concomitant administration drug interactions tricyclic antidepressants drug interaction prothrombin time plasma concentrations plasma levels clinical trials oral contraceptives test interactions concurrent administration clinical significance serum levels renal function increased risk adverse effects adverse events cns depressants thiazide diuretics mao inhibitors johns wort blood levels tubular secretion drug-laboratory test interactions dosage adjustment oxidase inhibitors monoamine oxidase inhibitors concomitant therapy blocking agents channel blockers calcium channel blockers single dose plasma concentration laboratory tests additive effects serum concentrations active metabolite dose adjustment side effects renal clearance anti-inflammatory agents muscle relaxants lithium toxicity anti-inflammatory drugs macrolide antibiotics ace inhibitors oral anticoagulants normal volunteers grapefruit juice protease inhibitors concomitant medications concomitant treatment pharmacokinetic interactions interaction study adverse reactions monoamine oxidase antihypertensive effect close monitoring false-positive reaction urinary excretion liver microsomes serotonin reuptake inhibitors reuptake inhibitors prostaglandin synthesis digoxin levels cardiac glycosides systemic exposure selective serotonin reuptake inhibitors dosage adjustments cardiac arrhythmias nonsteroidal anti-inflammatory agents potent inhibitor hypoglycemic agents pharmacokinetic interaction hepatic metabolism diabetic patients potassium-sparing diuretics enzyme system renal excretion human liver microsomes prothrombin times pediatric powder valproic acid potent cyp clinical pharmacology cns depression nonsteroidal anti-inflammatory drugs protein binding beta-adrenergic blocking agents narcotic analgesics reductase inhibitors clinical relevance pharmacokinetics of digoxin blood glucose concurrent therapy renal tubular secretion respiratory depression local anesthetics hmg-coa reductase inhibitors multiple doses severe hypoglycemia recommended dose binding sites central nervous system depressants hypotensive effect dose reduction risk of lithium toxicity clinical laboratory tests nicotinic acid normal subjects acetylsalicylic acid years of age system depressants concentration-time curve extreme caution elimination half-life metabolism of caffeine male volunteers myocardial infarction aminoglycoside antibiotics platelet function serum potassium combination therapy vitro data azole antifungals postural hypotension diabetes mellitus metabolic clearance auc values degree of inhibition clinitest tablets chewable-buffered tablets repeated challenge potassium supplements hypericum perforatum platelet aggregation marked bradycardia receptor antagonists risk of bleeding ventricular arrhythmias volume of distribution increased incidence debrisoquin hydroxylase qt interval enzyme inducers tricyclic antidepressant crossover study anticoagulant dosage anticholinergic activity body weight calcium antagonists gastrointestinal absorption fehlings solution rare reports impaired renal function function tests anaphylactic reaction renal insufficiency normal metabolizers mean cmax diuretic therapy reliable estimates intestinal absorption package insert acid secretion oral contraceptive extent of absorption inhibitor of p thyroid products doses of epinephrine dose-dependent manner adjustment of dosage glucose tolerance monitoring of patients sufficient time thyroid hormone initiation of treatment renal prostaglandin synthesis breakthrough bleeding potent inducer case reports literature reports coumarin anticoagulants neuromuscular blockade neuromuscular block close supervision post-marketing experience long half-life insulin requirements excessive reduction oral hypoglycemics extent of inhibition salt intake loop diuretics reduction of bloodpressure peripheral vasospasm orthostatic hypotension medicinal products patient monitoring allergic reaction cerebrovascular accidents skeletal muscle relaxants pharmacokinetic parameters ischemic heart disease digitalis glycosides asa result soluble vitamins pump inhibitors mechanism of action catecholamine depletor cardiovascular disease rate of absorption myasthenia gravis therapeutic range therapeutic index hepatic enzyme inducers enzyme systems calcium supplements pharmacodynamics of warfarin inhibitor of cytochrome p veratrum alkaloids mean auc artery disease blocking action coronary artery disease hypoglycemic action lithium carbonate rheumatoid arthritis male rats salt substitutes trivalent cations aluminum hydroxide antiarrhythmics propafenone menstrual irregularities elevated tbg caucasian population loss of control evidence of hypotension vital signs eight-fold increase magnesium hydroxide cephalosporin antibiotics female volunteers hormonal contraceptives benedicts solution resin uptake washout period qtc interval digitalis preparations potassium loss vasospastic reactions magnesium salts release of norepinephrine hepatic impairment wistar rats secretion of methotrexate opioid analgesics severe anaphylactic reaction risk of myopathy ventricular tachycardia qt intervals disease states microsomal enzymes conduction disturbances male subjects intravenous infusion human dose coumarin-type anticoagulants qt prolongation paralytic ileus thyroid-binding globulin cyp enzymes strong cyp neuromuscular blocking action withdrawal symptoms folic acid moderate inhibitor protein-bound iodine mao inhibitor av conduction replacement therapy ethyl alcohol alkaline phosphatase catabolic enzymes metabolism of cisapride demonstrated hypokalemia neuromuscular transmission discontinuation of cimetidine arterial responsiveness tissue culture post-marketing observations prescribing information bleeding complications spontaneous reports sustained increases muscle pain b-lactam antibiotics fasting conditions extensive metabolizers dose-dependent fashion symptoms of schizophrenia platelet count methods of contraception enzymes of vitamin urinary retention gastric emptying adult volunteers calcium-containing preparations magnesium-containing preparations vaginal preparations herbal products transient increases functional antagonism preparations of miconazole rare instances ergot-type medications statistically significant increase incidence of breakthrough bleeding cardiac dysrhythmias medical supervision cardiac output psychotropic medications binding globulin calcium-channel blockers transplant recipients mental status hepatic cytochrome sympathomimetic amines inhaled corticosteroids persistent hypertension co-administration of cimetidine risk of hyperkalemia risk of convulsions human lymphocytes steady-state conditions anesthetic solutions severe peripheral vasospasm positive reaction uncontrolled intake cns stimulation reaction profile iron salts electrocardiographic parameters local anesthetic solutions gradual withdrawal transient elevations inducers of cytochrome p weight gain highly bound coumarin derivatives safety profile phosphate transport abdominal irradiation abdominal symptoms aberration assay abnormal bleeding abnormal handling abnormal laboratory abnormal renal uptake abnormal topoisomerase quantity abnormal vaginal bleeding abortifacient potential abrasive soaps abrupt suppression absence of glibenclamide absence of glucose absence of kidney function absence of probenecid absolute abstinence absolute alcohol absolute number absorption of alendronate absorption of amphetamines absorption of arsenate absorption of chloroquine absorption of chlorothiazide absorption of cimetidine absorption of ciprofloxacin absorption of cobalt absorption of digoxin absorption of dirithromycin absorption of drugs absorption of enoxacin absorption of ethambutol absorption of ethosuximide absorption of fosinopril absorption of hydrochlorothiazide absorption of ibuprofen absorption of iron absorption of ketoprofen absorption of lymecycline absorption of metformin absorption of penicillin absorption of phenobarbital absorption of phenytoin absorption of primidone absorption of quinolones absorption of tetracycline absorption of tetracyclines absorption of vitamin absorption of vitamin k absorption of zalcitabine absorption site abstinence syndrome accelerated prothrombin time acceptable alternatives acceptable tolerability profile accident suicide accidental contact account variations accumbal dopamine accutane prescription accutane therapy ace inhibitor ace inhibitor benazepril ace inhibitor therapy ace-inhibitors reports acetaminophen hepatoxicity acetaminophen o-glucuronidation acetaminophen overdosage acetaminophen tablets acetaminophen toxicity acetohydroxamic acid acetylcholine-induced vasorelaxation acetylcysteine interference acid administration acid antagonists acid concentrations acid derivatives acid diminished binding acid excretion acid hcl acid level acid levels acid metabolism acid metabolite acid phosphate acid precipitation procedure acid reactive substances acid sequestrant acid sequestrants acid supplements acid-base balance acid-catalyzed ethanol-drug reaction acid-catalyzed ethanolysis acidic conditions acidic drugs acidifying agents acinar cells acitretin therapy acitretin treatment acquired behavioral response acquired immunodeficiencies acquisition cost acquisition cost of olanzapine acquisition of tasks acr criteria acth hypertension acth treatment acth treatment of relapses actin microfilaments acting drugs acting nitrates actinic keratoses action potentials activase therapy activated charcoal activated prothrombin activation factor active antiretroviral therapy active carbamazepine active dose active isomer active metabolite concentration active metabolite desmethylastemizole active metabolite desmethylastermizole active metabolite doxorubicinol active metabolite formation active metabolites active organic cationic secretion active phosphorylated zalcitabine active ra active renal tubular secretion active s-isomer active sulindac sulfide metabolite active tubular secretion active vomiting active zalcitabine triphosphate metabolite activity transient cardiac arrhythmias acts asa stimulator acute alcohol intake acute angina attacks acute asthma acute delirium acute dosing acute effect acute episode acute ergot toxicity acute hydrocortisone administration acute hydrocortisone pretreatment acute increase acute indications acute insulin release acute ischemic stroke acute locomotor effects acute myocardial infarction acute myocardial infarction setting acute phase acute phase schizophrenia acute pulmonary toxicity acute symptoms acute toxicity acute toxicity tests acutely injected mice aczone gel adapter protein adaptive value added antiarrhythmic drug added beta-adrenergic blocking action added cholesterol added concentration added drug addiction research centre inventory addictive disease addictive medications addition of carbamazepine addition of diltiazem addition of doxepin addition of ethanol addition of felbamate addition of isradipine addition of lomefloxacin addition of phenytoin addition of tiagabine addition of triamterene addition of valproate additional hour additional iron additive adverse effects additive cns depressant effect additive cns depressant effects additive cns depression additive depressant effect additive depressant effects additive effect additive effector potentiation additive hypotensite effects additive hypotensive effect additive inotropic additive interaction additive negative inotropic effects additive ocular additive pharmacodynamic effect additive pressor effect additive sedative effects additive toxic effects additive toxicity additive vasodilator properties adefovir dipivoxil adenosine antagonists adenosine dosage adenosine effects adenosine receptor antagonists adenosine receptors adenylate cyclase activity adenylyl cyclase desensitization adequate cervical dilatation adequate degree adequate dosage replacement adequate evidence adequate methods adequate monitoring adequate period adequate respiratory exchange adequate treatment adjunctive anticholinesterase dosage adjunctive therapy adenosine dosage adjustment of dosages adjustment of doses theophylline dosage adjustment sections adjuvant trials administered agents administered antibiotics administered anticoagulant agents administered antiepileptic drugs administered aspirin administered botulinumtoxin administered bumetanide administered diltiazem administered dose administered drugs administered famotidine administered labetalol hcl administered leucovorin administered methotrexate administered methylxanthines administering disulfiram administering gleevec administering ibuprofen administering itraconazole administering nabumetone administering nitazoxanide administering peganone administering taxol administration indinavir administration of adrenaline administration of allopurinol administration of alosetron administration of alprazolam tablets administration of aluminum administration of aminoglycoside antibiotics administration of anakinra administration of antacids administration of aprepitant administration of aspirin administration of azathioprine administration of bombesin administration of bosentan administration of bupropion administration of caffeine administration of carbamazepine administration of cefdinir administration of cefepime administration of ceftazidime administration of cephalosporins administration of chlordiazepoxide administration of cimetidine administration of ciprofloxacin administration of cisapride administration of citalopram administration of clarithromycin administration of compounds administration of contrast media administration of coumaphos administration of cypermethrin administration of danazol administration of dantrolene administration of daptomycin administration of dexamethasone administration of diazepam administration of diclofenac administration of diflunisal administration of digoxin administration of diltiazem hydrochloride administration of disulfiram administration of dmpge administration of dopamine administration of doxapram administration of drugs administration of dyphylline administration of ect administration of ellence administration of enoxacin administration of epinephrine administration of eplerenone administration of erythromycin administration of etanercept administration of ethambutol administration of fenofibrate administration of fentayl administration of fluconazole administration of griseofulvin administration of guanfacine administration of haloperidol administration of hydrocodone administration of indigestion remedies administration of indinavir administration of isoniazid administration of ketoconazole administration of ketoconazole tablets administration of lapatinib administration of levorphanol administration of levothyroxine sodium administration of lidocaine administration of lithium administration of lithium prophylaxis administration of lomefloxacin administration of losartan administration of low-dose aspirin administration of low-dose dopamine administration of loxapine administration of macrolide antibiotics administration of magnesium hydroxide administration of methotrexate administration of methylphenidate administration of midazolam administration of naratriptan administration of neuroleptics administration of nicardipine administration of nifedipine administration of non-steroidal administration of norfloxacin administration of omeprazole administration of oxyphenbutazone administration of oxytocin administration of pargyline administration of peptide drugs administration of phenobarbital administration of phenytoin administration of picrotoxin administration of probenecid administration of propoxyphene hydrochloride administration of proton pump inhibitors administration of quinidine administration of quinolones administration of repeat doses administration of reserpine administration of rifampin administration of sonata administration of substrates administration of succinylcholine administration of sucralfate administration of sulfadoxine administration of tablets administration of terfenadine administration of thiazide diuretics administration of thiazides administration of thiosulfate administration of tiagabine administration of vaccines administration of valdecoxib administration of vasopressor drugs administration of verapamil administration of vistide administration of vitamin administration of warfarin administration of zalcitabine administration regimens administration-dosage adjustment sections administrative arrangements adp-induced increases adrenal corticosteroid synthesis adrenal corticosteroids adrenal function tests adrenal insufficiency adrenal reserve adrenal suppression adrenergic agents adrenergic agonists adrenergic antagonists adrenergic beta-receptor blockers adrenergic blockers adrenergic blockers adrenergic adrenergic blocking agents adrenergic blocking drugs adrenergic bronchodilators adrenergic drugs adrenergic effect adrenergic nerve endings adrenergic neuron adrenergic receptor antagonism adrenergic stimulant type adrenergic-blocking agents adreneric agents adrenocortical steroid dependent hypertension adrenocortical steroids adsorption of nitrofurantoin adult data adult diabetics adult patients adult wistar rats adult-onset diabetics advanced hiv disease adverse cardiovascular effects adverse clinical effects adverse clinical experiences adverse consequences adverse drug effects adverse drug events adverse drug interaction adverse drug reaction adverse drug reactions adverse event profile adverse experience profile adverse experiences adverse interactions adverse neuropsychiatric events adverse reaction profile aed aed felbatol coadministered concentration aed co-administered dose aed concentration aed felbatol coadministered concentration aed interactions aerobic bacteria aerolizertm inhalation device aerosol bronchodilators aerosol particles aerosol particles of budesonide aerosolized pentamidine aerospace environment aeruginosa serotype aetiological factor affect abilify aripiprazole affect duloxetine affect gastric acidity affect other drugs aripiprazole affected prothrombin times affecting myelopoesis affecting sympathetic activity affinity chromatography procedure affinity substrates african trypanosomiasis african-american man after cholestyramine resin aftercare approaches age-dependent alterations aged persons agent cholestyramine agent warfarin agents affecting myelopoesis agents affecting sympathetic activity agents anti-migraine antifungal astemizole midazolam agents antiarrhythmics agents causing renin release agents concentration caution agents concentration plasma concentrations agents ethinylestradiol agents highly bound agents ketoconazole agents of class agents rifabutin aggravating myasthenia gravis aggregation inhibitors aggregation response aggregation time aggressive symptomatic therapy agonist drugs agonist effects agonist opioid analgesic agonist-antagonist analgesics agonist-antagonist effects agonist-antagonist opioid analgesics agonists concomitant agonists fentanyl examples air passages albendazole sulfoxide albendazole sulfoxide concentrations albendazole sulfoxide plasma concentrations albino rat albino rats albumin binding alcohol abuse alcohol dehydrogenase inhibition alcohol ingestion alcohol intake alcohol tolerance alcohol usp alcohol's effects alcohol's influence alcohol-related deaths alcoholic beverages aldehyde oxidase aldehyde oxidase enzyme system aldosterone excretion aldosterone production alfenta clearance alfenta doses alfenta induction aliskiren blood levels aliskiren cmax aliskiren exposure alkaline earth alkaline picrate method alkaline urine red-orange alkalinizing agents alkaloid class alkaloid congener alkaloids ergotamine immunosuppressants cyclosporin alkyl esters alkylated androgens allergic reactions allium sativum allograft recipients allopurinol sodium allopurinol toxicity almotriptan clearance alosetron plasma concentrations alpha cell alpha interferons alpha-adrenergic blocking agents alpha-adrenergic stimulants alpha-blocker therapy alprazolam concentrations alprazolam dosage alprazolam metabolism alprazolam tablets alter renal excretion ibuprofen alteration of ph alteration of prothrombin time alterations of blood levels alterations of magnesium status altered biodistribution altered coagulation parameters altered consciousness altered distribution altered mental status altered pharmacoktnetics altered plasma concentrations altered renal function altered responsiveness altered safety altered serum levels altered tsh secretion alternate sequence alternate treatments alternate-day administration alternating therapy alternative agents alternative antihypertensive therapy alternative error structures alternative hypoglycemic agents alternative non-cyp alternative therapeutic agents alternative therapy alternative treatment altretamines half-life aluminum antacids aluminum hydoxide aluminum-containing antacid aluminum-containing antacids aluminum-magnesium hydroxide antacids alveolar concentration amantadine antiarrhythmic agents ambulatory patients amerge tablets american clinical trials american coffee american trials ames bacterial mutagenicity assay ames company ames n-multistix sg dipstick test ames test amiloride hcl amino acid aminocaproic acid aminoglycoside antibiotic aminoglycoside serum half-life aminoglycosidic antibiotics aminosalicylic acid aminotransferase determinations amiodarone administration amiodarone auc amiodarone concentrations amiodarone contraindicated amiodarone increases amiodarone levels amiodarone serum concentration amiodarone serum levels amiodarone therapy amiodarone toxicity amiodarone-treated patients amitriptyline exposure amitriptyline hcl ammonium chloride amphetamine cns stimulation amphetamine metabolism amphetamine molecule amphetamine poisoning amphetamine users amphotericin b-induced hypokalemia ampicillin esters ampicillin increases ampicillin rashes ampicillin toxicity amplitude data amplitudes of components p amprenavir auc amprenavir sustivahas amprenavir's pharmacokinetics amyl nitrite amylase activity amylase assays amylase levels anabolic hormones anabolic steroids anaerobic bacteria anaerobic clinical isolates anaesthesiological fields anaesthetic agents anaesthetised horses anagrelide absorption anakinra therapy analgesic action analgesic actions analgesic adjuvants analgesic drugs analgesic effect analgesic effects analogue d-ala analogue scales analogues didanosine co-administration analysis of side effects analytical procedures anaphylactic reactions anaphylactic shock anastrozole plasma levels androgen concentrations anecdotal reports anesthesia recovery time anesthetic agents anesthetic requirement angina attacks angina myocardial infarction angina patients angina pectoris angiotensin converting enzyme angiotensin ii receptor antagonists angiotensin influence angiotensin-converting enzyme angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors angiotensinogen-renin substrate angiotensln converting enzyme inhibitors anhydrase inhibitor anhydrase inhibitors animal cells animal data animal experience animal literature animal model animal models animal reproduction animal source animal species animal studies wshow animal toxicology anion exchange resin anion plasma levels anion-exchange resins anionic exchange resins anionic transport anionic-binding resin ankle edema anorectic effect anova models antabuse-like side effects antacid components antacid dose antacid preparations antacid products antacid properties antacid suspension antacid therapy antacids administration antagonism opioid analgesics antagonist class antagonist effect antagonistic effect antagonistic effects antagonistic properties anti-apoptotic effect anti-arrhythmic agents anti-asthma medications anti-coagulant effect anti-coagulant effect of warfarin anti-cryptosporidial activity anti-depressants-anti-anxiety drugs anti-estrogenic activity anti-factor xa anti-glaucoma action anti-glaucoma action of carbachol anti-globulin tests anti-helminthic treatment anti-hiv protease inhibitors anti-hiv protease inhibitors