produced within a given period of time from a specified quantity of resource.
nonessential amino acidAn amino acid that may be synthesized by a cell or organism from simple chemical precursors
seleniumA mineral essential to the mammalian diet and the central element in glutathione peroxidase (GPx)
coxAbbreviation for cyclooxygenase.
chronicLong term or frequently recurring
massively parallel computingHigh-performance computing based on the development of parallel processing algorithms and applications that can be executed simultaneously by many separate processors.
stress-induced proteinsMolecules, including heat-shock proteins, that are produced within cells in response to exposure to marked increases in temperature and to other forms of severe stress, such as toxins, rapid pH changes, and viral infections.
tundraA biome at the extreme limits of plant growth
atomic massThe total mass of an atom, which is the mass in grams of one mole of the atom.
fuscous -usdark brown, approaching black; a plain mixture of black and red [crimson lake + black].
actual evapotranspirationThe amount of water annually transpired by plants and evaporated from a landscape, usually measured in millimeters.
mean squareThe sums of squares divided by the degrees of freedom (n
light reactionsThe reactions of photosynthesis that require light and cannot occur in the dark; also known as the light-dependent reactions.
general acid-base catalysisCatalysis involving proton transfer(s) to or from a molecule other than water.
biometricsThe statistical study of biological events.
acetalThe product formed by the successive condensation of two alcohols with a single aldehyde
background extinctionA long-prevailing rate at which taxa become extinct, in contrast to the highly elevated rates that characterize mass extinction.
halophileOrganism which lives in areas of high salt concentration
isotonicReferring to a solution whose solute concentration is such that it causes no net movement of water in or out of cells.
groundwaterWater found underground as a result of rainfall, ice and snow melt, submerged rivers, lakes, and springs
catastrophismThe hypothesis by Georges Cuvier that each boundary between strata corresponded in time to a catastrophe, such as a flood or drought, that had destroyed many of the species living there at that time.
density-gradient centrifugationThe separation, by centrifugation, of molecules according to their density, in a gradient varying in solute concentration.
octet rulethe generalization that electrons in many molecules are arranged so that every atom (except hydrogen) shares in eight electrons
pm10particulate matter with an average diameter of 10 µm or less (on the order of 0.0004 in)
one-step growth curveA plot of the production of lytic growth of a virus vs time
protoplasmA general term referring to the entire contents of a living cell.
auto-A prefix that indicates self-origin.
pesticideA toxic chemical product that kills harmful organisms (e.g., insecticides, fungicide, weedicides, rodenticides).
chemical markup languageA computional language for the management of chemical data.
dimerStructure resulting from the association of two subunits.
phase changeA shift from one developmental phase to another.
genomeThe full set of genetic material of an organism.
magnetic resonance imagingAn imaging technique that produces cross-sectional images for medical research
saturated fatty acidA fatty acid with no double bonds between the carbon atoms of its hydrocarbon chain.
penisThe copulatory structure of male mammals.
savannaA tropical grassland biome with scattered individual trees, large herbivores, and three distinct seasons based primarily on rainfall, maintained by occasional fires and drought.
isomersmolecules with the same chemical formula (same number and kinds of atoms), but with different structures and properties