indinavir anti-hiv reverse transcriptase inhibitors didanosine anti-hypertensive drug therapy anti-inflammatory action anti-inflammatory activity anti-inflammatory agent anti-inflammatory drug anti-inflammatory drug fenbufen anti-inflammatory drug indomethacin anti-inflammatory therapy anti-ks agents anti-malarial drugs anti-migraine antifungal astemizole midazolam anti-neoplastic agents anti-peptic agents anti-platelet activity anti-platelet activity of low-dose anti-platelet effect valdecoxib anti-ulcer therapy antiaddictive efficacy antiaggregant prostacyclin antianginal effectiveness antianxiety agents antianxiety drugs antiapoptotic effect antiarrhythmic agent antiarrhythmic agents antiarrhythmic agents concentration caution antiarrhythmic drug antiarrhythmic drugs antiarrhythmic therapy antiarrhythmics amiodarone antiarrhythrnics propatenone antiasthmatic dose antibacterial drug levels antibacterial effect antibiotic agents antibiotics-broad-spectrum antibiotics antibody response antibody tests anticancer agents anticancer drugs anticholinergic action anticholinergic actions anticholinergic agent anticholinergic agents anticholinergic compounds anticholinergic drugs anticholinergic effect anticholinergic effects anticholinergic medications anticholinergic pharmacological effects anticholinergic side effects anticholinergic symptoms anticholinergic syndrome anticholinergic-containing drugs anticholinergic-type drugs anticholinesterase agents anticholinesterase dosage anticholinesterase drugs anticholinesterase effect anticholinesterase effect of cholinesterase inhibitors anticholinesterase overdose anticholinesterase poisoning anticholinesterase treatment anticipation of drug interactions anticoagulant action anticoagulant activity anticoagulant agents anticoagulant dose anticoagulant effect anticoagulant effects anticoagulant inhibition anticoagulant interference anticoagulant medication anticoagulant response anticoagulant therapy anticoagulant warfarin anticoagulants altered coagulation parameters anticoagulants caution anticoagulants interaction anticoagulants should be reduced anticoagulation effects anticoagulation effects of heparin anticoagulation levels anticoagulation test anticonvulsant action anticonvulsant agents anticonvulsant drug toxicity anticonvulsant drugs anticonvulsant effect anticonvulsant medications anticonvulsant plasma levels anticonvulsant properties anticonvulsant properties of carbamazepine anticonvulsant therapy anticonvulsants carbamazepine anticonvulsants phenytoin antidepressant activity antidepressant activity transient cardiac arrhythmias antidepressant agent antidepressant agents antidepressant assay antidepressant class antidepressant desipramine antidepressant drugs antidepressant imipramine antidepressant level antidepressant levels antidepressants experienced tremor antidepressants metoprolol antihistamines carbamazepine antidiabetes products antidiabetic agent antidiabetic agents antidiabetic drug antidiabetic drug requirements antidiabetic drugs antidiabetic effect antidiabetic medication antidiabetic products antidiarrheal activity antidiarrheal preparations antidiuretic activity antidiuretic hormone antidotal properties antiedematous action antiemetic prophylaxis antiemetics ondansetron antiepilepsy drugs antiepileptic drugs antiepileptic drugs phenytoin antiepileptic effect antifibrinolytic therapies antifungal activity antifungal agents antifungal agents ketoconazole antifungal astemizole midazolam antifungal drug antiglaucoma agents antigout drugs antigout medications antihistamines antipsychotic agents antihistamines carbamazepine antihistamines terfenadine antihistaminic drugs antihyperglycemic effects antihypertensive action antihypertensive action of guanethidine antihypertensive agents antihypertensive compounds antihypertensive drugs antihypertensive effect of ace-inhibitors antihypertensive effect of beta-adrenoceptor antihypertensive effect of furosemide antihypertensive effect of losartan antihypertensive effect of propranolol antihypertensive effects antihypertensive effects of furosemide antihypertensive effects of loop antihypertensive effects of methyldopa antihypertensive effects of reserpine antihypertensive medications antihypertensive therapy antiinflammatory agent antiinflammatory agents antiinflammatory drug antiinflammatory drugs antimicrobial activity antimicrobial agents antimicrobial combinations antimicrobial effect antimuscarinic effects antimycobacterial agents antimycobacterial agents rifabutin antinaturetic effect antineoplastic agents antineoplastic drugs antinociceptive effect antinonciceptive effect antinuclear phosphokinase antibody antioxidative gallates antiparkinson drugs antiparkinsonian agents antiparkinsonian drug antiparkinsonism agents antiplatelet agents antiplatelet therapies antiprothrombinemic effect antipsychotic action antipsychotic activity antipsychotic agent antipsychotic agents antipsychotic clozapine antipsychotic drug antipsychotic drugs antipsychotic efficacy antipsychotic medications antipsychotic potential antipyrine elimination antipyrine pharmacokinetics antiresistance determinant gene transfer antiretroviral agents antiretroviral drugs antiretroviral effect antiretroviral medication antiretroviral medications antiretroviral nucleoside analogues antiretroviral plasma antiretroviral regimen antiretroviral regimens antiretroviral therapy antiseizure medication antisense gene cassette antisense oligomer antisense rna effect antiseptic effect antistress effects antithrombin iii activity antithrombin iii deficiency antithrombotic agent warfarin antithrombotics aspirin antithrombotics warfarin potential effect antithyroid agents antithyroid drugs antitubercular drugs antituberculosis drug rifampin antituberculous drugs antitumor activity antitumor drugs antitumor effectiveness antitumour activity antiviral activity anxiety-depressive symptoms anxiogenic effects aortic rings apoptotic index apoptotic morphology apparent decrease apparent effect apparent elimination half-life apparent factor concentration apparent increase apparent interaction apparent oral clearance apparent oral clearance values apparent pharmacokinetic interaction apparent total body clearance apparent volume application mode application of glycine application of perchlorate appropriate dosage adjustment appropriate doses approved agents approximate doubling approximately half approximately one-third approximately six months approximately three days apraclonidine withdrawal aprepitant aprepitant aprepitant auc aptt assay aptt prolongation concomitant treatment aqueous ethanol solutions aqueous extract aqueous phase arachidonic acid arachidonic acid metabolism arava levels arbutamine-mediated stress test arc gene arc mrna arc mrna level are mainly metabolized area basis area family area major contributing factor area number argatroban therapy aripiprazole clearance aripiprazole dose aripiprazole elimination aripiprazole metabolism aripiprazole therapy arrest-cardiac arrest arsenate absorption arsenical encephalopathy arsenical reactive encephalopathy arterial hypertension arterial pressure arterial puncture sites arterial thrombus formation artery vasospasm arthritic patients arthritis medication arthritis patients article review papers artocarpus integrifolia as narcotics asa change asa change of lifestyle asa class asa consequence asa false-negative result asa guide asa local factor asa metabolite asa metabolite of furazolidone asa method asa precursor asa separate section asa single daily oral dose asa stimulator asa substitute ascorbic acid asparagine levels aspecific treatments aspergillus eia test aspergillus infection aspirin absorption aspirin effectiveness aspirin increases aspirin therapy aspirin-mediated inhibition aspirin-nonsteroidal antiinflammatory drugs aspirins anti-inflammatory action assay asa method assay methods assay methods toxi-lab assay of serum assay of thio compounds assay result assay system assessment of everolimus assessments of drug-drug interactions association functional class astemizole midazolam asthma control asthma drugs asthma therapy compliance asymptomatic increases asymptomatic liver enzyme elevations atac trial atherosclerotic cardiovascular disease atherosclerotic disease atherosclerotic risk factors atomoxetine steady-state plasma concentrations atorvastatin administration atorvastatin auc atorvastatin cmax values atorvastatin plasma concentrations atovaquone concentrations atoxic effect atoxic level atracurium infusion atrial fibrillation atrioventricular conduction disturbances atrioventricular conduction time atropine sulfate atropine-like effects atropine-type drugs atrovent inhalation aerosol attention test attenuate potassium loss attenuated live bacteria attenuated vaccines attenuation of immunization atypical adverse reactions atypical antipsychotic atypical antipsychotic clozapine atypical neuroleptic clozapine atypical sideeffect auc determinations auc of aprepitant auc of aripiprazole auc of atomoxetine auc of butorphanol auc of caspofungin auc of ciprofloxacin auc of cisapride auc of clonazepam auc of delavirdine auc of desipramine auc of dexamethasone auc of didanosine auc of doxazosin auc of epirubicin auc of ethinylestradiol auc of felodipine auc of midazolam auc of norethindrone auc of tolbutamide auc values of diclofenac aucasian population augmentin xr authorization cards automated equipment automatic behaviour autonomic instability autonomic irritability autonomic neurotoxicity av block av conduction disturbances av nodal conduction av node conduction av nodes availability of digoxin available assay methods toxi-lab average decreases average increase average infusion rate requirement average steady-state plasma atovaquone concentrations aviano cancer centre avoid impeding their absorption avoidance behaviour azithromycin serum concentrations azole antifungal azole antifungal agents b-adrenergic blocking agents b-blocking agent b-blocking drug b-blocking properties b-cell hyperplasia b-cell lymphoma b-cell lymphomas b-induced hypokalemia bacillus subtilis back-up methods background response backwards displacement baclofen injection baclofen tablets bactec radiometric method bactercidal effect bacterial infection bacterial metabolism bacterial mutagenicity assay bacterial mutation assay bactericidal action bactericidal activity bactericidal concentration bactericidal effect bacteriostatic antibiotic bacteriostatic antibiotics bacteriostatic drugs balance technique balance testing balanced technique bar-press behaviour bar-press conditioning bar-press response barpress response barrier contraception barrier form basal colonic fluid contents basal conditions basal plasma cortisol concentration basal plasma renin activity basal small intestinal transits baseline concentrations baseline neutrophil counts baseline phenytoin serum level baseline values basic area basic science be determined on different days be reduced be used with caution behavioral effects behavioral inhibition behavioral mechanisms behavioral response behavioral responses behavioral responsiveness behavioral sensitization belladonna alkaloids beneficial effects benefit of gentamicin benefits of medications benign breast disease benign intracranial hypertension benign ovarian granulosa cell tumors benign prostatic hyperplasia benzodiazepine administration benzodiazepine agonist benzodiazepine class benzodiazepine effect benzodiazepine receptors benzodiazepine treatment benzodiazepines area family benzodiazepines midazolam benzyl alcohol bepridil hydrochloride bepridil therapy beta adrenergic antagonists beta adrenergic blockers beta adrenergic blocking agents beta adrenergic-blocking agents beta blocking agents beta cells beta-adrenergic antagonists beta-adrenergic blockers beta-adrenergic blocking action beta-adrenergic blocking agent beta-adrenergic blocking drug beta-adrenergic blocking drugs beta-adrenergic neuroeffector defects beta-adrenergic receptor beta-adrenergic receptor antagonists beta-adrenergic receptor blockers beta-adrenergic stimulating properties beta-adrenergic-blocking agents beta-adrenergicblocker metoprolol beta-agonist bronchodilator drugs beta-blocker inhibition beta-blocker therapy beta-blocker-mediated reduction beta-blocking agents beta-blocking properties beta-lactam antibiotics beta-lactamtype antibiotics beta-receptor agonist drugs beta-receptor blockers betablockers controlled betaseron administration bexarotene concentrations bexarotene oxidative metabolites bilateral ovariectomy bile acid bile acid sequestrant bile acid sequestrants bile acids bile-acidsequestering agent cholestyramine biliary excretion biliary route bilirubin elevations bilirubin levels bind other drugs given concurrently binding activity binding displacement binding experiments binding lectin binding of acetaminophen binding of fibrinogen binding of ketorolac binding of phenobarbital binding of phenytoin binding of theophylline binding of thyroxine binding proteins binding site binding-based drug interactions binds bile acids bioassay procedures bioavailability of ampicillin bioavailability of anagrelide bioavailability of carbidopa bioavailability of ceftibuten bioavailability of ciprofloxacin bioavailability of cisapride bioavailability of digoxin bioavailability of enoxacin bioavailability of fexofenadine bioavailability of fosinoprilat bioavailability of isoniazid bioavailability of levodopa bioavailability of propranolol bioavailability of trovafloxacin bioavailability of verapamil bioavailability parameters bioavailabillty digoxin biochemical activity biochemical toxicology biocytin inclusion bioequivalence study biogen pregnancy registry biologic half-life biological half-life biological half-lives biological indicators biological levels biological monitoring biopharmaceutical properties biotransformation of tolbutamide biotransformation system bipolar disorder birth control birth control pills birth control products bismuth subsalicylate bivalirudin antibody tests biweekly intervals black cohosh bladder cancer cells bleeding events bleeding international normalized ratio bleeding problems bleeding tendency bleeding time bleeding times block morphine-induced blockade of atracurium blockade of vecuronium blocker diltiazem blocker metoprolol blockers adrenergic blockers concentration caution blockers diltiazem blockers nimodipine blockers-proton pump inhibitors blocking agent blocking drug blocking drugs blocking effects blocking properties blocks dopamine blood assays blood auc blood cell counts blood cells blood cisapride levels blood coagulation blood coagulation ketoprofen blood coagulation system blood concentration blood concentration of tacrolimus blood concentration-time curve blood concentrations blood elements blood flow blood glucose concentrations blood glucose control blood glucose levels blood level blood levels of drugs blood levels of hydrodolasetron blood lipids blood loss blood plasma glucose levels blood platelets blood pressures blood samples blood sampling blood sirolimus area blood sirolimus concentrations blood sugar blood sugar concentrations blood sugar control blood sugar level blood thinners blood uric acid blood-glucose-lowering effect blood-plasma glucose levels blood-sugar levels blood-sugar-reducing effect blood-sugar-reducing effect of insulin bloodpressure control bloodpressure effect bloodpressure medications bloodpressure reaction bloodpressure reductions bloodpressure response blot analysis body clearance body clearance of cisplatin body clearance of digoxin body clearance of levetiracetam body declines body increase body surface area body surface area basis body tremors body weight gain bodys ability bolus doses bolus injections bombesin-enhanced peritoneal metastasis bone density bone marrow depression bone marrow erythrocytes bone marrow function bone marrow megakaryocytes bone marrow suppression bone marrow suppression warrants consideration bone mineral density bone scintigraphy borderline statistical significance boric acid bosentan plasma concentrations botulinum neurotoxin serotypes botulinumtoxin serotypes bound drugs bound ketoprofen bovine chromaffin cell bovine chromaffin cells bovine lung bovine thyroglobulin bowel disease bowel syndrome brain chemical brain edema brain hemorrhage brain levels brain levels of ketamine brain memory system brain sites brain systems breakdown products breakfast cereals breakthrough symptoms breast cancer cell growth breast cancer cells breast cancer recurrence breast disease breast enlargement breast milk breath test bretylium tosylate bretylium tosylate injection brevibloc concentrations brevibloc pharmacokinetics brevibloc steady-state blood levels brief psychiatric rating scale brinzolamide ophthalmic suspension broad-spectrum antibiotics broad-spectrum antibiotics-broad-spectrum antibiotics broadening indications bromocriptine mesylate bronchodilator drugs bronchodilator effect broth dilution method brovana dose brovana doses budesonide administration budesonide dose buffalo hump buffered tablets buffering effects bullous pemphigoid bumetanide natriuresis bumetanide treatment bumetanide-induced increase buspirone hcl buspirone hydrochloride busulfan clearance butenafine hcl cream butorphanol qid butyrophenone classes c-cholesterol ester fractional clearance rate c-cholesteryl oleate cadmium-zinc mixtures caffeine doses caffeine elimination caffeine theobromine grepafloxacin caffeine-containing products caffeine-related adverse effects calcium absorption calcium acetate calcium blockers calcium channel calcium channel antagonists calcium channel blocker calcium channel blocker diltiazem calcium channel blockers concentration caution calcium channel blockers diltiazem calcium channel-blockers calcium channel-blocking drugs calcium channels calcium concentrations calcium disodium calcium excretion calcium ions calcium levels calcium measurements calcium supplements-antacids products calcium-containing medicines calcium-dependent reactions calcium-entry antagonists calcium-entry blockers calcium-rich foods calculated digoxin calculated theophylline clearance calculus formation calmodulin kinase camp-mediated acid secretion camp-stimulated acid secretion can lead cancer cell growth cancer cells cancer centre cancer increases cancer metastasis cancer patients cancer recurrence cancer res candesartan cilexetil candida albicans canine experiments capsule formulation capsule formulation of cefprozil capsules garlic captopril tablets captopril therapy captopril's effect captopril-digoxin interaction carbachol-stimulated intracellular ca carbamate insecticides carbamazepine administration carbamazepine concentration carbamazepine concomitant administration carbamazepine concomitant administration of diltiazem carbamazepine epoxide carbamazepine epoxide plasma concentration carbamazepine epoxide steady-state cmin concentrations carbamazepine levels carbamazepine overdose carbamazepine plasma concentrations carbamazepine potential carbamazepine steady-state cmin carbamazepine therapy carbamazepine toxicity carbenicillin indanyl sodium carbidopa-levodopa combination products carbohydrate metabolism carbohydrate-splitting enzymes carbonic anhydrase inhibitor carbonic anhydrase inhibitors carcinogenesis pegasys carcinogenesis study carcinogenic potential carcinogenicity study cardiac abnormalities cardiac arrests cardiac arrhythmia cardiac arrythmias cardiac autonomic irritability cardiac capacity cardiac conduction cardiac conduction abnormalities cardiac contractility cardiac deaths cardiac disease cardiac dysfunction cardiac effects cardiac enlargement cardiac function cardiac monitoring cardiac myocyte membranes cardiac nitrates cardiac patients cardiac preparations cardiac stimulants cardiac transplant patients cardiac transplant recipients cardioactive compounds cardioactive drugs cardioplegic solutions cardiopulmonary arrest cardiopulmonary stimulation cardiorespiratory depression cardioselective beta-blocker cardioselective beta-blockers cardiovascular action cardiovascular adverse effects cardiovascular adverse events cardiovascular agents cardiovascular collapse cardiovascular depression cardiovascular drugs cardiovascular dysmetabolic syndrome cardiovascular effects cardiovascular morbidity cardiovascular patients cardiovascular prophylaxis cardiovascular risk cardiovascular safety cardiovascular status cardiovascular system care centre care units carinii pneumonia carotid cannulation carrier density carvedilol therapy carvedilol treatment cascade impactor case reports of patients case summary cases of conduction disturbance cases of diabetes cases of hyperpyrexia cases of propoxyphene overdosage cases of rhabdomyolysis cases of seizures caspofungin acetate caspofungin concentrations caspofungin disposition caspofungin trough concentrations castor oil catabloism of vitamin catabolism of vitamin catabolism of warfarin catecholamine depletors catecholamine levels catecholamine sensitivity catecholamine-depleting agents catecholamine-depleting drugs categories result cation transport cation-containing products cationic secretion cationic transport system cationic transporter systems causal dysregulation causal mechanism causative factors cause additive cns depression cause qt prolongation cause-and-effect relationship causing renin release causing renin release captopril's effect cbz epoxide phenobarbital ccnu cytotoxicity ccnu pharmacokinetics cecectomized rats cefamandole naftate cefdinir absorption cefdinir pharmacokinetics cefdinir plasma levels cefditoren pivoxil cefotaxime sodium ceftibuten auc ceftibuten cmax ceftibuten concentrations celecoxib metabolism celecoxib plasma concentration cell accumulation cell activation cell body cell counts cell culture cell cultures cell disease cell functions cell growth cell infiltration cell lines cell membrane cell membranes cell mitogen cell mutation assay cell number cell permeability cell resistance cell tumors cell type cell type-specific differences cell-free system cell-independent activator cellular aging cellular basis cellular permeability cellular sensitivity cellular uptake central action central anticholinergic syndrome central effects central importance central nervous function central nervous system depressant central nervous system depressant effects central nervous system depression central nervous system penetration central nervous system stimulants central obesity central opioid analgesia central pathways central stimulant effects central venous pressure centre inventory centroblast proliferation cephalosporin blood levels cephalothin sodium cercarial encystment cerebellar damage cerebral memory systems cerebroactive drugs cerebyx administration cerebyx dosage cerivastatin auc cerivastatin plasma concentrations cerivastatin sodium certain endocrine certain hmg-coa reductase inhibitors cervical dilatation cervical laceration cervical mucus cervical vertebra cessation of heparin therapy cessation of treatment cetirizine administration chance of side effects channel antagonists channel blocker channel blocker diltiazem channel blockers concentration caution channel blockers diltiazem channel blockers nimodipine channel subtypes channel-blocking drugs charcoal administration check serum potassium levels checkerboard assay chelated extracellular ca chelation complexes chelator therapies chemical agents chemical carcinogen chemical color development chemical reaction chemical resemblance chemical waste incineration chemically similar drug chemosensitizer misonidazole chemotherapeutic agents chemotherapy agents chemotherapy cycle chemotherapy dose chemotherapy regimens chemotherapy-induced mucositis chewable-dispersible buffered tablets chewable-dispersible tablet formulation chick embryos childbearing age childbearing potential chinese hamster chinese hamster's alpha chinese hamsters chloral hydrate chloride excretion chloride-induced gastrointestinal lesions asa result chlorpromazine blocks dopamine chlorpropamides plasma half-life chlorthalidone administration cholecystokinin octapeptide cholesterol concentration cholesterol levels cholesterol plasma levels cholesterol subfraction concentrations cholesterol synthesis cholestographic agents cholestyramine binds cholestyramine binds bile acids cholestyramine increases enterohepatic elimination cholestyramine resin cholestyramine-concomitant intake choline salicylate cholinergic blockade cholinergic crisis cholinergic functions cholinergic reactions cholinergic role cholinergic stimulation cholinesterase activity cholinesterase inhibitors chop chemotherapy chop patients chop-haart group chop-haart patients chop-like regimen choroidal blood flow chosen method chromaffin cell chromaffin cells chromatographic assay chromatographic-mass spectrometer technique chromatography procedure chromosomal aberration assay chronic activation chronic administration chronic alcohol abuse chronic alcoholism chronic canine experiments chronic co-administration chronic concomitant therapy chronic concurrent administration chronic dosing chronic dosing effects chronic experiments chronic flecainide therapy chronic high dose aspirin chronic indications chronic obstructive pulmonary disease chronic phenobarbital treatment chronic phenytoin chronic phenytoin therapy chronic renal dialysis chronic renal disease chronic renal failure chronic renal insufficiency chronic theophylline therapy chronic toxicity study chronic treatment chronic treatments chronic vascular rejection chronic warfarin therapy chronic warfarin treatment chronically implanted albino rats chronotropic effects chylomicron intravascular catabolism chylomicron lipolysis chylomicron metabolism chylomicron-like emulsion chylomicron-like emulsion model chylomicron-like emulsions ci contraindications cigarette smokers cime-tidine therapy cimetidine administration cimetidine careful monitoring cimetidine co-administration cimetidine co-administration of felodipine cimetidine coadministration cimetidine increases cimetidine therapy cimetidine treatment cinacalcet exposure cinese hamsters ciprofloxacin therapy circulating levels circulating metabolite circulatory depression cisapride absorption cisapride cause qt prolongation cisapride drugs cisapride increases cisapride interactions terfenadine cisapride levels cisapride metabolism cisapride opiate agonists fentanyl examples cisapride pharmacokinetics cisapride plasma concentrations cisapride therapy cisplatin dose cisplatin pharmacokinetics cisplatin therapy citalopram auc citalopram plasma levels citrate accumulation citrate elevations citrate tablets usp clarithromycin active metabolite clarithromycin clarithromycin concentration indinavir clarithromycin concentration indinavir class antimicrobial class drugs class examples class ia class iv myocardium classes of drugs clearance measurements clearance mechanism clearance mechanisms clearance of adrenocorticoids clearance of alosetron clearance of alprazolam clearance of amprenavir clearance of anagrelide clearance of benzodiazepines clearance of busulfan clearance of caffeine clearance of cetirizine clearance of corticosteroids clearance of diazepam clearance of digoxin clearance of drugs clearance of efavirenz clearance of ertapenem clearance of escitalopram clearance of fludrocortisone acetate clearance of gabapentin clearance of hydrodolasetron clearance of indinavir clearance of isradipine clearance of ketorolac clearance of lithium clearance of methotrexate clearance of morphine clearance of rifabutin clearance of salicylates clearance of theophylline clearance of tolbutamide clearance of triazolam clearance of ucb clearance of zalcitabine clearance rate clearance value clearance values clearances of dofetilide cleavable complex formation clindamycin-sensitive isolates clinical activity clinical acumen clinical aspects clinical basis clinical bleeding clinical comment antiarrhythmics clinical comment clarithromycin clinical comments clinical concern clinical conditions clinical consequences clinical data clinical differences clinical dose clinical drug interaction clinical drug interaction study clinical drug-drug interaction clinical effect clinical effect examples clinical effects clinical evaluation clinical experience clinical experiences clinical failures clinical implications clinical importance clinical interaction clinical interaction study clinical interest clinical isolates clinical judgement clinical laboratory clinical laboratory test clinical monitoring clinical patterns clinical pharmacokinetic clinical pharmacology drug interactions clinical pharmacology section clinical pharmacology study clinical pharmacology-pharmacokinetics-drug-drug interactions clinical presentation clinical problems clinical range clinical research centre clinical response clinical setting clinical significance unknown clinical signs clinical situation clinical status clinical studies asa result clinical studies involving alprazolam clinical studies propofol clinical study clinical toxicity clinical trial data clinical trials database clinical vancomycin-resistant strains clinically effective duration clinically important adverse interactions clinically important alterations clinically important effect clinically important effects clinically important interaction clinically important interactions clinically important pharmacokinetic interactions clinically important potentiation clinically meaningful clinically meaningful increases clinically meaningful interactions clinically meaningful reductions clinically normal dogs clinically relevant alterations clinically relevant concentrations clinically relevant consequences clinically relevant drug-drug interactions clinically relevant effect clinically relevant effects clinically relevant elevation clinically relevant exposures clinically relevant interaction clinically relevant interactions clinically relevant laboratory test abnormalities clinically relevant pharmacokinetic clinically relevant pharmacokinetic interactions clinically significant adverse interactions clinically significant adverse reactions clinically significant degree clinically significant differences clinically significant drug clinically significant drug inhibition clinically significant drug interactions clinically significant drug-drug interactions clinically significant effect clinically significant effects clinically significant hyperprolactinaemia clinically significant increases clinically significant interaction clinically significant interactions clinically significant pharmacokinetic clinically significant pharmacokinetic interaction clinically significant sequelae clinically significant symptoms clinitest reagent tablets clofibric acid clomiphenecitrate tablets usp clomipramine hcl clonazepam levels clonazepam metabolism clonazepam pharmacokinetics clonidine administration clonidine hydrochloride clonidine therapy clonidine withdrawl clorazepate dipotassium close clinical close collaboration close medical supervision clostridium difficile toxin clotting factor clotting factor synthesis clotting factors clotting time clozapine dose clozapine n-oxide clozapine plasma levels cmax auc cmax digoxin cmax levels cmax of acamprosate cmax of rofecoxib cmax values cmin concentration cmin concentrations cmv disease cns acting drugs cns agents cns depressant drugs cns depressant effect cns depressant effects cns depression producing medications cns depressive effects cns drugs cns effect cns effects cns effects of caffeine cns excitability cns lesions cns pharmacodynamic interaction cns stimulants cns toxicity brain hemorrhage cns vascular lesions cns-active drugs cns-active drugs ethanol cns-depressant action cns-depressant drug cns-depressant effects cns-depressive effect cns-depressive effects cns-impairing effects cns-related adverse effects co-administered antiepilepsy drugs co-administered avonex co-administered dose co-administered drug co-administered everolimus dose level co-administration of aliskiren co-administration of anastrozole co-administration of antacid co-administration of atorvastatin co-administration of beta-agonists co-administration of bosentan co-administration of bupropion co-administration of celecoxib co-administration of cephalexin co-administration of clozapine co-administration of corticosteroids co-administration of digoxin co-administration of enalapril co-administration of erythromycin co-administration of irbesartan co-administration of itraconazole co-administration of ketoconazole co-administration of linezolid co-administration of lisinopril co-administration of nelfinavir co-administration of nevirapine co-administration of phenobarbital co-administration of phenytoin co-administration of probenecid co-administration of tacrolimus co-administration of warfarin co-administration oft coadministered antiepileptic drugs coadministered antiretroviral agents coadministered concentration coadministered drug coadministered drugs coadministered levodopa-dopa-decarboxylase inhibitor coadministered medicinal products coadministering medications coadministration of almotriptan coadministration of alosetron coadministration of amprenavir coadministration of aprepitant coadministration of aspirin coadministration of astemizole coadministration of atorvastatin coadministration of baraclude coadministration of calcium channel blockers coadministration of carbamazepine coadministration of cimetidine coadministration of cisapride coadministration of cytochrome p coadministration of digoxin coadministration of diltiazem coadministration of drugs coadministration of efavirenz coadministration of entecavir coadministration of erythromycin coadministration of escitalopram coadministration of esomeprazole coadministration of eszopiclone coadministration of ethoxzolamide coadministration of felbamate coadministration of fluoxetine coadministration of fosinopril coadministration of gabapentin coadministration of glyburide coadministration of grapefruit juice coadministration of indinavir coadministration of indomethacin coadministration of ketoconazole coadministration of loratadine coadministration of loratadine relative coadministration of moclobemide coadministration of naratriptan coadministration of nifedipine coadministration of phenylbutazone coadministration of phenytoin coadministration of propoxyphene coadministration of propranolol coadministration of radiation therapy coadministration of ranitidine coadministration of rifampin coadministration of ritonavir coadministration of saquinavir coadministration of sirolimus coadministration of terfenadine coadministration of thioridazine coadministration of valdecoxib coadministration of viracept coadministration of warfarin coagulant activity coagulation alterations coagulation assays coagulation factor concentrates coagulation factors coagulation indices coagulation ketoprofen coagulation parameters coagulation system coagulation test coagulation tests coagulation time coagulation times coat-a-count ria kit coat-core formulation coated aspirin cobalt concentration cobalt excretion cobalt treatments cocaine abuse cocaine abusers cocaine dependence cocaine dose cocaine drug hunger cocaine exposure cocaine hunger cocaine-induced behavioral sensitization cocaine-induced increases cocaine-treated animals cocaine-treated groups cocaine-treated sst codeine combinations cognitive dysfunction cognitive enhancing effects cognitive function cohort data cohort design coingestion of acetaminophen colchicine para-aminosalicylic acid colestid tablets colestipol hydrochloride colestipol resins colestipol-concomitant intake colestld tablets coli endotoxin collagen-induced platelet aggregation collagen-stimulated platelet aggregation collapse-respiratory arrest-cardiac arrest colonic fluid colonic fluid contents colonic transit-enhancing effect color development colorectal cancer colostrum iga combination arenot combination chemotherapy regimens combination drug treatment combination hormonal contraceptives combination lies combination of amiodarone combination of anakinra combination of drugs combination of furosemide combination of galangin combination of ketoprofen combination of methotrexate combination of probenecid combination of rifampicin combination of therapy combination oral contraceptives combination procedures combination products combination regimens combination study combination therapies combinational action combinations of arginine combinations of clindamycin combinations of clozapine combined administration combined chemotherapy combined data combined drug actions combined effects combined exposure combined exposures combined hormonal contraceptives combined hyperglycaemia combined moieties combined oral contraceptives combined therapy combined transcriptional activator combined treatment combining digoxin comment antiarrhythmics comment clarithromycin commercially available assay methods toxi-lab committed step common adverse effects common adverse reaction common adverse reactions common comorbidity common component common findings common medications common pathogens common phenotypic subset common transport pathway commonside effects comparable activity comparable cognitive enhancing effects comparative data comparative slaughter technique comparative study comparison of digitalis tolerance comparison study compatibility data compelling reasons compensatory increase compensatory increases compensatory tachycardia competing drug competitive displacement competitive inhibition competitive inhibitor competitive interaction competitive renal excretory sites competitive suppression complete heartblock complete loss complete mental alertness complete prescribing information complex anions complex concentrates complex effect complex fashion complex formation complex of treatment measures complex renal therapy regimens complication of ketoprofen treatment complication of warfarin treatment complications of retinopathy component of insect comprehensive information comprehensive review compromised cardiovascular system compromised norepinephrine compromised renal function concentration caution concentration clinical significance concentration coadministration concentration combination concentration curve concentration data concentration dose reduction concentration increases concentration index concentration indinavir concentration monitoring concentration of budesonide concentration of d-amphetamine concentration of digitalis preparations concentration of duloxetine concentration of norepinephrine concentration plasma concentrations concentration profile concentration ranges concentration ratios concentration rifabutin concentration ritonavir concentration saquinavir concentration time-curve concentration use lowest possible dose concentration-dependent relaxation concentration-response curves concentration-response manner concentration-responses curves concentrations cyp concentrations drugs concentrations fo concentrations of alcohol concentrations of cefotetan concentrations of cefoxitin concentrations of cilostazol concentrations of clindamycin concentrations of dexamethasone concentrations of digoxin concentrations of drugs concentrations of duloxetine concentrations of furosemide concentrations of lapatinib concentrations of losartan concentrations of norepinephrine concentrations of phenytoin concentrations of salicylate concentrations of serum concentrations only zinc concomitan administration concomitant agent concomitant alcohol concomitant allopurinol concomitant amprenavir concomitant anesthetic concomitant antihypertensive agents concomitant antihypertensive medications concomitant aspirin concomitant atorvastatin administration concomitant augmentin xr concomitant bepridil hydrochloride concomitant bezafibrate concomitant carbamazepine administration concomitant cetirizine administration concomitant chemotherapy concomitant ciprofloxacin concomitant ciprofloxacin therapy concomitant cyclophosphamide concomitant diuretics concomitant drug administration concomitant drug clinical comment clarithromycin concomitant drug cmaxss concomitant drug therapy concomitant drugs concomitant erythromycin therapy concomitant gabapentin concomitant gabapentin administration concomitant high-dose aspirin concomitant indinavir therapy concomitant intake concomitant interferon concomitant intravenous misuse concomitant irbesartan concomitant lenalidomide administration concomitant lithium concomitant lovastatin concomitant medication concomitant methotrexate concomitant mtx concomitant oral administration concomitant oral medication concomitant phenytoin administration concomitant protease inhibitor therapy concomitant quinolone concomitant serotonergic agents concomitant single dose administration concomitant strong inducers concomitant strong inhibitors concomitant substrate drug concomitant supplementation concomitant theophylline concomitant theophylline therapy concomitant theophylline-quinolone therapy concomitant therapies concomitant useof rifampicin concomitant warfarin concomitant warfarin administration concomitant warfarin therapy concomitantly administered aspirin concomitantly administered diltiazem concomitantly administered drugs concomitantly given lithium concomitantly given thiazide diuretics concomitantly used anticholinergic medications concurent therapy concurrent cimetidine therapy concurrent dosing concurrent enbrel concurrent high-dose aspirin therapy concurrent hypnotic medications concurrent ingestion concurrent irinotecan concurrent kineret concurrent levamisole concurrent medications concurrent treatment concurrent usage concurrently administered antiepileptic drugs conditioning processes conditions of patients conduction abnormalities conduction disturbance conduction time confidence limit confirmation test confirmed interactions conflicting reports confusional states congestive heart failure post-myocardial infarction conjugated dienes conjugated estrogens conjugated system conjunction with tricor conscious sheep consecutive oral contraceptive cycles consensus reports consequent possible decrease conservative approach considerable caution considerable effect considerable evidence considerable segment considerable variability consistent effects constant values constellation of symptoms constructive alternatives consumption of alcohol continued admistration continuing rise continuing surveillance contortrostatin treatment contortrostatin-induced phosphorylation contraception inwomen contraceptive agents ethinylestradiol contraceptive cycles contraceptive effect contraceptive effectiveness contraceptive efficacy contraceptive measures contraceptive norethindrone-ethinyl estradiol contraceptive ortho-novum contraceptive product contraceptive regimen contraceptive users contraceptives co-administration contraceptives differin their effectiveness contraceptives ethinylestradiol contraceptives keppra contraceptives multiple doses contraceptives rofecoxib contractile response contractile responses contraction of guinea-pig vas deferens contrast media contrast reactions contributing factor contribution of adenosine receptors control group control levels control mechanisms control mechanisms of magnesium status control of blood glucose control period control pills control products control program control rats control values controlled clinical pharmacology controlled clinical study controlled clinical trial controlled clinical trials controlled crossover controlled hypotensive anesthesia controlled study controlled-release morphine capsule conventional antipsychotics conventional formulation converting enzyme converting enzyme inhibitors coombs reactions coombs test coombs testing coombs tests coordination disorder copd medications copd patients copd symptoms copegus pregnancy registry copegus therapy copegus treatment copper reduction tests copper sulfate tests copper-reduction method copying test cord injuries cordarone administration core temperature coreg slow av conduction corn oil corneal lesions coronary artery vasospasm coronary insufficiency coronary vasodilators corrected qt interval corrected qt intervals corrective measures correlative clinical cortical tissues corticosteroid binding globulin corticosteroid clearance corticosteroid dosage corticosteroid dose corticosteroid levels corticosteroid side effects corticosteroid synthesis corticosteroid therapy corticosteroid withdrawal corticosteroid-binding globulin cortisol concentration cortisol levels cortisone-like medicine cost-risk-benefit balance coumarin anticoagulants altered coagulation parameters coumarin drugs coumarin metabolism coumarin therapy coumarin type coumarin-derivative anticoagulants coumarin-like drugs courses of therapy covers pharmacology creatine phosphokinase creatine positive antinuclear phosphokinase antibody creatinine clearance creatinine concentration creatinine level creatinine levels creatinine values cremophor el crescentic iga glomerulonephritis critical fall crixivan drug class crohns disease cromolyn sodium cross-over study cross-reactivity of carbamazepine cross-sectional descriptive study crossover design crude tannic acid crushed subutex tablets cryptosporidium parvum cryptosporidium parvum growth crystalline zinc insulin preparations cumulative doses cumulative incidence cumulative urinary excretion curare-like compounds curariform effect curariform muscle relaxants cure of melarsoprol cure rates curve of albendazole sulfoxide curve of diltiazem cushingoid appearance cutaneous infectious disease cyclase activity cyclase desensitization cycle duration cycle irregularities cyclic amp pde cyclic antidepressants cyclophosphamide treatment cyclosporin level cyclosporine concentrations cyclosporine dosage cyclosporine dosage adjustments cyclosporine dose cyclosporine doses cyclosporine large quantities cyclosporine levels cyclosporine serum levels cyclosporine trough concentrations cyclosporine-induced toxicity cynomolgus monkeys cyp enzyme cyp isoenzymes cyp isoforms cyp metabolism cyp-mediated drug clearance cypermethrin administration cypermethrin exposure cypermethrin exposure of rats cypermethrin-induced oxidative stress cyst patients cyst-exposed parasites cysteine conjugation cysteine moieties cystic fibrosis therapies cystic fluid cytochrome isozymes cytogenetics study cytoplasmic condensation cytoprotective properties cytosine arabinoside cytostatic agent cytotoxic actions cytotoxic activity cytotoxic agents cytotoxic chemotherapy cytotoxic drugs cytotoxic effect d-gal binding lectin daily brovana dose dantrium metabolism dantrolene sodium dapsone hydroxylamine dapsone treatment dasatinib exposure dasatinib plasma concentrations dasatinib plasma concentrations cyp date levosimendan day decreases indomethacin blood levels day etofibrate day of therapy day of vistide infusion day pretreatment period day-to-day variability days fulvestrant days of co-administration days of dofetilide treatment de pointe de pointes de pointes-type ventricular tachycardia dea concentrations decarboxylase inhibitor decins sans fronti res decongestant drugs decrease excretion decrease excretion of amphetamines decrease extracellular levels decrease gefitinib metabolism decrease imatinib plasma concentrations decrease ineffectiveness decrease mean cmax digoxin decrease of nucleolin-c decrease of nucleophosmin-b decreased alertness decreased antihypertensive effect decreased antiretroviral effect decreased blood levels decreased cardioselectivity decreased clearance decreased concentrations decreased contraceptive effectiveness decreased effectiveness decreased efficacy decreased free thyroxine decreased hdl decreased indinavir concentrations decreased levels decreased metabolism decreased nelfinavir plasma concentrations decreased plasma concentration decreased plasma concentrations decreased plasma level decreased plasma levels decreased pregnanediol excretion decreased psychomotor decreased renal excretion decreased renal function decreased response decreased salicylate serum levels decreased saquinavir plasma concentrations decreased serum levels decreased synthesis decreased urinary levels decreases hydrocodone decreases indomethacin blood levels decreases of norethindrone decreasing heparin effect deep-seated infection deet toxicity defecation episodes deferasirox metabolism defined physical dependency definite nondepolarizing degree of accumulation degree of anticoagulation degree of apoptosis degree of enhancement degree of heart failure degree of heartblock degree of hypotension degree of protein binding degree of stereoselectivity degree of variability degrees of heartblock degrees of inhibition degrees of recovery dehydrated alcohol usp dehydrogenase inhibition dehydrogenase pyrroloquinolinequinone delavirdine indinavir concentration dose reduction delavirdine-based regimens delayed elimination delayed respiratory depression delayed-release capsules deleterious effect deleterious effects deleterious interactions demographic groups demonstrated efficacy denileukin diftitox denovo kidney allograft recipients denovo renal transplant recipients dental complications deoxycytidine kinase dependent diabetic patients dependent hypertension dependent manner dependent measures depletion of pertechnetate depressant drugs depressant effect depressant effects depressant effects of antihistamines depressants such as narcotics depression producing medications depressive effects depressive symptomatology depressive symptoms depth of involvement derivative implications derivatives antimycobacterial agents derivatives voriconazole established drug interactions desbutyl levobupivacaine descarboethoxyloratadine erythromycin descending pain descriptive study designing experiments desipramine hydrochloride desirable antimuscarinic effects desired anticoagulant effect desired diuretic desired effect desired hypotensive response desired lactulose-induced drop desired response desired therapeutic effect desmopressin tablets detailed pharmacokinetic evaluation detectable effect detectable limits detection of exposure deterioration of asthma control determinant gene transfer determinant of bioavailability determinant of sensitivity determinants of drug sensitivity determination of antibacterial drug levels determination of creatinine values determination of prothrombin time determinations of serum digoxin levels determined on different days determined that the prothrombin time-inr determining levels detoxification of azathioprine detrimental effects developing methemoglobinemia developing monkeys developing peripheral neuropathy developing renal failure developing rhabdomyolysis development of brain edema development of dependence development of hypokalemia development of myalgia development of thrombosis development of withdrawal symptoms developmental acquisition dexamethasone co-administration dexamethasone doses dexamethasone suppression test dexrazoxane administration dextromethorphan hydrobromide dextromethorphan plasma levels dextrorotatory isomer diabetes medicine diabetic chinese hamster diabetic chinese hamster's alpha diabetic chinese hamsters diabetic cinese hamsters diabetic drugs diabetic individuals diabetic ketoacidosis diabetic patient diabetic patients response diabetic rats diagnosed subjects diagnosis of magnesium deficiency diagnostic blood assays diagnostic challenge diagnostic dip-stick methodology diagnostic interference diagnostic methods diagnostic serum tests diagnostic tests dialysis solutions dialyzable drugs diamond patient populations diamond trials diarrhea model diarrhea-inducing effects diazepam administration diazepam plasma exposure diazoxide infection dibutyryl camp diclofenac dose diclofenac therapy dicumarol therapy didanosine administration didanosine administration indinavir didanosine co-administration didanosine formulations didanosine indinavir didanosine pharmacokinetics didanosine-placebo tablets dideoxyinosine pharmacokinetics dietary cobalt concentration dietary cobalt treatments dietary concentrations dietary deficiencies dietary iodine dietary phenobarbital dietary salt restriction dietary treatments dietary-induced obese rats dietary-obese rats different ca different days differential actions differential diagnosis differential effect differential effects differential regulation differential scanning calorimetry differential sensitivity differential thermal analysis differin gel differin their effectiveness difficile toxin diffuse muscle pain diffusible anti-helminthic treatment diflunisal levels diflunisal tablets digestive enzyme preparations digit symbol substitution test digital extensor tension digitalis administration digitalis administration of diltiazem hydrochloride digitalis dosage digitalis glycosides enhanced possibility digitalis intoxication digitalis levels digitalis therapy digitalis tolerance digitalis toxicity digitalis treatment digitalized patient digitalized patients digitoxin administration digitoxin concentrations digoxin absorption digoxin auc digoxin bioavailabillty digoxin blood levels digoxin clearance digoxin cmax digoxin concentration digoxin concentrations digoxin dose digoxin dose adjustment digoxin doses digoxin elixir digoxin half-life digoxin half-life of elimination digoxin increases digoxin keppra digoxin level digoxin median tmax digoxin pharmacokinetics digoxin plasma concentrations digoxin protein binding digoxin serum levels digoxin therapy digoxin toxicity digoxin treatments digoxin volume digoxin volume of distribution digoxin-amiodarone interaction dihydroergotamine acute ergot toxicity dihydroergotamine mesylate dihydropyridine calcium antagonists dihydropyridine calcium channel blockers dihydropyridine derivative diltiazem auc diltiazem coadministration diltiazem dose diltiazem hydrochloride diltiazem hydrochloride therapy diltiazem plasma concentrations diltiazem plasma levels diltiazem therapy diltiazem type dilution method diminished binding diminished effect diminished effects diminished efficacy diminished prothrombin response diminished renal function diminished response dip-stick methodology diphenhydramine hydrochloride diphenoxylate hcl diphenoxylate hydrochloride diplococcus pneumoniae dipstick test dipyridamole usp direct action direct cardiac stimulants direct causal relationship direct coombs reactions direct coombs test direct coombs tests direct effects direct glucuronidation direct pharmacokinetic captopril-digoxin interaction direct treatment costs dirithromycin tablets discontinuation of amiodarone discontinuation of cisapride therapy discontinuation of dexfenfluramine discontinuation of leflunomide discontinuation of lithium discontinuation of rifampicin discontinuation of rifampin discontinued therapy discontinuing therapy discrete responses discrimination task disease medications disease symptoms disintegrating tablet disintegrin contortrostatin disintegrin family disintegrins echistatin disoproxil fumarate disopyramide levels disopyramide phosphate disopyramide plasma levels displacement of fenoprofen displacement of radiopertechnetate displacing effect disposition of compounds disposition of eszopiclone disposition of phenytoin disposition of theophylline disposition of zaleplon disruptive effects dissolution experiments dissolution of aerosol particles dissolution rate dissolution rate of aerosol particles distinctive effects distribution of cloxacillin distribution of phosphatases distribution of theophylline concentrations distribution pathways disturbances of blood glucose disturbances patients disulfiram therapy disulfiram-ethanol reaction disulfiram-like reaction diuretic absorption diuretic activity diuretic agents diuretic efficacy diuretic response diuretics area major contributing factor diuretics lotensin divalproex sodium diverse potassium channel divided attention test divided doses dna damage dna-damaging agents documented hypokalemia dodecyl sulfate dofetilide auc dofetilide cmax dofetilide exposure dofetilide levels dofetilide peak plasma levels dofetilide plasma levels dofetilide treatment dogwhelk nucella lapillus dolasetron mesylate domain decoy donor compounds dopamine agonist dopamine agonists dopamine antagonists dopamine concentrations dopamine hcl dopamine infusion dopamine receptor dopamine receptors dopamine release dopamine-induced renal dopamine-induced ventricular arrhythmias dopaminergic agents dopaminergic renal dorsocervical fat enlargement dosage adjustment of antigout medications dosage adjustment of quetiapine dosage adjustment of zaleplon dosage adjustments of theophylline dosage adjustments of valproate dosage forms dosage forms of digoxin dosage levels dosage modifications dosage of digoxin dosage of flecainide dosage of heparin dosage of imipramine dosage of ouabain dosage of phenytoin dosage of phosphate-binding agents dosage of theophylline dosage of vitamin k antagonists dosage of warfarin dosage range dosage reduction dosage replacement dosage schedule dosages of fluoxetine dose adjustment of azithromycin dose adjustment of bosentan dose adjustment of digoxin dose adjustment of lapatinib dose adjustment of metformin dose adjustments dose administration dose administration of tiagabine dose administration of valdecoxib dose aspirin dose bioavailability dose decrease dose dependent manner dose dopamine infusion dose fractions dose group dose groups dose heparin dose increase dose increase of lopinavir-ritonavir dose increases dose level dose levels dose modification dose of adrenaline dose of albendazole dose of allopurinol dose of aripiprazole dose of atazanavir dose of atorvastatin dose of azithromycin dose of beta-agonist bronchodilator drugs dose of bupropion dose of butorphanol dose of carcinogen dose of ciprofloxacin dose of cisplatin dose of corticosteroid dose of cyclosporine dose of dexamethasone dose of didanosine-placebo tablets dose of digoxin dose of digoxin elixir dose of diltiazem dose of endotoxin dose of ethanol dose of indinavir dose of levorphanol dose of levothyroxine sodium dose of lomefloxacin dose of mercaptopurine dose of midazolam dose of naloxone dose of phenytoin dose of picrotoxin dose of pimozide dose of pravastatin dose of propranolol dose of rifabutin dose of ritonavir dose of sirolimus dose of succinylcholine dose of sumatriptan dose of theophylline dose of thiosulfate dose of tolbutamide dose of warfarin dose of warfarin sodium dose of zalcitabine dose of zaleplon dose pharmacokinetics dose proleukin dose range dose ranges dose reduction of azathioprine dose reductions dose relationship dose requirement dose requirement of digoxin dose selection dose study dose warfarin dose-dependent increase dose-dependent inhibition dose-dependent modification dose-limiting organ dose-limiting toxicities dose-related blockade dose-related decrease dose-related increase dose-response curves dose-response models dose-time effects doses of adenosine doses of alefacept doses of aminoglycosides doses of antacid doses of antacids doses of aprepitant doses of atorvastatin doses of bupropion doses of caffeine doses of cefditoren pivoxil doses of cimetidine doses of cisplatin doses of diflunisal doses of digoxin doses of diltiazem doses of dopamine doses of endotoxin doses of ergotamine-containing drugs doses of erythromycin doses of estradiol doses of estrogen doses of ethchlorvynol doses of fulvestrant doses of heparin doses of ketoconazole doses of leucovorin doses of lovastatin doses of magnesium doses of naloxone doses of omeprazole doses of paroxetine doses of phenobarbital doses of quinolones doses of rifampin doses of salicylates doses of sildenafil doses of sodium perchlorate doses of theophylline doses of valdecoxib doses of vitamin doses of warfarin doses of zaleplon dosing adjustments dosing effects dosing interval dosing lapatinib dosing regimens dosing requirements dosing schedule double-blind comparative study double-blind fashion double-blind study doubling times doubt complex down-regulation of nucleophosmin-b downward adjustment downward dose adjustment doxazosin auc doxazosin binding doxazosin mesylate doxazosin mesylate tablets doxorubicin hcl dpcpx-induced anxiogenic effects dramatic effect drinking alcohol drl schedule drowsiness-causing antihistamines drug absorption drug abuse drug actions drug addicts drug class drug class drugs drug class examples drug classes drug clearance drug clearance mechanism drug clinical comment clarithromycin drug cmaxss drug combination drug combinations drug concentration drug concentrations drug coverage drug discrimination drug disposition drug distribution pathways drug effect drug effect probenecid prolonged action drug effects drug elimination procedure drug events drug exposure drug extraction drug fenbufen drug fraction drug hunger drug indomethacin drug ingestion drug inhibition drug inhibition of cytochrome p drug inter-action drug interaction data drug interaction information digoxin drug interaction studies of ketoconazole drug interaction study drug interactions cimetidine drug interactions danazol drug interactions dofetilide drug interactions oral contraceptives keppra drug interactions several drug interaction drug interference drug laboratory test interactions drug level drug levels drug metabolism drug metabolizing enzymes drug monitoring drug name clinical comment antiarrhythmics drug name effect drug overdosage drug overdose drug products drug reaction drug reactions drug regimen drug regimens drug requirements drug rifampin drug sensitivity drug side effects drug status drug targets drug toxicity drug transport systems lapatinib drug-added drug combinations drug-drug interaction drug-drug interaction study drug-drug interactions drug-drug interactions albuterol drug-drug interactions cimetidine drug-drug pharmacokinetic drug-drug pharmacokinetic interactions drug-food interactions drug-induced cns-related adverse effects drug-induced renal toxicity drug-lab interactions drug-laboratory interactions drug-laboratory test interaction drug-laboratory test interaction captopril drug-laboratory test interaction fosinopril drug-laboratory test interactions acetaminophen drug-laboratory test interactions bisphosphonates drug-laboratory test interactions blood glucose drug-laboratory test interactions cephalosporins drug-laboratory test interactions corticosteroids drug-laboratory test interactions dactinomycin drug-laboratory test interactions effect drug-laboratory test interactions false elevations drug-laboratory test interactions finasteride drug-laboratory test interactions frova drug-laboratory test interactions increases drug-laboratory test interactions naproxen drug-laboratory test interactions phenytoin drug-laboratory test interferences drug-laboratory test-interactions drug-laboratory tests interactions drug-metabolizing enzyme system drug-metabolizing enzymes drug-specific interactions drugs aliskiren drugs antiarrhythmics amiodarone drugs aripiprazole drugs bacitracin drugs bioavailability drugs can lead drugs decreasing heparin effect drugs drug interactions drugs enhancing heparin effect drugs ethanol drugs given concurrently drugs highly drugs highly bound drugs lower bloodpressure drugs of abuse drugs phenytoin drugs whose absorption drugs whose efficacy drying effect dryness of mouth dsm-iv-diagnosed schizophrenia dsst scores dual-memory theories duloxetine absorption duloxetine clinical trials database duloxetine metabolism duloxetine-treated patients duodenal arsenate absorption duodenal loop technique duration of action duration of administration duration of block duration of sleep time duration of therapy durations of sleep durations of time dynamic insulin dyskinesia side reactions dysmetabolic syndrome e-strain subjects eagles minimal essential tissue culture early-phase schizophrenia ecg intervals ectopic pacemaker activity ectopic pregnancies edetate calcium disodium educational messages efavirenz appropriate doses efavirenz concentration clinical significance efavirenz concentration saquinavir efavirenz concentrations efavirenz efavirenz appropriate doses efavirenz indinavir concentration efavirenz plasma concentrations efavirenz plasma levels effect clinical comment clarithromycin effect examples effect of acitretin effect of adenosine effect of administration effect of aeds effect of alcohol effect of alosetron effect of amevive effect of amprenavir effect of anastrozole effect of anticoagulants effect of antihistamines effect of antihypertensive compounds effect of antihypertensive drugs effect of antihypertensives effect of aprepitant effect of aspirin effect of atropine effect of azithromycin effect of bishydroxy-coumarin effect of caffeine effect of carbachol effect of catecholamines effect of ceftibuten effect of celecoxib effect of cerivastatin sodium effect of cerulein effect of cimetidine effect of clidinium effect of clofarabine effect of clonazepam effect of cobalt effect of corticosteroids effect of coumarin effect of cyclosporin effect of cyclosporine effect of desflurane effect of diazepam effect of diethylpropion effect of diethylstilbestrol effect of digoxin effect of digoxin levels effect of disease states effect of dofetilide effect of dofetillide effect of dopamine effect of drugs effect of enkephalins effect of epinephrine effect of escitalopram effect of estradiol effect of etofibrate effect of famotidine effect of fluoxetine effect of food effect of foods effect of furosemide effect of gabapentin effect of ginsenosides effect of glibenclamide effect of glutamate effect of glycine effect of grepafloxacin effect of guanfacine effect of heparin effect of hydrochlorothiazide effect of induction effect of insulin effect of iron effect of loperamide effect of medroxyprogesterone acetate effect of meperidine effect of metamizol effect of methenamine effect of methotrexate effect of miconazole effect of morphine effect of norepinephrine effect of ouabain effect of oxytocin effect of penicillin effect of penicillins effect of phenobarbital effect of phenothiazines effect of probenecid effect of ras effect of rifampin effect of rofecoxib effect of sandimmune effect of sodium carboxymethylcellulose effect of sodium nitroprusside effect of steady-state effect of steroid effect of succinylcholine chloride effect of temperature effect of theophylline effect of tolbutamide effect of treatment effect of triazolam effect of tubocurarine effect of valdecoxib effect of valproate effect of vasodilators effect of veratrum alkaloids effect of vinorelbine effect of warfarin effect of zalcitabine effect ofe effect probenecid prolonged action effect profile effect relationship effect valdecoxib effective clozapine dose effective concentration effective contraception effective dose effective duration effective first-line therapy effective forms effective treatment effectiveness of combination effectiveness of norepinephrine effectiveness of olanzapine effectiveness of polyenes effectiveness of short-acting effector ieg arc effector iegs effector potentiation effects celecoxib effects of adenosine effects of adenosine receptor antagonists effects of alcohol effects of aliskiren effects of allopurinol effects of amphetamine effects of amphetamines effects of androgens effects of anticoagulants effects of antiglaucoma agents effects of antihistamines effects of antihistaminics effects of antihypertensive drugs effects of antihypertensives effects of apomorphine effects of aripiprazole effects of atropine-type drugs effects of benzodiazepines effects of beta-agonists effects of biocytin inclusion effects of bosentan effects of butalbital effects of butorphanol effects of caffeine effects of calcium blockers effects of catecholamines effects of chlordiazepoxide effects of chlorpromazine effects of cisapride effects of coadministration effects of contortrostatin effects of coumarin derivatives effects of d-amphetamine effects of desipramine effects of diethylpropion effects of diethylpyrocarbonate effects of digitalis effects of digitalis glycosides effects of diltiazem effects of dopamine effects of drug effects of drugs effects of epinephrine effects of escitalopram effects of ethanol effects of etofibrate effects of fexofenadine effects of filipin effects of fulvestrant effects of furosemide effects of gentamicin effects of glimepiride effects of glucocorticoids effects of glucose effects of grepafloxacin effects of guanethidine effects of hydralazine effects of insulin effects of isosorbide dinitrate effects of isosorbide mononitrate effects of ketamine effects of levodopa effects of loop diuretics effects of morphine effects of muscle relaxant drugs effects of nitrates effects of nitroglycerin effects of norepinephrine effects of olanzapine effects of oleate effects of phenytoin effects of piperazine effects of probenecid effects of psychostimulants effects of reseveratrol effects of resveratrol effects of ruthenium red effects of serotonin effects of sertonin effects of stimulants effects of stimulation effects of stress effects of sympathomimetics effects of theophylline effects of triazolam effects of uptake effects of warfarin effects of xanthine derivatives efficacious effects efficacy benefit efficacy data efficacy of amevive efficacy of amphetamines efficacy of anakinra efficacy of antipsychotics efficacy of ibutilide efficacy of lofexidine efficacy of sildenafil efficacy ofthe drug efficacy overuse efficient labeling efficient substrate efflux transporter p-glycoprotein egg weight eia test eight days eight experiments eight healthy volunteers eight hiv-infected individuals eight hiv-infected patients eight neurocysticercosis patients eight poisonings eight target drug-added drug combinations elderly patients elderly population electrically stimulated electrocardiographic abnormalities electrocardiographic qt-qtc interval prolongation electrocardiographic qtc interval electroconvulsive therapy electrolyte abnormalities electrolyte alterations electrolyte depletion electrolyte disturbances electrolyte disturbances patients electrolyte imbalance electrolyte loss electrophilic agents electrophilic chemicals electrophysiologic interactions elemental iron elevated blood cisapride levels elevated carbamazepine levels elevated cerebral elevated cpk levels elevated creatine phosphokinase elevated creatinine elevated cyclosporine serum levels elevated digoxin levels elevated digoxin serum levels elevated glucose levels elevated international normalized ratio elevated levels elevated liver aminotransferases elevated liver enzymes elevated liver function tests elevated plasma alprazolam concentrations elevated plasma concentrations elevated plasma levels elevated serum concentrations elevated serum levels elevated serum theophylline levels elevation of blood sugar elevation of bloodpressure elevation of plasma lithium elevation of plasma lithium levels elevation of serum potassium elevations of aminotransferase elevations of cholesterol elevations of digoxin concentrations elevations of liver enzymes elimination half-life of caffeine elimination half-life of sirolimus elimination halflife elimination halflife of midazolam elimination of amiodarone elimination of cloxacillin elimination of digoxin elimination of eszopiclone elimination of isoniazid elimination of lome-floxacin elimination of methotrexate elimination of sodium elimination of zalcitabine elimination of zaleplon elimination pathways elimination procedure elimination rate elimination route elimination route of fibrate drugs elspar therapy embryo-fetal development embryocidal effects embryonic survival emergency situation emerging roles emetic response empiric adjustment employed clinical laboratory tests empty stomach emulsion model enalapril iv attenuate potassium loss enantiomer of carvedilol enantiomer pharmacokinetics enbrel ci encephalopathic syndrome endemic primate gammaherpes virus endocrine drugs endocrine dysfunction endocrine feedback alterations endocrine function hmg-coa reductase inhibitors endocrine status endogenous insulin secretion endogenous marker endogenous oxytocin endogenous plasma levels endogenous prostaglandin synthesis endogenous respiration endogenous steroid hormones endorphinergic system endoscopic gastroduodenal ulcers endoscopy study endothelial denudation endothelial dysfunction endothelial function endothelium-intact aortic rings endotoxin-induced deaths endotoxin-treated rats enfuvirtide dose enhanced absorption enhanced bone marrow suppression enhanced drug effect enhanced effects enhanced hypokalemia enhanced learning enhanced possibility enhanced secretion enhanced sedative side effects enhanced theophylline clearance enhanced verografine enhancement effect enhancement of allopurinol toxicity enhancement of effects enhancement of growth enhancing effects enhancing heparin effect enkephalinergic neurons enoxacin administration enoxacin bioavailability enoxacin levels entacapone excretion enteric coated aspirin enteric coating enteric gram-negative bacilli enterococcus faecalis enterococcus faecium enterohepatic circulation enterohepatic elimination enterotoxic activities environmental lead enzymatic glucose oxidase enzymatic glucose oxidase reactions enzymatic oxidation enzymatic test enzymatic test strip usp enzymatic-based amylase assays enzyme abnormalities enzyme activities enzyme activity enzyme elevations enzyme function enzyme group enzyme inducer enzyme induction enzyme induction potential enzyme inhibitor enzyme inhibitors enzyme of zaleplon enzyme oxidation system enzyme preparations enzyme supplements enzyme-based tests enzyme-inducer phenytoin enzyme-inducing aeds enzyme-inducing drugs enzyme-inducing properties enzymes carbamazepine enzymes lapatinib epa dose epa supplements epidemic proportions epidermal necrolysis epidural clonidine epidural local anesthetics epidural morphine epilepsy patients epileptic pateint epileptic patients epileptic seizure epinephrine effect epiphyseal closure epirubicin metabolism epirubicin-based chemotherapy episode of migraine epithelial membrane epoxide concentrations epoxide hydrolase epoxide hydrolase carbamazepine epoxide hydrolase inhibitors epoxide metabolite epoxide phenobarbital epoxide plasma concentration epoxide reductase epoxide steady-state cmin concentrations eprosartan doses eprosartan pharmacokinetics equal concentrations equal groups equilibration of budesonide equilibrium solubilization equipotent inducers equivalent volume erectile dysfunction erection disorder erection disorders erection-supporting medication ergot alkaloid class ergot alkaloids ergot alkaloids ergotamine immunosuppressants cyclosporin ergot derivatives ergot derivatives antimycobacterial agents ergot therapy ergot toxicity ergot-containing drugs ergot-type oxytocic drugs ergotamine immunosuppressants cyclosporin ergotamine-containing drugs erlotinib auc erlotinib exposure error structures ertapenem concentrations erythrocyte acetylcholinesterase erythrocyte haemagglutination assay erythromycin breath test erythromycin co-administration erythromycin co-administration of felodipine erythromycin products erythromycin therapy escherichia coli escherichia coli endotoxin escitalopram clearance escitalopram metabolism esmolol hcl esomeprazole therapy esophageal motility dysfunction essential tissue culture established drug interactions estazolam concentrations ester fractional clearance rate estimates of steady-state estimates of theophylline clearance estimation of glucose tolerance estradiol concentrations estradiol ethinyl estradiol group estradiol groups estradiol norethindrone oral contraceptives estrogen activity estrogen concentrations estrogen therapy estrogen-containing compounds estrogen-containing therapies estrogen-dependent signalling estrogen-progesterone oral contraceptive estrogenic component estrogens fluoxetine etanercept therapy ethacrynic acid ethambutol administration ethanol administration ethanol cause additive cns depression ethanol challenge ethanol ingestion ethanol solution ethanol solutions ethanol's augmentation ethanol's augmentation of component p ethanol-drug reaction ethanolysis of temazepam ethanolysis reaction ethinylestradiol concentrations ethinylestradiol ethinyl ethinylestradiol levels ethinylestradiol norethindrone oral contraceptives ethinylestradiol-levonorgestrol oral contraceptive product ethosuximide levels etodolac capsules etodolac clearance etodolac pharmacokinetics etodolac-treated patients etofibrate treatment etomidate antagonism opioid analgesics etoposide exposure eulexin capsules euthyroid state evaluating men evaluation of prothrombin time evening meal event profile everolimus auc everolimus dose level everolimus dose-proportionality everolimus doses everolimus exposure everolimus exposure-response relationships everolimus steadystate everolimus tablets evidence of cytochrome p evidence of drug interactions evidence of glucose intolerance evidence of hypoglycemia evidence of incompatibility evidence of induction evidence of interaction evidence of interactions evidence of mutagenicity evidence of obstruction evidence of ovulation evidence of toxicity evoked potential components evoked potentials exacerbation of angina exacerbation of tachyarrhythmias exact length exact place exaggerated hypertensive responses exaggerated leukopenia examples of drugs examples of substances excess of plasma concentrations excessive anticholinergic effects excessive bradycardia excessive concurrent excessive digoxin levels excessive ethanol ingestion excessive fall excessive fecal loss excessive glucagon release excessive increase excessive neuromuscular weakness excessive perspiration excessive prolongation excessive widening exchange resin exchange resins excreted levels excretion ibuprofen excretion of amphetamine excretion of amphetamines excretion of barbiturates excretion of cefdinir excretion of cephalexin excretion of cobalt excretion of digoxin excretion of ethambutol excretion of fosfomycin excretion of fosinoprilat excretion of gabapentin excretion of loracarbef excretion of meclofenamate sodium excretion of methotrexate excretion of norfloxacin excretion of oxipurinol excretion of oxypurines excretion of quinidine excretion of thioethers excretion of urate excretion of verografin excretion rate excretory sites excystment rates exemestane pharmacokinetics exercise caution exercise testing exhibit characteristic apoptotic morphology exhibit doubling times existing hydrochlorothiazide therapy exjade pharmacokinetics exjade tablets exogenous co-factors exogenous enhancement exogenous estradiol exogenous respiration exogenously infused epinephrine expected lasma concentrations expected magnitude expected plasma concentrations expected plasma levels expensive drugs experience profile experienced tremor experienced users experimental animals experimental designs experimental soft-gelatin capsule formulation experimental toxic experiments reactions exposed histidine residues exposed histidines exposure levels exposure of cilostazol exposure of diazepam exposure of fexofenadine exposure of norethindrone exposure of omeprazole exposure of valdecoxib exposure of zaleplon exposure tonevirapine exposure-response relationships exposures of dexamethasone exposures of methylprednisolone exposures of norethindrone expression of subpopulations extended phenytoin sodium capsules extended release formulation extended release tablets extensive concomitant extensive intake extensive metabolism extensor tension extent of bioavailability extent of dissolution extent of flecainide extent of interaction extent of isradipine bioavailability extent of levetiracetam absorption extent of nateglinide protein binding extent of plasma protein extent of propranolol absorption external subcutaneous infusion pumps extra doses extracellular application extracellular ca extracellular levels extracellular rr extractable pancreatic insulin extraneals effects extrapyramidal symptoms extrarenal mechanisms extravasation reactions extreme agitation extrusion of potassium eye product facial wasting factor assays factor concentrates factor concentration factor iegs factor support factor synthesis factor treatment factrel test fade recovery faecalis atcc failing heart failing hearts failing human heart failure asa local factor failure of neomycin failure post-myocardial infarction fallopian tubes false elevations false-negative result false-positive direct coombs test false-positive direct coombs tests false-positive findings false-positive test false-positive urine test family education fat-soluble vitamins fatal adverse events fatal bleeding fatal cardiac arrests fatal convulsions fatal drug interactions fatal gastrointestinal hemorrhage fatal hepatic failure fatal prolongation fatal renal toxicity fatty acids favorable effects fecal blood loss fecal excretion fecal loss fed state feedback alterations felbamate concentrations felbamate daily doses felbamate dose felbamate treatment felbatol administration felbatol coadministered concentration felbatol phenytoin felbatol therapy felodipine plasma concentration-time curve female animals female cynomolgus monkeys female dog female fertility female hormones female monkeys female patient female patients female rats female subjects fenofibric acid fentanyl anesthesia fentanyl examples fentanyl plasma concentrations fentanyl transdermal system ferricyanide test ferrous sulfate fertility carcinogenesis pegasys fertility of humans fertility pegasys fetal abnormalities fetal development fetal immune system fetal toxicity fetal variations fewer drug interactions fewer extrapyramidal symptoms fewer infusion reactions fexofenadine auc fexofenadine gastrointestinal absorption fexofenadine gastrointestinal secretion fexofenadine hydrochloride fexofenadine pharmacokinetics fibrate drugs fibrates niacin fibric acid derivatives fibrinogen activity fibrosis therapies fifteen species filtration rate finasteride doses findings asymptomatic first hour first month first-line option first-line therapy first-pass metabolism first-pass metabolism of diltiazem first-pass metabolism of sirolimus five days five different ca five lacking kidney function five long-term experiments five men five normal volunteers five sedatives five times-day five-fold increase fivefold increase fixed daily dose fixed-interval fixed-ratio flecainide dosage flecainide elimination flecainide levels flecainide therapy flu remedies fluconazole administration fluconazole nevirapine fludrocortisone acetate fluid contents fluid transfers fluorescence test fluoride accumulation fluoride accumulation characteristic of animals fluoride levels fluoroquinolone antibiotic fluoroquinolones area fluoroquinolones arealso fluoxetine hydrochloride flupenthixol pharmacodynamics flurbiprofen absorption flurbiprofen concentrations flurbiprofen pharmacokinetics flurbiprofen pretreatment flurbiprofen time profiles fluvastatin administration fluvastatin bioavailability fluvastatin clearance fluvastatin plasma levels fluvoxamine exhibits fluvoxamine maleate fluvoxamine tablets fluvoxamine treatment folate concentration folate utilization fold increase fold increases fold prolongation folic acid antagonists folic acid supplements follow-up blood lipids follow-up liver function tests follow-up measurements follow-up of patients follow-up study fondaparinux sodium fondaparinux therapy food presentation food see clinical pharmacology foods fortified foods highly fortified force of contraction forevidence of withdrawal form chelates formal assessments formal clinical formal clinical drug interaction formal drug interaction formal drug-drug interaction formal drug-interaction formal drug-laboratory test interaction formal interaction formal interaction study formal pharmacokinetic formation of dapsone hydroxylamine formed cysts formoterol fumarate forms of contraception forms of drug abuse forms of magnesium deficit forms of memory formulation of fluorescence formulations of ciprofloxacin foscarnets tendency fosinopril sodium four antibiotics four chemotherapeutic agents four days four diets four doses four groups four healthy volunteers four hours four kinds four male wistar rats four murine models four patients four subjects four-day regimen fourteen days fourth group fraction of diclofenac fraction of drug fraction of fosphenytoin fraction of rat liver fraction of tolbutamide fractional clearance rate fractional inhibitory concentration index fractional mucosal cell accumulation fractional transfer free calcium ions free concentration free concentrations free cysteine free drug concentration free drug fraction free etodolac free fraction free fractions free hormone concentrations free levothyroxine free radical-mediated tissue damage free thyroxine free tiagabine concentration free valproate cmin concentrations free warfarin frequency of admissions frequency of attacks frequency of hyperkalemia frequency of rejection episodes frequency of seizures frequency of skin rash frequency requirements frequent prothrombin time-inr determinations frontal cortex fronti res frova treatment fruit juices fruit juices fruit full dose range full recovery fully formed cysts fully malignant behaviour fulminant pancreatitis fulminant rhabdomyolysis fulvestrant doses fulvestrant-treated lactating dams function hmg-coa reductase inhibitors function testing functional class functional class iv myocardium functional classes functional consequences functional coupling functional integrity functioning thyroid gland functions asa result fundus pulsation amplitude fungal infections fungal resistance furosemide administration furosemide clearance value furosemide tablets furosemide-stimulated diuresis future prospective future trends g of aspirin g-kg body weight gaba-ergic system gaba-positive drugs gabapentin administration gabapentin auc gabapentin concentrations gabapentin pharmacokinetic parameters gabapentin pharmacokinetics gallic acid galloyl esters gamma glutamyl transpeptidase gammaherpes virus ganglion-hypogastric nerve preparations ganglionic blocking agents ganglionic peripheral adrenergic blocking drugs ganglionic-blocking effect ganoderma lucidum ganoderma lucidum extract garlic capsules garlic capsules garlic gas chromatographic-mass spectrometer technique gastric acid secretion gastric acidity gastric fistulas gastric glands gastric hydrochloric acid secretion gastric secretion gastroduodenal ulcers gastrointestinal acidifying agents gastrointestinal adverse events gastrointestinal adverse experiences gastrointestinal agents gastrointestinal alkalinizing agents gastrointestinal bleeding gastrointestinal disturbances gastrointestinal effects gastrointestinal events gastrointestinal hemorrhage gastrointestinal irritation gastrointestinal lesions asa result gastrointestinal motility gastrointestinal secretion gastrointestinal side effects gastrointestinal toxicity gastrointestinal transit time gastrointestinal ulceration gefitinib metabolism gefitinib plasma concentrations gelatin capsules gelatinosa neurons gemfibrozil other fibrates niacin gene arc gene cassette gene expression gene transcription gene transfer general interactions generation of vasodilator genetic apparatus genetic data genetic factors genetic predisposition genetic variation genetically diabetic chinese hamster genetically initiated cell genetically nervous dogs genetically nervous e-strain subjects genetically predisposed mice genitourinary symptoms gentamicin therapy gentamycin-kg bwt geometric mean ratios geriatric population geriatric subjects geriatric use younger patients germinal centers gestational trophoblastic disease gestodene auc gi bleeding gi motility agent gi motility agents gi tract gibaldi etal ginkgo biloba ginsenosides response ginsenosides-induced inhibition given concurrently glatiramer acetate glaucoma drugs gleevec gleevec gleevec oral-dose clearance glipizide auc glipizide binds glomerular filtration glomerular filtration rate glucagon release glucocorticoid replacement glucocorticoid-induced gene expression glucocorticoid-induced gene transcription glucose cause renal glucose concentrations glucose control glucose dehydrogenase pyrroloquinolinequinone glucose enzymatic test glucose enzymatic test strip usp glucose intolerance glucose levels glucose metabolism glucose overload glucose oxidase glucose oxidase reactions glucose solution glucose tests glucose utilization glucose-specific method glucosyltransferase enzyme activity glucuronide metabolite glutamate receptor glutamatergic activation glutamic acid glutamic acid hcl glutamyl transpeptidase glutathione levels glyburide auc glyburide bid glyburide blood levels glyburide cmax glycemic control glycemic levels glyceryl trinitrate glycinergic inhibition glycopeptide-resistant enterococcus faecalis glycoprotein iib-iiia inhibitors glycosides enhanced possibility goal-directed behaviour gold medication gold salts gonadal steroid production gonadotropin levels gonadotropin peaks gonadotropin-releasing hormone grade iiia gradual dose increases gram negative bacteria gram of ethchlorvynol gram positive gram-negative bacilli gram-negative organisms gram-positive aerobic bacteria granulosa cell tumors grapefruit juice co-administration grapefruit juice co-administration of felodipine green tea gallocatechins green tea polyphenols grepafloxacin administration griseofulvin activity griseofulvin therapy gritty substance gross motor skills group drug interaction study group therapy groups of agents groups of experiments groups of patients groups of rats growing class growing problem growth factor treatment growth hormone growth hormone levels growth response gtp-binding proteins guardian section guardians of children guinea-pig vas deferens gut motility gvia-omega-agatoxin via-resistant h-labelled antigen h-spiroperidol binding h-triglyceride fractional clearance rate haart treatment haca titers haemagglutination assay haemodynamic compromise haemodynamic effects half-life of caffeine half-life of digoxin half-life of doxazosin half-life of doxycycline half-life of ertapenem half-life of felodipine half-life of fenoprofen half-life of flucytosine half-life of ketamine half-life of vardenafil half-lives of drugs haloperidol blocks dopamine haloperidol concentrations haloperidol levels haloperidol treatment haloperidol-treated patients halothane a-chloralose halothane anesthesia halothane anesthetic requirement hamster's alpha handling of drugs hard gelatin capsules harmonic mean elimination half-life hazardous activities hcl absorption hcl cream hcl plasma levels health organization criteria healthcare prescribers healthcare professional healthcare professionals healthcare providers healthy male hearing impairment heart association functional class heart failure asa local factor heart failure post-myocardial infarction heart function heart medicine heart problems heart rate increase heart stimulation heart-rate-lowering effects heat stimulus hematologic reactions hematopoietic system hemostatic defense heparin effect heparin sodium heparin sodium injection heparin therapy heparin-induced thrombocytopenia heparinized patients heparins effect hepatic blood flow hepatic clearance hepatic cyp hepatic disease hepatic drug extraction hepatic drug-metabolizing enzymes hepatic dysfunction hepatic enzyme induction hepatic enzyme inhibitors hepatic enzyme-inducing drugs hepatic enzymes hepatic failure hepatic function hepatic injury hepatic insufficiency hepatic lipid peroxidation hepatic metabolic clearance hepatic microsomal enzyme oxidation system hepatic microsomal enzyme system hepatic microsomal enzyme systems hepatic microsomal enzymes hepatic microsomal monooxygenase activities hepatic necrosis hepatic oxidation hepatic tissues hepatic toxicity hepatic transaminases hepatotoxic drugs hepatotoxic medications hepatotoxic potential hepatotoxic substances hepatotoxicity asymptomatic increases hepatotoxicity of acetaminophen hepatoxicity of ethanol herb interactions herbal preparations herbal product interactions herbal remedies herbal remedy herbal supplement st herbal therapy hereditary antithrombin iii deficiency heroin addiction heroin addicts heroin users heroin-related deaths hexanal-induced sleep hexokinase method high threshold voltage-dependent ca high-density lipoprotein cholesterol plasma levels high-density lipoproteins high-dose aspirin high-dose aspirin therapy high-dose cisplatin high-dose cyclosporin high-dose methotrexate high-dose salicylate therapy high-estradiol rats high-estradiol-treated rats high-frequency ventilation high-performance liquid chromatography highintersubject variability highly active antiretroviral therapy highly bound drugs highly fortified highly lethal dose highly plasma highly plasma protein highly potent cyp highly protein highly protein bound drugs highly protein-bound drugs highly sensitive assay system hind paw hindlimb digital extensor tension hippocampal adenylate cyclase activity hippocampal formation hippocampal lesions hippocampal level hippocampal system function histamine-induced gastric acid secretion histidine modification histidine residues histologic type historical data historicalcontrol group history of diabetes mellitus history of injection drug history of neoplasia history of neuropathy hiv disease hiv drugs hiv infection hiv protease inhibitors hiv status hiv-infected individuals hiv-infected patients hiv-infected subjects hiv-nhl patients hivid-associated adverse events hmg-coa reductase hmg-coa reductase inhibitor hmg-coa reductase inhibitor class hmgcoa reductase inhibitors homocysteine excretion rate homodimeric disintegrin homodimeric disintegrin contortrostatin homodimeric structure hoof twitch hormonal birth control products hormonal components hormonal contraception hormonal contraceptive ortho-novum hormonal contraceptives co-administration hormonal contraceptives differin their effectiveness hormonal evidence hormonal replacement hormonalmethods of birth control hormone action hormone activity hormone concentrations hormone levels hormone receptor-positive subpopulation hormone replacement therapy hormone response hormone status hormone synthesis hormone therapy hormone-binding globulin host defense hot-plate method hot-plate tests hour lag phase hour period hours after cholestyramine resin hours of administration hours of drug administration hours of treatment hplc peak hrs cmax auc hrs erythromycin human african trypanosomiasis human auc human bladder cancer cells human breast cancer cells human cells human cyp enzymes human diabetic human drug interaction human fungal infections human growth hormone human heart human heart failure human immunodeficiency human immunodeficiency virus human immunodeficiency virus-positive patients human insulin human liver human liver microsomal preparations human liver microsome human milk human p-glycoprotein human pharmacokinetic data human pharmacokinetics data human plasma human plasma area-under-the-curve human plasma protein human plasma proteins human recommended dose human red blood cells human response human serum human serum proteins human studies that toradol human subjects human therapeutic dose human trials human ventricular cardiac preparations human volunteers human weekly dose hydantoin antiepileptic hydatid cyst patients hydralazines serum concentrations hydroalcoholic solution hydroalcoholic solutions hydrocarbon anesthetics hydrocarbon general anesthetics hydrochloric acid secretion hydrochloride injection hydrochloride therapy hydrochlorothiazide therapy hydrocodone preparations hydrocortisone administration hydrocortisone pretreatment hydrogen breath test hydrogen maleate hydrolase carbamazepine hydrolase inhibitors hydrophilic molecule naflu hydrophobic sidechain hydroxide antacids hydroxide-containing antacid hydroxylamine treatment hydroxylated fenoprofen hydroxylation of coumarin hydroxymethylglutaryl coenzyme hypercholesterolaemic patients hypercholesterolemic noninsulin dependent diabetic patients hypercholesterolemic patients hyperglycemic effects hyperlactatemia-lactic acidosis hypersensitivity reactions hypertensive crises hypertensive crisis hypertensive nephropathy hypertensive patients hypertensive reactions hypertensive response hypertensive responses hyperthermia crisis hyperthyroid patients hyperuricemic effect hyperuricemic patients hypnotic agent hypnotic dose hypnotic drugs hypnotic medications hypo-prothrombinemic effect hypoglycemic effect hypoglycemic medications hypoglycemic requirements hypokalemic effect hypoparathyroid patients hypoprothrombinemic effect hypotension patients hypotensite effects hypotensive anesthesia hypotensive drugs hypotensive effects hypotensive episodes hypotensive response hypothalamic-pituitary-testicular axis hypothyroid patient hypothyroid patients hypoxic respiratory failure i-labelled antigen iatrogenic alteration iatrogenic alterations iatrogenic magnesium overload ibandronate osteoporosis treatment iboga alkaloid congener ibuprofen blood levels ibuprofen serum concentrations ibuprofen significantly affected prothrombin times identical insulin identification of drug interactions identified case idoxuridine preparation idv exposure ieg response iga glomerulonephritis iga-binding lectin ii clinical trial data ii diabetic patient ii pyrethroid ii receptor antagonists ii-vii-x complex iib-iiia inhibitors iii activity iii deficiency ileocecal junction imatinib concentrations imatinib plasma concentrations imatinib plasma concentrations drugs imidazole compounds imidazole drugs imipramine hydrochloride immediate release capsules immediate-early gene arc immediate-early genes immobilised cysteine immune function immune response immune system immune system development immuno-suppressant therapy immunoanalytical methods immunocompromised patients immunodeficiency virus immunodeficiency virus-positive patients immunodeficiency-associated lymphocyte disorders immunoreactive digoxin immunoreactive digoxin concentrations immunosuppressant agents concentration plasma concentrations immunosuppressants cyclosporin immunosuppressive drugs immunosuppressive therapies immunosuppressive therapy impact of chemotherapy impaired cardiac function impaired fertility impaired glucose tolerance impaired hypertensive patients impaired liver function impaired psychomotor impaired suppression impaired ventricular function impairment of acquisition impeding their absorption implant contraceptives implantable contraceptives implantable forms implanted albino rats implications of warfarin interactions importance of pharmacogenetics importance of topoisomerases important interaction improved glucose utilization in-creased circulating inaccurately low values inactivated vaccines inactive metabolites inadequate method inadequate numbers inadequate systematic experience incidence of akathisia incidence of cancer increases incidence of cancer metastasis incidence of hypertriglyceridemia incidence of infections incidence of melarsoprol reaction incidence of nephrolithiasis incidence of rashes incidence of sedation incidence of side effects incisive neuroleptics incomplete data incomplete depletion inconcomitant administration inconsistent reports increase absorption increase absorption of amphetamines increase atomoxetine steady-state plasma concentrations increase excretion increase excretion of amphetamines increase gefitinib plasma concentrations increase growth hormone levels increase imatinib concentrations increase of glycemia increase of phenobarbital level increase of serum potassium increase serum concentration increase serum concentration of amiodarone increased activity increased adverse effects increased anticoagulant effects increased anticoagulation effects increased appetite increased azithromycin serum concentrations increased bioavailability increased bleeding increased blood levels increased breakthrough bleeding increased bun increased cardiotoxicity increased catabloism increased catecholamine sensitivity increased cinacalcet exposure increased clearance increased clinical effects increased cns depressant effects increased cns depression increased deet toxicity increased dosage increased dosages increased dose increased drug concentrations increased effect increased effects increased exposure increased exposure tonevirapine increased exposures increased factors increased free concentrations increased frequency increased heart rate increased hepatotoxicity increased hypotension increased indinavir metabolism increased interaction increased intestinal permeability increased intracranial pressure increased intraocular pressure increased ketoprofen plasma clearance increased levels increased lidocaine concentrations increased lipid levels increased lithium plasma levels increased metabolism increased nephrotoxicity increased peak plasma concentration increased plasma concentration increased plasma concentrations increased plasma hdl increased plasma levels increased plasma quinidine concentrations increased plasminogen antigen increased platelet count increased possibility increased potential increased propranolol levels increased prothrombin increased prothrombin response increased prothrombin time increased prothrombin-proconvertin concentrations increased rate increased regional perfusion increased renal tubular secretion increased responsiveness increased risks increased sedation increased sedative effects increased serum concentrations increased serum digoxin concentrations increased serum enzyme activities increased serum haloperidol concentrations increased serum levels increased serum lithium levels increased serum potassium levels increased serum triglyceride increased severity increased sgot increased stability increased steady-state levels increased sulfobromophthalein retention increased susceptibility increased synaptic concentration increased thioether excretion increased thyroid-binding globulin increased toxicity increased urinary values increased vasoconstriction increased volume increases bioavailability increases enterohepatic elimination increases hydralazines serum concentrations increases inrifabutin exposure increases lithium plasma levels increases quinidine serum concentration increasing blood levels increasing concentration increasing incidence increasing metal concentration increasing salt intake increasing steady-state concentrations indandione derivatives indanedione anticoagulants indanyl sodium independent joint action index digoxin indications of magnesium indigestion remedies indinavir appropriate doses indinavir auc indinavir concentration indinavir concentration dose reduction indinavir concentration rifabutin indinavir concentration ritonavir indinavir concentrations indinavir dose indinavir indinavir appropriate doses indinavir metabolism indinavir pharmacokinetics indinavir plasma indinavir steady-state cmax indinavir therapy indinavir-based regimens indirect antiglobulin individual case individual cases individual compounds individual glucose concentrations individual inr values individual isoform individual patient response individual patients individual simulect clearance values individual subjects individual theophylline levels individualized fixed daily dose indocyanine green indoleacetic acid indomethacin blood levels induced therapeutic hypermagnesaemia inducer of cytochrome inducer of drug metabolism inducer rifampicin inducer rifampin inducers of drug clearance inducible vana antisense rna effect induction data induction of analgesia induction of apoptosis induction of glutathione-s-transferase induction of phosphorylation induction of tumors induction potential industrial workers ineffective therapy ineffectiveness of zaleplon infant formula infarction patients infarction setting infectious complications infectious disease infectious hepatitis inferior mesenteric ganglion-hypogastric nerve preparations inflammatory arthritis inflammatory disorders inflammatory reactions inflammatory recall reaction infliximab concentrations influence of calcium-channel blockers influence of coadministration influence of estradiol influence of midazolam influenzavirus vaccine information assists information digoxin information processing functions infrequent reports infused epinephrine infusion of arginine infusion of iloprost infusion of theophylline infusion pumps infusion rate infusion rate requirement infusion rate requirements infusion rates infusion reactions infusion requirements infusion site infusion solutions ingested acetaminophen ingested peginterferon ingestion of acitretin ingestion of alcohol ingestion of diclofenac ingestion of diphenidol ingestion of disulfiram ingestion of grapefruit inhalation aerosol inhalation anesthetics inhalation device inhalation dose inhalation general anesthetics inhalational anesthetics inhaled anesthetics inhaled ciclesonide inhaled medications inhibit aldehyde oxidase inhibit cyp inhibit drug transport systems lapatinib inhibit metabolism inhibiting activity inhibiting drugs inhibiting effects inhibition of antibody response inhibition of antipyrine elimination inhibition of celecoxib metabolism inhibition of cholinesterase activity inhibition of cimetidine inhibition of cytochrome p inhibition of erythrocyte acetylcholinesterase inhibition of fibrinolysis inhibition of metabolism inhibition of p inhibition of platelet aggregation inhibition of prostaglandin synthesis inhibition of response inhibitor benazepril inhibitor class inhibitor drug inhibitor ketoconazole inhibitor of aldehyde oxidase inhibitor of cytochrome inhibitor of iiia inhibitor phenelzine inhibitor selegiline inhibitor talk inhibitor therapy inhibitors cimetidine inhibitors cocaine inhibitors didanosine inhibitors felodipine inhibitors indinavir inhibitors maoi antidepressants inhibitors nefazodone cyclosporine large quantities inhibitors of cytochrome inhibitors of cytochrome p inhibitors of p inhibitory action inhibitory activity inhibitory concentration inhibitory concentration index inhibitory concentrations inhibitory drug interactions inhibitory effect inhibitory effects inhibitory potential inhibitory systems initial accutane prescription initiate therapy initiated cell initiated cells initiated murine cells initiation of alcohol initiation of carvedilol therapy initiation of carvedilol treatment initiation of diclofenac therapy initiation of rifampin initiation of therapy injectable benzodiazepines injectable lorazepam injected ketamine injected mice injection clonidine injection concentrate injection drug injection of beta-endorphin injection of cimetidine injection of estradiol injection of ketamine injection of naloxone injection of perchlorate injection of phencyclidine injection of radiopertechnetate injection of thiosulfate injection of trichlorfon injection of vehicle injection site injection site reaction injection site reactions injection therapy injections of bombesin injections of saline injections of trimethyl lead injections of verapamil innovar anesthesia innovar vet inorganic cations inotropes milrinone inotropic agents inotropic effects inotropic properties input impedance inr values inrifabutin exposure instances of drug interactions instances of dyspnea instances of rash insufficient experience insufficient magnesium intake insufficient plasma insulin absorption insulin concentrations insulin dosage insulin dose adjustment insulin levels insulin parameters insulin preparations insulin release insulin requirement insulin resistance insulin secretion insulin sensitivity insulin sensitizers insulin therapy insulin-dependent diabetic patients insulin-induced hypoglycemia insulin-induced proliferation insulin-sensitizing effects insulins ability intact endothelium intact liver blood flow intact subjects intake of alcohol intake of cholestyramine intake of furosemide intake of grapefruit juice intake of mineral oil intensified electrolyte depletion intensive care units intensive control intensive monitoring inter-patient variability inter-patient variation interacting drug interacting drugs interacting mechanisms interaction asa result interaction captopril interaction data interaction effects interaction fosinopril interaction information digoxin interaction of aripiprazole interaction of cephalexin interaction of clindamycin interaction of dirithromycin interaction of efavirenz interaction of ethanol interaction of gentamycin interaction of jacalin interaction of ketamine interaction of prostaglandin interaction sites interaction studies drug name effect interaction trials interactions acetaminophen interactions albuterol interactions amerge tablets interactions asa result interactions bisphosphonates interactions blood glucose interactions cephalosporins interactions certain endocrine interactions cimetidine interactions corticosteroids interactions dactinomycin interactions danazol interactions diltiazem interactions dofetilide interactions effect interactions false elevations interactions finasteride interactions frova interactions hyperaminotransferasemia interactions increases interactions lovastatin interactions mylotarg interactions naproxen interactions of carvedilol interactions of cobalt interactions of coumaphos interactions of erythromycin interactions oral contraceptives keppra interactions phenytoin interactions positive direct coombs tests interactions see clinical pharmacology interactions serum salicylate assays interactions several drug interaction interactions terfenadine interactive effect interations sulfapyridine intercurrent ethanol intercurrent illnesses interference of antidepressants interference of biocytin interferometric measurement interferon beta interferon induction interferon induction data interindividual pharmacokinetic variability interindividual variability intermediate doses intermenstrual bleeding intermittent haemodialysis internal application international literature international normalized ratio international pharmaceutical abstract interoccasion variability interpretation of serum interpretation oft interresponse times interruption of therapy intersubject variability interval caution interval prolongation intestinal adenocarcinomas intestinal adsorbents intestinal beta-glucuronidase intestinal cancers intestinal carcinogenesis intestinal digoxin absorption intestinal first pass intestinal lumen intestinal microflora intestinal mucosa intestinal permeability intestinal permeation intestinal transits intestinal tumors intracellular ca intracellular exposure intracellular mobilization intracellular phosphorylation intracellular resistance intracisternal injection intracranial hypertension intracranial pressure intraluminal concentrations intramuscular doses intramuscular injection intramuscularly injected ketamine intranasal ciclesonide intraocular pressure intraperitoneal doses intraperitoneal injections intrathecal administration intrathecal injection intrathecal naloxone intrathecally administered methotrexate intravascular catabolism intravascular volume depletion intravenous adenocard intravenous administration intravenous agents intravenous alefacept intravenous aminoglycosides intravenous amiodarone intravenous amphetamine intravenous application intravenous bolus injections intravenous calcium antagonists intravenous dantrolene sodium intravenous dose intravenous drug intravenous fenoldopam intravenous hydration intravenous iloprost intravenous injection intravenous misuse intravenous morphine intravenous opiate intravenous pentamidine intravenous placebo intravenous prodrug intravenous prodrug form intravenous ranitidine intravenous route intravenous self-administration intravenously administered famotidine intravenously administered labetalol hcl intraventricular beta-endorphin intraventricular injection intraventricular morphine intrinsic anticonvulsant effect intrinsic value introduced atypical antipsychotic introduction of chloroquine introductory chapter intubating dose inulin method invasion of adenocarcinomas invirase-ritonavir drug class involving alprazolam iodamide excretion iodamide transport iodinated cholestographic agents iodinated contrast media iodine deficiency iodine excess iodine-containing products iodometric titration ionized calcium ionized species ip injections ipratropium bromide irbesartan administration irbesartan metabolites iressa therapy irinotecan concentrations iron absorption iron balance iron chelator therapies iron concomitant administration iron contents iron supplement iron supplements iron-containing preparations iron-fortified breakfast cereals iron-fortified infant formula irrational behaviour irregular heartbeat irreversible braindamage ischemic response ischemic stroke iso-sensitest broth isocaloric solution isoenzyme family isoenzyme system isoenzyme system fentanyl isoenzymes carbamazepine isoflurane anesthesia isoform selective marker substrates isoforms cyp isolated cases isolated myocardial membranes isolated rabbit isolated single pancreatic acinar cells isolates of mycobacterium ulcerans isomers of warfarin isoproterenol hydrochloride injection isosorbide dinitrate isosorbide mononitrate isozyme activity isradipine bioavailability isradipine concentrations isradipine levels isradipine mean peak plasma concentrations isradipine therapy itraconazole calcium channel blockers diltiazem itraconazole co-administration itraconazole indinavir concentration dose reduction itraconazole ketoconazole drug interaction itraconazole plasma concentrations itraconazole therapy iv ace inhibitors iv attenuate potassium loss iv methylprednisolone dose iv myocardium iv vasodilators jaff reaction jaffe reaction jejunal net fluid transfers job appointments joint action joint action data joint dose-response curves joint exposure joint injuries juice co-administration juices fruit kappa opioid kappa-selective opioids kda adapter protein ketoconazole concentrations ketoconazole dose ketoconazole drug interaction ketoconazole fexofenadine ketoconazole indinavir concentration dose reduction ketoconazole ketoconazole nevirapine ketoconazole nevirapine ketoconazole plasma concentrations ketoconazole tablets ketone bodies ketone test ketoprofen doses ketoprofen plasma clearance ketoprofen protein ketoprofen treatment ketorolac plasma concentrations ketorolac plasma levels ketorolac tromethamine ketorolac tromethamine protein binding key pharmaceuticals kht tumour ki value ki values kidney allograft recipients kidney cell cultures kidney damage kidney diseases kidney function kidney homogenates kidney recipients kidney rejection kidney slices kinds of antibiotics kinetic characteristics klebsiella oxytoca known cyp l-arginine supplements lab tests labeling index labetalol hcl labetalol metabolites laboratories platelia aspergillus eia test laboratory abnormalities laboratory assessments laboratory evidence laboratory evidence of hypothyroidism laboratory monitoring laboratory parameters laboratory test abnormalities laboratory test alterations laboratory test findings asymptomatic laboratory test interactions laboratory test interactions amerge tablets laboratory test interactions asa result laboratory test interactions certain endocrine laboratory test interactions mylotarg laboratory testing laboratory tests interactions hyperaminotransferasemia laboratory tests response lack of anti-platelet effect valdecoxib lack of antibody response lack of correlation lack of interaction lack of platelet effects lacking kidney function lactating dams lactulose hydrogen breath test lactulose-induced drop lag phase lamivudine concentration lamivudine pharmacokinetics lamivudine phosphorylation lansoprazole delayed-release capsules lapatinib concentrations laser interferometric measurement lasma concentrations lasting depletions lasting inhibition latent complications latent diabetes mellitus latent lcv infection laxative action lcv infection ldl cholesterol concentration ldl-c reduction lean animals lean rats leflunomide treatment lenalidomide administration leprosy-associated inflammatory reactions lesions asa result lessened active metabolite formation lethal dose lethal doses letrozole plasma levels leukocyte production leukocyte transfusions leukopenic activity leustatin injection levamisole hydrochloride level determinations levels carbamazepine levels of caffeine levels of catecholamines levels of ciclesonide levels of corticosteroid-binding globulin levels of cortisol levels of creatinine levels of dopamine levels of drugs levels of everolimus exposure levels of fibrinogen levels of homocysteine levels of serotonin levels-effects of chlorpheniramine levels-effects of ethinylestradiol levetiracetam absorption levobupivacaine levels levodopa-dopa decarboxylase inhibitor levodopa-dopa-decarboxylase inhibitor levofloxacin-oxycodone regimens levonorgestrel-treated rats levorotatory isomer levothyroxine sodium levothyroxine sodium absorption levulan kerastick leydig cell tumors lidocaine anticonvulsants carbamazepine lidocaine concentrations life-threatening cardiac arrhythmias life-threatening cardiac dysrhythmias life-threatening conditions life-threatening drug interactions life-threatening interactions life-threatening reactions life-threatening situations life-threatening ventricular arrhythmias ligand binding activity light-dark test likelihood of bone marrow depression limb digital extensor tension limb injury limbic function limbic integration limbic system limit values limited clinical data limited clinical experience limited comparative data limited data limited evidence limited experience limited inhibitory activity limited pk limited renal excretion limited sampling linear logarithmic fashion linear regression lipid levels lipid metabolism lipid peroxidation lipid profile lipid response lipid-lowering activity lipid-lowering drugs lipolytic activity lipoprotein cholesterol levels lipoprotein cholesterol plasma levels liquid antacid liquid chromatographic assay liquid chromatography liquid impinger listed agents listed isoforms lists of drugs literature article literature case lithium clearance lithium concentration lithium concentrations lithium dose lithium excretion lithium intoxication lithium levels lithium plasma levels lithium preparation lithium preparations lithium prophylaxis lithium renal clearance lithium reversible increases lithium salts lithium serum clearance lithium serum concentrations lithium treatment lithium-a drug interaction study lithiums renal clearance live attenuated vaccines live bacteria live typhoid vaccines live-attenuated vaccines liver alt liver aminotransferases liver biopsy liver blood flow liver cytochrome liver damage liver disease liver enzyme abnormalities liver enzyme elevations liver enzymes liver function liver function testing liver function tests liver injury liver metabolic activation factor liver microsomal preparations liver microsome liver transaminases liver tumors liver weight local anesthesia local anesthetic agents local breast cancer recurrence local factor local irritation locomotor activities locomotor activity locomotor effects locomotor responses lodine treatment logarithmic fashion logical approach logistic probability distribution logistic regression models logs of reduction lomefloxacin pharmacokinetics long acting nitrates long half-lives long lasting depletions long lasting inhibition long periods long study long surgical procedures long withdrawal period long-acting benzodiazepine long-acting benzodiazepines long-acting nitrates long-lasting behavioral effects long-sedation time long-term administration long-term anticonvulsant therapy long-term carcinogenicity long-term consequences long-term experiments long-term safety long-term suppression long-term warfarin therapy longitudinal assessment longitudinal stability longterm treatment loop technique lopinavir concentration lopinavir-ritonavir lopinavir lopinavir-ritonavir lopinavir concentration loratadine descarboethoxyloratadine erythromycin loratadine relative lorazepam injection losartan concentration loss medications loss of bar-press response loss of blood glucose control loss of efficacy loss of microtubules loss of spermatozoa loss of symptom control lovastatin auc lovastatin therapy lovenox injection therapy low initial dosing low-density lipoprotein cholesterol levels low-density lipoproteins low-dose aspirin low-dose combination oral contraceptives low-dose dopamine hcl low-dose ritonavir low-levels of exposure low-molecular weight lower auc lower seizure threshold lower serum flurbiprofen concentrations lowered blood levels lowered numbers lowered plasma concentrations lowered serum theophylline concentrations lst mice lucidum extract luciferase reporter gene lunch doses lung surfactant luteinizing hormone lymph nodes lymphatic invasion lymphocyte counts lymphocyte disorders lymphoid malignancy lymphoma cells maalox administration maalox tc maalox tc suspension mac isoflurane macrolide class macrolide immunosuppressant macrolide products macrovascular cardiovascular disease magnesium deficiencies magnesium deficiency magnesium deficit magnesium depletion magnesium doses magnesium hydroxide-containing antacid magnesium hydroxides magnesium infusions magnesium intake magnesium levels magnesium load magnesium overload magnesium salicylate magnesium status magnesium sulfate magnesium supplementation magnesium therapy magnesium trisilicate magnesium-aluminum hydroxide magnesium-aluminum-containing antacid products magnesium-choline salicylate magnesium-containing antacids magnitude of interaction magnitude of response mainly metabolized maintain the prothrombin time-inr maintenance bolus doses maintenance dose maintenance dose of digoxin maintenance dose of warfarin maintenance doses maintenance doses of warfarin maintenance level maintenance of treatment response maintenance schedule maintenance thyroid replacement therapy major cyp enzyme malabsorption of vitamin male adult wistar rats male animals male dogs male fertility male hormones male lean male partners male rhesus monkeys male sprague-dawley rats male wistar rats malignant behaviour malignant cells malignant disease malignant hyperpyrexia malignant hyperthermia crisis malignant phenotype malignant syndrome maltose interference mammalian cell mutation assay mammalian liver metabolic activation factor mammalian target mammary gland mammary tumour virus gene expression mammary tumour virus promoter management of angina management of infection management of patients management of schizophrenia manic-depressive disorder manic-depressive illness mansoni miracidia mao inhibitor class mao inhibitor phenelzine mao inhibitor selegiline mao inhibitor talk mao inhibitors maoi antidepressants mao-b inhibitor selegiline maoi antidepressants marine coelenterates marked effect marked hyperkalemia marked hypertension marked inhibition marked interference marked reductions markedly increased plasma concentrations marker substrates marketed chewable-dispersible tablet formulation marketing experiences marketing observations marrow depression marrow erythrocytes marrow function marrow megakaryocytes marrow suppression marrow suppression warrants consideration marrow toxicity marrow toxicity of patients maternal serum levels mathematical functions matrix protein condensation matrix protein reorganization maximal acetylcholine-induced vasorelaxation maximal decrease maximal effect maximal effects maximal exercise testing maximal hypotension maximal plasma concentrations maximum block maximum calculated theophylline clearance maximum concentration maximum cumulative doses maximum human dose maximum human therapeutic dose maximum plasma concentration maximum plasma concentrations maximum potassium levels maximum qtc increase maximum relaxation mayuse rifabutin mcg combination mcg of ethinylestradiol mean auc values mean aucs mean change mean cmax digoxin mean gabapentin auc mean increase mean inr values mean lovastatin auc mean phenytoin auc mean qtc interval meaningful drug interactions meaningful increases meaningful interactions meaningful reductions measurable effect measurable limit measured psychomotor measurement of amiodarone serum concentration measurement of amprenavir measurement of creatinine measurement of fundus pulsation amplitude measurement of nociception measurement of serum measurement of serum creatinine levels measurement of serum digoxin levels mec values mechanism of causation mechanism of coagulation alterations mechanism of interaction mechanism of milk ejection mechanisms of action mechanisms of insulin resistance mechanisms of metal toxicity meclofenamate sodium meclofenamate sodium absorption meclofenamate sodium plasma levels meclofenamic acid medial survival median follow-up median survival median tmax median-effect model medical attention medical backgrounds medical complications medical considerations medical examinations medical intervention medical literature medical practice medical records medication authorization cards medication review medicine certain antibiotics medroxyprogesterone acetate mefenamic acid mefloquine administration mefloquine therapy melarsoprol cure melarsoprol reaction membrane phospholipids membrane potential membrane properties membrane properties of rat membrane sterol memory function memory system memory systems menstrual cycle irregularities menstrual cycles menstrual period menstrual rhythm mental alertness mepron suspension mercapturic acids mesenteric arteries mesenteric ganglion-hypogastric nerve preparations mesenteric resistance arteries mesenteric vasodilation mesylate tablets metabolic abnormalities metabolic activation metabolic activation factor metabolic disturbances metabolic drug interactions metabolic effects metabolic enzymes metabolic inhibitors metabolic interactions metabolic interference metabolic probe study metabolic profiles metabolic rate metabolic reactions metabolic responses metabolic status metabolism of amiodarone metabolism of antipyrine metabolism of astemizole metabolism of bexarotene metabolism of bupropion metabolism of carbamazepine metabolism of cevimeline metabolism of chloroquine metabolism of chlorpromazine metabolism of clofarabine metabolism of combination metabolism of compounds metabolism of corticosteroids metabolism of cyclosporine metabolism of cytochrome p metabolism of dasatinib metabolism of dexamethasone metabolism of docetaxel metabolism of drugs metabolism of ergotamine metabolism of escitalopram metabolism of estazolam metabolism of ethinylestradiol metabolism of gefitinib metabolism of levobupivacaine metabolism of methylxanthines metabolism of phenytoin metabolism of prednisolone metabolism of progestins metabolism of quetiapine metabolism of saquinavir metabolism of terfenadine metabolism of theophylline metabolism of vardenafil metabolism of warfarin-type anticoagulants metabolite concentration metabolite concentration indinavir metabolite concentrations metabolite concentrationswere metabolite desmethylastemizole metabolite desmethylastermizole metabolite doxorubicinol metabolite formation metabolite of carbamazepine metabolite of chloroprocaine metabolite of dapsone metabolite of irinotecan metabolite of leflunomide metabolite of mycophenolate metabolite of terfenadine metabolite of vitamin metabolites of capecitabine metabolites of etodolac metabolized drugs metabolized statins metabolizers of debrisoquin metabolizers of drugs metabolizing enzyme metabolizing enzymes metabotropic glutamate receptor metal cations metal concentration metal mixture toxicity investigation metal mixtures metal toxicity metformin pharmacokinetics meth administration methadone concentration coadministration methadone dose methadone levels methadone methadone concentration coadministration methadone methadonea methadone levels methadonea methadone levels methamphetamine administration methenamine therapy methenamine therapy urinary excretion method of barrier contraception method of contraception method of contraception inwomen methods toxi-lab methotrexate accumulation methotrexate activity methotrexate clearance methotrexate concentrations methotrexate doses methotrexate lodine methotrexate plasma concentrations methotrexate renal tubular transport methotrexate therapy methotrexate vioxx methotrexate-related toxicity methylergonovine contraindicated methylprednisolone aprepitant methylprednisolone dose metoprolol antihistamines carbamazepine metoprolol plasma levels metyrapone test metyrapone tests mg dose of anagrelide mg dose of aspirin mg dose of cefditoren pivoxil mg dose of doxazosin mg dose of isradipine mg dose of loratadine mg dose of terazosin mg dose of tiagabine mg doses of cephalexin mg of allopurinol mg of azithromycin mg of caffeine mg of cimetidine mg of coumaphos-kg mg of coumaphos-kg-day mg of diazepam mg of didanosine mg of dideoxyinosine mg of felbamate mg of fexofenadine hydrochloride mg of fluconazole asa mg of indinavir mg of ketoprofen mg of lenalidomide mg of midazolam mg of norethindrone mg of norethindrone acetate mg of phenobarbital sodium-kg mg of ranitidine q mg of rofecoxib mg of tolbutamide mg of warfarin mg-d of tolbutamide mg-day lexapro mg-day monotherapy mg-day of azithromycin mg-day of felbamate mg-day of ketoconazole mg-day of rifampin mg-day racemic citalopram mg-kg body weight mg-kg dose mg-kg doses mg-kg egg weight mg-kg enhanced verografine mg-kg of ketamine mg-kg of metabolite mg-kg-day of cromolyn sodium mg-kg-day of diflunisal-acetaminophen mg-kg-day of isoproterenol mhd concentration miconazole nitrate micro-dosed progesterone preparations micrococcus luteus microdilution method microdosed minipill progestin preparations microdosed progestin minipill preparations microdosed progestin-containing minipill preparations microg-kg body weight micrograms of lectin micronucleus test microsomal drug microsomal drug metabolism microsomal enzyme inducer microsomal enzyme oxidation system microsomal enzyme system microsomal enzyme systems microsomal fraction microsomal monooxygenase activities microsomal preparations microtitre method microvascular complications midcycle gonadotropin peaks middle-aged subjects migraine patients migraine therapy mild decrease mild uncomplicated hypertension mild-to-moderate inhibitors miles laboratories milk ejection milk products milk secretion millions of men min interval mineral density mineral oil mineral oil-concomitant intake minimal alterations minimal bactericidal concentration minimal effects minimal essential tissue culture minimal experimental designs minimal inhibitory concentration minimal inhibitory concentrations minimum alveolar concentration minimum effective concentration minimum inhibitory concentration minimum inhibitory concentrations minimum lithium concentration minipill preparations minipill progestin preparations minus pyridoxine minutes of exposure minutes of hypnosis miotic actions misleading information mitogenic activity mitogenic effect mixed agonist-antagonist opioid analgesics mixed opioid agonist-antagonist effects mixed signalled-unsignalled differential-reinforcement-of-low-rates mixed-function mono-oxidases mixed-function oxidase enzyme mixing novolog mixture toxicity investigation mixtures of cadmium mobilization of calcium ions mode of action model lung surfactant model peptide drugs model peptide drugs bacitracin moderate activity moderate cyp moderate doses moderate hypertension moderate inducer moderate renal impairment modern medications modest degree modest dysphoria modest effect modest elevations modest increases modest inhibition modification of surface histidine residues modification of toxin modified histidine residues modulatory effect moieties of threohydrobupropion molecular basis molecular differences molecular level molecular mechanisms molecular weight heparins molecule naflu monitor serum potassium levels monitoring of anticonvulsant plasma levels monitoring of blood glucose monitoring of pancreatitis monitoring of prothrombin time monitoring of pulse monitoring of serum cyclosporin level monitoring of serum lithium levels monitoring of serum potassium monitoring of serum theophylline concentrations monitoring of tacrolimus blood concentrations monitoring of theophylline plasma concentrations monoamine oxidase inhibition monoamine oxidase inhibitor monoamine oxidase inhibitory effects monoamine oxidases monoclonal antibodies monomeric disintegrins echistatin monomeric members mononuclear cell infiltration mononuclear cells monooxygenase activities month of therapy mood states more specific applications moribund condition morphine analgesia morphine blood levels morphine capsule morphine pharmacokinetic parameter values morphine prolonged gastrointestinal transit time morphine-experienced rats morphine-induced increases morphine-induced locomotion morphine-induced tail-flick inhibition morphological markers mothers fulvestrant motility agent motility agents motility dysfunction motion sickness medications motor blockade motor effects motor effects of alcohol motor skills motor weakness mouse carcinogenicity study mouse lines mouse lymphoma cells mouse mammary tumour virus promoter mouse model mouse tumour mouth sores movement of calcium ions mptp administration mptp-induced neuronal damage mrna level mtc-mdp bone scintigraphy mtc-methylene diphosphonate mucosal accumulation mucosal cell accumulation mucosal cells multidrug-resistant organisms multiple dose multiple dose administration multiple dose study multiple dose treatment multiple dosing multiple effects multiple enzyme systems multiple exposure multiple fixed-interval fixed-ratio multiple forms multiple interacting mechanisms multiple medication multiple medications multiple occupational exposure multiple oral doses multiple routes multiple sclerosis patients multiple-dose administration multiple-dose crossover study multiple-dose fluoxetine multiple-dose interaction multiple-dose pharmacokinetic profiles multiple-dose regimens multiple-dose study multivalent cation-containing products multivalent cations multivitamin preparations multivitamins quinolones form chelates murine cells murine models muscle biopsy muscle cell muscle cells muscle pains muscle relaxant muscle relaxant antagonists muscle relaxant drugs muscle relaxant effect muscle relaxant effects muscle relaxant effects of aminoglycosides muscle relaxants birth control pills muscle sprain muscular fatigue musculoskeletal adverse events mutagenesis impairment mutagenesis pegasys mutagenicity assay mutation assay mutual inactivation myasthenic patient myasthenic weakness mycobacterium ulcerans mycobacteriumavium-intracellulare complex mycophenolate mofetil myelosuppressive agents myocardial depressants myocardial function myocardial infarction patients myocardial infarction setting myocardial injury myocardial ischaemias myocardial membranes myocyte membranes n-demethylated metabolite n-multistix sg dipstick test nafarelin acetate nalidixic acid nalidixic acid administration naloxone-sensitive endorphinergic system name clinical comment antiarrhythmics name effect name effect clinical comment clarithromycin naproxen anion naproxen anion plasma levels naproxen sodium naproxen sodium capsules narcotic pain medication narcotic withdrawal syndrome narrow therapeutic index digoxin nasal congestion nasal drops nasal spray nasal vasoconstrictor nateglinide protein binding natriuretic effect natriuretic effect of furosemide nefazodone cyclosporine large quantities negative bacteria negative chronotropic effects negative consequences negative inotropic agents negative inotropic effects negative inotropic properties negative result negative symptoms nelfinavir incombination nelfinavir indinavir concentration nelfinavir plasma nelfinavir plasma auc nelfinavir plasma concentrations nelfinavir steady-state cmax neomycin administration neomycin sulfate neomycin sulfate neuromuscular blocking effects neonatal period neoplastic disease nephrotoxic agents nephrotoxic compounds nephrotoxic drugs nephrotoxic medications nephrotoxic potential nerve damage nerve degeneration nerve endings nerve preparations nerve transmission nerve vacuolation nervous e-strain subjects nervous system depressants net change net decrease net effect net effects net fluid transfers neural pathways neural plasticity neurobiological alterations neurocysticercosis patients neuroeffector defects neuroleptic clozapine neuroleptic drugs neuroleptic malignant syndrome neuroleptic therapy neuroleptics dosage neurologic disorders neurological complications neurological effects neurological toxic effects neurological toxicity neuromuscular blockers neuromuscular blocking agents neuromuscular blocking effects neuromuscular blocking properties neuromuscular junction neuromuscular paralysis neuromuscular weakness neuron blockade neuronal apparatus neuronal cells neuronal damage neuronal reuptake neuronal uptake neuropsychiatric events neurotoxic drug therapy neurotoxic effect neurotoxic side effects neurotoxin serotypes neutralizing agent neutropenic effect neutrophil count neutrophil counts nevirapine antithrombotics warfarin potential effect nevirapine drug class examples nevirapine indinavir concentration nevirapine plasma concentrations nevirapine regimens nevirapine therapy nevirapine-associated adverse events next hour nicardipine hcl nicardipine hcl absorption nicotine replacement nicotine transdermal system nicotine-induced dopamine release nicotinic receptors niddm subjects nifedipine plasma levels nifedipine therapy nimodipine plasma concentrations nimodipine-omega-conotoxin gvia-omega-agatoxin via-resistant ninds t-pa stroke trial nine patients nisoldipine plasma concentrations nitrate therapy nitric oxide donor compounds nitrobluetetrazolium test nitrofurantoin serum levels nitrogen mustard nitrosourea auc nitrosourea ccnu nitrosourea peak concentrations nitrous oxide nitrous oxide-oxygen nizoral tablets nmda receptors nmda-ergic activation nnrti-based regimens nodal conduction node conduction node function nodular acne non-aspergillus polysaccharides non-aspirin drug non-comparative clinical trial non-depolarizing muscle relaxants non-diabetic rats non-diabetic subjects non-gastrointestinal bleedings non-hodgkin lymphoma non-human primates non-ionized species non-linear pharmacokinetics non-matched historicalcontrol group non-myelinated axons non-narcotic analgesics non-nucleoside reverse transcriptase inhibitor non-nucleoside reverse transcriptase inhibitors non-opioid agonist effects non-opioid analgesics non-pegylated interferon non-potassium sparing diuretics non-renal clearance non-selective beta-adrenergic-blocking agents non-selective mao inhibitor non-selective mao inhibitors non-selective monoamine oxidase non-significant increases non-specialist hospitals non-steroidal anti-inflammatory agent non-steroidal anti-inflammatory agents non-steroidal anti-inflammatory drug indomethacin non-steroidal anti-inflammatory drugs non-steroidal antiinflammatory drugs nonabsorbable antacids nonabsorbable complex nonadditive independent joint action nonbarbiturate hypnotics nonbenzodiazepine agonists noncardioselective beta-blockers nonclinical data nondepolarizing muscle relaxants nondepolarizing neuromuscular blocking agents nondrug reinforcer nonfailing heart nonfailing myocardium nonfunctioning thyroid gland nonhormonal contraceptive product noninsulin dependent diabetic patients nonlethal dose nonlethal dose of endotoxin nonlinear kinetic characteristics nonlinear regression model nonlinear weighted least squares approach nonopioid tolerant patients nonprescription products nonrenal clearance nonselective inhibitor nonselective monoamine oxidase inhibitors nonsignificant increases nonsteroial anti-inflammatory drugs nonsteroidal agents nonsteroidal anti-inflammatory drug nonsteroidal anti-inflammatory drug fenbufen nonsteroidal antiinflammatories nonsteroidal antiinflammatory agents nonsteroidal antiinflammatory drug nonzero background response noradrenaline storage vesicles noradrenaline-precontracted arteries norepinephrine receptors norepinephrine release norepinephrine reuptake norepinephrine uptake sites norepinephrine-induced platelet aggregability norepinephrine-induced platelet aggregation norethindrone acetate norethindrone oral contraceptives norethindrone plasma concentrations norethindrone-ethinyl estradiol normal antiasthmatic dose normal cells normal daily activities normal dogs normal dose normal doses normal fat digestion normal healthy male normal healthy volunteers normal insulin release normal levels normal male normal menstrual rhythm normal metab-olizers normal rates normal renal function normal saline normal tissue normal tissues normal value normal variability normal volunteers loratadine descarboethoxyloratadine erythromycin normalized ratio normovolemic healthy subjects north american clinical trials north american trials northern blot analysis nortriptyline hydrochloride novo kidney allograft recipients novo renal transplant recipients nph human insulin nsaid users nsclc patients nucella lapillus nuclear matrix protein condensation nuclear matrix protein reorganization nucleoside analogues nucleoside analogues didanosine co-administration nucleoside-experienced patients nucleotide release nucleus accumbens nueronal cell body numbers of colony numbers of patients numbers of subjects numerous drug interactions numerous liver tumors numerous potentiation effects numerous preparations nursing infant nursing infants nursing mothers nursing mothers fulvestrant nutrient absorption nutrition support nutritional supplement nyha class obese rats objective responses observation period observed efavirenz plasma concentrations observed effects observed increase observed training-induced neurobiological alterations obstetric blocks obstructive pulmonary disease occasional doses occasional literature reports occasional susceptible patients occult blood occupational exposure occurrence of myelotoxicity occurrence of osteomalacia occurrence of torsade ocular blood flow ocular circulation ocular effects ocular parameters ocular vasodilation oculo-bulbar myasthenia gravis ofthe drug oil-concomitant intake olanzapine treatment omega-agatoxin iva omega-agatoxin iva-sensitive omega-conotoxin gvia omega-conotoxin gvia-sensitive omeprazole pharmacokinetics omnicef therapy on different days on-treatment additive toxicity one hour one month one-stage coagulation assays one-stage factor assays one-stage prothrombin time one-week course of cimetidine operated animals operating dangerous machinery operating machinery ophthalmic cholinesterase inhibitors ophthalmic solution ophthalmic suspension opiate agonists fentanyl examples opiate analgesics opiate withdrawal opioid agonist-antagonist effects opioid agonists opioid analgesia opioid analgesic opioid anitagonism opioid antagonist opioid containing medicines opioid dose opioid responses opioid withdrawal signs opioid-dependent patients opioid-evoked hyperpolarization opioid-induced gastrointestinal effects opportunistic infection opportunistic infections opposite directions opposite nostrils optic nerve degeneration optic nerve vacuolation optimal care optimal conditions optimal designs optimal dose optimal dosing interval optimal pharmacokinetics optimal pulmonary function optimal therapeutic dose optimal treatment outcome optimum therapeutic blood levels or guardian oral absorption oral ace inhibitors oral adl oral administration oral agents oral alendronate oral allopurinol oral amiodarone oral anticoagulahts oral anticoagulant oral anticoagulant agents oral anticoagulant response oral anticoagulant therapy oral anticoagulant warfarin oral anticoagulants caution oral anticoagulants interaction oral anticoagulents oral antidiabetes products oral antidiabetic agents oral antidiabetic drugs oral antidiabetic products oral antidiabetics oral antifungal agents oral azole antifungal oral bioavailability oral bronchodilators oral budesonide oral calcium antagonists oral calciumantagonist oral carbonic anhydrase inhibitors oral ccnu oral ccnu cytotoxicity oral ccnu pharmacokinetics oral cimetidine oral clearance oral clearance values oral clonidine oral cobalt oral combination oral conivaptan oral contraception oral contraceptive agents ethinylestradiol oral contraceptive cycles oral contraceptive norethindrone-ethinyl estradiol oral contraceptive product oral contraceptive regimen oral contraceptive users oral contraceptives ethinylestradiol oral contraceptives keppra oral contraceptives multiple doses oral contraceptives rofecoxib oral cordarone administration oral cypermethrin administration oral dapsone treatment oral dexamethasone doses oral dose oral doses oral erection-supporting medication oral erythromycin oral etoposide oral form oral formulation oral formulations oral ganciclovir oral gemifloxacin oral glucose overload oral haloperidol oral hormonal contraceptive ortho-novum oral hypoglycemic agents oral hypoglycemic requirements oral ketoconazole oral live typhoid vaccines oral magnesium doses oral magnesium load oral magnesium supplementation oral magnesium therapy oral medication oral medications oral methylprednisolone dose oral miconazole oral midazolam oral neomycin oral neomycin sulfate oral nitrates oral oxycodone oral phosphate supplements oral physiological supplementation oral placebo oral retinoids oral route oral self-administration oral solution oral solution one study oral suspension oral tablet oral therapies oral vasodilators oral vitamin oral-dose clearance orally administered antibiotics orally administered anticoagulant agents orally administered methylxanthines orally disintegrating tablet orally ingested peginterferon orally inhaled ciclesonide orange juice orange juices order of application orders of magnitude organ systems organ transplant patients organ transplants organic cation transport organic cationic secretion organic cationic transport system organic cationic transporter systems organic lead organic nitrates organization criteria organophosphorous compound original medication orphan drug status orudis kt osteoporosis treatment osteoporosis treatment study otc dose other agents affecting myelopoesis other antiepileptic drugs phenytoin other drugs aliskiren other drugs aripiprazole other drugs given concurrently other fibrates niacin other potentially significant drug interactions other statins ototoxic effects ototoxic potential ototoxicity of aminoglycoside antibiotics ototoxicity of neomycin otthostatic hypotension outcome of pregnancies outpatient services outward rectification ovarian cancer ovarian follicles ovarian granulosa cell tumors over-the-counter cough over-the-counter medicines overactive thyroid overdosage of drugs overlapping administration overlapping toxicities overload glycemia overt renal failure ovulation prevention oxidase enzyme oxidase enzyme system oxidase inhibition oxidase inhibitor oxidase inhibitory effects oxidase reactions oxidation of mercaptopurine oxidation system oxidative insult oxidative metabolites oxidative stress oxidative stress induction oxide donor compounds oxidized irbesartan metabolites oxolinic acid oxygen species oxytocic agents oxytocic drugs p-aminosalicylic acid p-glycoprotein substrate p-glycoprotein transporter p-glycoprotein-mediated drug clearance p-glycoprotein-mediated transport pacemaker activity package insert of medication package inserts package inserts of medication paclitaxel clearance pain mechanisms pain medication palythoa tuberculosa palytoxin-induced contraction pancreatic acinar cells pancreatic alpha cell pancreatic cancer patients pancreatic content pancreatic effects pancreatic insulin pancreatic insulin release pancreatic supplements panretin gel para-aminobenzoic acid para-aminobenzoic acid metabolite para-aminosalicylic acid paraaminohippurate method paraclinical pattern parallel group parallel group drug interaction study parameter values parameters of ethinylestradiol parametric dose-response models paranoid symptoms parasite reduction parasympathomimetic effects parathyroid function parathyroid-function tests parent compound parent drug parental antihypertensive drugs parenteral anesthetic parenteral antibiotics parenteral route parenterally administered bumetanide pargyline hc pargyline pretreatment parietal cell parietal cell activation parietal cells parkinson's disease parkinsons disease parorchis acanthus partial thromboplastin time partial thromboplastin times partially impaired renal function particular mao inhibitor partners of women parvum growth pass metabolism pass metabolism of nimodipine patch pipette patch-clamp whole-cell recording technique pathogenic species pathogens of drug addicts pathophysiologic abnormality pathophysiologic consequences patient access patient compliance patient data patient demographics patient group patient or guardian patient pharmacokinetic data patient population patient populations patient response patient survival patient's response patient's serum potassium patients liver patients of childbearing potential patients optimal care patients response patients reveiving phenytoin patients serum potassium patients therapy patients thyroid gland pattern of efficacy pattern of magnesium deficit pcp combination procedures pcp discrimination pcp intoxication pcp treatment pcp-induced behavioral pcp-induced behaviors pcp-induced hyperlocomotion peak blood concentration peak cefdinir plasma levels peak concentration peak concentrations peak diltiazem plasma levels peak latency peak levels peak nifedipine plasma levels peak nimodipine plasma concentrations peak plasma concentration peak plasma concentrations peak plasma level peak plasma levels peak serum level peak serum levels pediatric patients pegasys treatment pelvic girdle penicillin-type drug pentobarbital-induced sedation times peptide drugs peptide drugs bacitracin percentage increase percentage of drug percentage of neurons percentage of patients perfused pancreas perhexiline hydrogen maleate period of observation period of organogenesis periodic intervals periodic liver function testing periodic measurement periodic monitoring periodic serum level determinations periods of time perioperative administration perioperative period peripheral adrenergic blocking drugs peripheral blood peripheral blood cell counts peripheral edema peripheral mononuclear cells peripheral neuropathy peripheral opioid anitagonism peripheral vascular resistance peripheral vasoconstriction peripheral vasoconstrictors peripheral wasting peripherally restricted opioid antagonist peritoneal cavity peritoneal metastasis perivascular hemorrhages perivascular spaces permanent nerve damage permeation of sodium fluorescein peroral administration persistent buffering effects persistent inhibition persistent ovarian follicles persistently elevated plasma concentrations personality characteristics pertechnetate tc pesticide gliftor pharmaceutical abstract pharmacist approval pharmaco-dynamic effects pharmacodynamic consequences pharmacodynamic data pharmacodynamic drug-drug interactions pharmacodynamic effect pharmacodynamic effects pharmacodynamic interaction pharmacodynamic interaction asa result pharmacodynamic interactions pharmacodynamic parameters pharmacodynamic profile pharmacodynamic-related interactions pharmacodynamics of coadministration pharmacodynamics of digoxin pharmacodynamics of glyburide pharmacoeconomic analyses pharmacogenetic investigations pharmacogenetics deals pharmacokinetic analyses pharmacokinetic analysis pharmacokinetic basis pharmacokinetic captopril-digoxin interaction pharmacokinetic data pharmacokinetic disposition pharmacokinetic dosing pharmacokinetic drug-drug interaction pharmacokinetic drug-drug interactions pharmacokinetic effects pharmacokinetic evaluation pharmacokinetic interaction study pharmacokinetic parameter values pharmacokinetic profile pharmacokinetic profiles pharmacokinetic screening pharmacokinetic study pharmacokinetic substudy pharmacokinetic variability pharmacokinetic variables pharmacokinetic-based drug-drug interaction pharmacokinetic-pharmacodynamic relationship pharmacokinetic-related interactions pharmacokinetics analysis pharmacokinetics data pharmacokinetics of acamprosate pharmacokinetics of almotriptan pharmacokinetics of antipyrine pharmacokinetics of aripiprazole pharmacokinetics of atorvastatin pharmacokinetics of azithromycin pharmacokinetics of benzodiazepines pharmacokinetics of bupropion pharmacokinetics of butorphanol pharmacokinetics of calcium-entry blockers pharmacokinetics of capecitabine pharmacokinetics of carbamazepine pharmacokinetics of cerivastatin sodium pharmacokinetics of citalopram pharmacokinetics of clonazepam pharmacokinetics of doxorubicin pharmacokinetics of drugs pharmacokinetics of eptifibatide pharmacokinetics of escitalopram pharmacokinetics of estazolam pharmacokinetics of ethanol pharmacokinetics of ethinylestradiol pharmacokinetics of etodolac pharmacokinetics of everolimus pharmacokinetics of felodipine pharmacokinetics of fosfomycin pharmacokinetics of fulvestrant pharmacokinetics of gemifloxacin pharmacokinetics of irbesartan pharmacokinetics of itraconazole pharmacokinetics of levetiracetam pharmacokinetics of methotrexate pharmacokinetics of nelfinavir pharmacokinetics of ondansetron pharmacokinetics of phenytoin pharmacokinetics of praziquantel pharmacokinetics of prednisolone pharmacokinetics of propranolol pharmacokinetics of rofecoxib pharmacokinetics of saquinavir pharmacokinetics of sumatriptan pharmacokinetics of terfenadine pharmacokinetics of theophylline pharmacokinetics of triazolam pharmacokinetics of valproate pharmacokinetics of warfarin pharmacokinetics parameters pharmacokinetics-pharmacodynamics of fondaparinux sodium pharmacokinetits of cerivastatin sodium pharmacologic action pharmacologic activities pharmacologic agents pharmacologic doses pharmacologic effect pharmacologic effects pharmacologic interactions pharmacologic mechanism pharmacological action pharmacological actions pharmacological analysis pharmacological doses pharmacological effect pharmacological effects pharmacological indications pharmacological interaction pharmacological interactions pharmacological magnesium therapy pharmacological properties pharmacological tool pharmacological treatment pharmacological-pharmacodynamic interactions pharmacologically predictable sympathetic effects pharmacology drug interactions pharmacology section pharmacology study pharmacology-pharmacokinetics-drug-drug interactions pharmacology-related endocrine feedback alterations phase extraction phase schizophrenia phasic contraction phenelzine sulfate phenobarbital carbamazepine potential phenobarbital concentration phenobarbital level phenobarbital plasma concentrations phenobarbital sodium phenobarbital sodium-kg phenobarbital toxicity phenobarbital treatment phenobarbital-valproic acid phenolic metabolites phenothiazine derivatives phenothiazine-related compounds phenotypic subset phenylbutazone causes increase phenytoin acts asa stimulator phenytoin administration phenytoin andtolbutamide phenytoin auc phenytoin cmin phenytoin coadministration phenytoin concentrations phenytoin dose phenytoin dose reduction phenytoin indinavir concentration phenytoin intoxication phenytoin keppra phenytoin levels phenytoin metabolism phenytoin monotherapy phenytoin phenobarbital carbamazepine potential phenytoin plasma concentration phenytoin plasma concentrations phenytoin serum level phenytoin serum levels phenytoin sodium phenytoin sodium capsules phenytoin therapy phosphatase activities phosphatase activity phosphate buffer phosphate concentration phosphate formation phosphate supplements phosphate-binding agents phosphatidate phosphohydrolase phosphokinase antibody phospholine iodide phospholipid concentration phosphorylated lamivudine concentration phosphorylated zalcitabine phosphorylated zidovudine phosphorylation of zalcitabine phosphorylation status photic evoked potential components photic evoked potentials photic stimulation photometric methods photosensitivity reaction photosensitizing agents physical activity physical dependency physical exertion physiologic activity physiologic effects physiological doses physiological oral magnesium load physiological oral magnesium supplementation physiological oral magnesium therapy physiological supplementation physiological tolerance physostigmine pretreatment pi indinavir pi nelfinavir pi-based regimens pi-based therapy picrate method pimozide contraindicated piperacillin peak serum level piperacillin sodium piperacillin-tazobactam injection pituitary secretion pituitary-gonadal axis pk properties placebo group placebo treatment placebo-controlled clinical placebo-controlled crossover study placebo-controlled trial placebo-treated patients placental margin placental vessels placental weight plasma albumin plasma alprazolam concentrations plasma area-under-the-curve plasma asparagine levels plasma atovaquone concentrations plasma auc plasma auc values plasma bexarotene concentrations plasma carbamazepine plasma cisapride levels plasma clearance plasma clearance of ketoprofen plasma clonazepam levels plasma concentration data plasma concentration of acetaminophen plasma concentration of alprazolam plasma concentration of bosentan plasma concentration of doxepin plasma concentration of imipramine plasma concentration of methotrexate plasma concentration of terfenadine plasma concentration profile plasma concentration time-curve plasma concentration-time curve plasma concentrations cyp plasma concentrations drugs plasma concentrations of almotriptan plasma concentrations of aprepitant plasma concentrations of astemizole plasma concentrations of atomoxetine plasma concentrations of atorvastatin plasma concentrations of bexarotene plasma concentrations of bosentan plasma concentrations of buprenorphine plasma concentrations of capecitabine plasma concentrations of carbamazepine plasma concentrations of carvedilol plasma concentrations of cimetidine plasma concentrations of ciprofloxacin plasma concentrations of corticosteroids plasma concentrations of cyclosporine plasma concentrations of digoxin plasma concentrations of drugs plasma concentrations of felodipine plasma concentrations of fexofenadine plasma concentrations of flecainide plasma concentrations of glyburide plasma concentrations of imipramine plasma concentrations of indinavir plasma concentrations of itraconazole plasma concentrations of methadone plasma concentrations of midazolam plasma concentrations of oxcarbazepine plasma concentrations of parent drug plasma concentrations of penciclovir plasma concentrations of phenytoin plasma concentrations of procainamide plasma concentrations of quinolone antibiotics plasma concentrations of saquinavir plasma concentrations of simvastatin plasma concentrations of terfenadine plasma concentrations of theophylline plasma concentrations of vitamin plasma concentrations of zaleplon plasma corticosteroid levels plasma cortisol concentration plasma digitoxin concentrations plasma digoxin concentrations plasma digoxin levels plasma disopyramide levels plasma doxazosin plasma drug concentrations plasma drug levels plasma elimination half-life plasma enoxacin levels plasma enzymes plasma expanders plasma exposure plasma exposure of cefditoren plasma exposure of diazepam plasma exposure of valdecoxib plasma exposures plasma felbamate concentrations plasma fibrinogen plasma flecainide levels plasma flow plasma glucose levels plasma half-life plasma half-life of dyphylline plasma half-life of fenoprofen plasma haloperidol levels plasma hdl plasma kinetics plasma level plasma levels of acetaminophen plasma levels of aliskiren plasma levels of amiodarone plasma levels of anticonvulsant agents plasma levels of antidepressant plasma levels of astemizole plasma levels of bosentan plasma levels of calcitriol-ergocalcitriol plasma levels of calcium plasma levels of combination plasma levels of cyclosporine plasma levels of diazepam plasma levels of diflunisal plasma levels of digoxin plasma levels of disopyramide plasma levels of doxorubicin plasma levels of felodipine plasma levels of flecainide plasma levels of hydrochlorothiazide plasma levels of indomethacin plasma levels of methadone plasma levels of methotrexate plasma levels of mhd plasma levels of phenobarbital plasma levels of phenytoin plasma levels of saquinavir plasma levels of theophylline plasma levels of thesemedications plasma levels of thioridazine plasma lipid profile plasma lithium plasma lithium concentration plasma lithium concentrations plasma lithium levels plasma maximum concentration plasma membrane plasma metformin plasma nitrosourea auc plasma of dogs plasma pharmacokinetics plasma phenytoin concentrations plasma protein plasma protein carbamazepine plasma protein eszopiclone plasma protein zaleplon plasma proteins plasma prothrombin activity plasma quinidine concentrations plasma quinidine levels plasma renin activity plasma renin levels plasma samples plasma substrate plasma tca concentrations plasma theophylline concentrations plasma thrombin plasma valproate concentration plasma valproate concentrations plasma warfarin levels plasmacytic hyperplasia plasminogen antigen plate counts platelet activation platelet adhesion platelet aggregability platelet aggregation inhibitors platelet aggregation response platelet aggregation time platelet antiaggregant prostacyclin platelet contents platelet dysfunction platelet effects platelet function tests platelet inhibitors platelet nucleotide release platelet-aggregation reactions platelia aspergillus eia test pneumocystis carinii pneumonia pointer dogs pointes-type ventricular tachycardia polyene antibiotics polymorphic proliferation polystyrene sulfonate pooled human serum population pharmacokinetic population pharmacokinetic analyses population pharmacokinetic analysis population pharmacokinetics analysis porter-silber reaction porter-silber test positive antinuclear phosphokinase antibody positive bivalirudin antibody tests positive coombs test positive direct positive direct coombs test positive direct coombs tests positive inotropic effects positive psychotic symptoms positive readings positive test positive tests positive tricyclic antidepressant level positive urine test positively-charged bile acid sequestrant post myocardial infarction patients post-ganglionic sympathetic nerves post-heparin lipolytic activity post-implantation loss post-marketing experience of coma post-marketing reports post-myocardial infarction postmarketing experience postmarketing observations postmarketing reports postmarketing reports of rhabdomyolysis postmenopausal women subsections postnatal immune function postoperative dose postoperative pain postoperative respiratory depression postsedative treatment control potassium channel potassium chloride potassium kinetics potassium levels potassium-depleted solution potassium-depleting agents potassium-depleting diuretics potassium-sparing antihypertensives potassium-sparing diuretics lotensin potency of norepinephrine potency ration potent diuretics potent effect potent enhancers potent inducers potent inhalational anesthetics potent inhibition potent inhibitors potent inhibitory activity potent loop diuretics potent non-nucleoside reverse transcriptase inhibitor potent parental antihypertensive drugs potential adverse cardiovascular effects potential benefits potential bleeding international normalized ratio potential components potential danger potential decrease potential differences potential drug interaction potential drug interactions potential drug interactions dofetilide potential drug-drug interaction potential effect potential effects potential hazard potential hepatotoxic drugs potential inhibitor potential interaction potential interactions potential nephrotoxicity potential of aminoglycoside antibiotics potential of ciclesonide potential of gabapentin potential of nephrotoxicity potential of ribavirin potential overlapping toxicities potential pharmacokinetic interactions potential risk potential terfenadine potential theophylline toxicity potential treatment potential twofold increase potentially clinically significant drug potentially fatal prolongation potentially favorable effects potentially important drug interactions potentially important effects potentially nephrotoxic drugs potentially serious adverse effects potentially serious cardiovascular adverse effects potentially significant drug interactions potentially toxic drug potentiating action potentiating effects potentiation effects potentiation of ampicillin rashes potentiation of bradycardia potentiation of coumarin-type anticoagulants potentiation of warfarin-type powder x-ray diffraction pr interval pravastatin auc pre-gentamycin strength pre-sacral vertebrae preanesthetic drugs preceding effect preceding lists precipitating factor precipitation of oxypurines precipitation procedure precipitous reduction preclinical researchers predictable sympathetic effects predicted interactions predisposed mice prednisolone sodium succinate prednisone chemotherapy predominant plasma substrate predominant sterol prefrontal cortical tissues pregnancy estrogens pregnancy outcomes pregnancy pregnancy pregnancy rates pregnancy registry pregnancy test pregnancy test female patients pregnancy tests pregnanediol excretion pregnant mice pregnant rhesus monkeys pregnant women preliminary animal preliminary clinical data preliminary investigations preliminary whole-cell premature atherosclerotic cardiovascular disease premature ventricular arrhythmias premenopausal women prescribing apomorphine prescription dose prescription drug coverage prescription of lithium carbonate prescription of thiabendazole presence of agents presence of allopurinol presence of atovaquone presence of azathioprine presence of carbamazepine presence of cimetidine presence of diclofenac presence of dipyridamole presence of drugs presence of food presence of galangin presence of glucose presence of halothane presence of insulin presence of labetalol metabolites presence of morphine presence of nevirapine presence of nitrofurantoin presence of ouabain presence of phentolamine presence of piperacillin presence of probenecid presence of theophylline presence of urine protein preservation of transplants pressor activity pressor agent pressor agents pressor amines pressor drugs pressor effect pressor effects pressor response pressure control pressure effect pressure medications pressure reaction pressure reductions pressure response presumptive q-type presynaptic defect preterm neonates pretreatment of megakaryocytes pretreatment of rats pretreatment period prevent bleeding complications previously administered agents previously administered botulinumtoxin previously effective clozapine dose previously stable plasma levels previously unrecognized interaction primary cns effect primary cns effects primate gammaherpes virus primidone concentrations principal drugs principal pathway principles of recovery prior administration prior ingestion proarrhythmic effect probability distribution probable benefits probe study probenecid increases probenecid prolonged action procainamide doses processing functions prochlorperazine edisylate prodrug form producing medications product interactions production of beta-endorphin production of catecholamines production of hypotension production of tail-flick inhibition profile evaluation profile of digoxin profile of esomeprazole profile of etodolac profile of mood states profiles of norethindrone progestational contraceptives progesterone levels progesterone preparations progesterone serum levels progestin minipill preparations progestin preparations progestin-containing minipill preparations progestin-only oral contraception progestin-only oral contraceptives progestin-only pills progestogen administration prolactin secretion proleukin treatment proleukin-induced side effects proliferation of prostate epithelium prolongation concomitant treatment prolongation of plasma half-life prolongation of prothrombin time prolonged action prolonged administration prolonged cephalosporin blood levels prolonged concurrent prolonged daily administration prolonged diarrhea prolonged gastrointestinal transit time prolonged hot weather prolonged hypertension prolonged hypotension prolonged infusion prolonged menstrual cycles prolonged narcotics prolonged period prolonged prothrombin time prolonged prothrombin times prolonged qt intervals prolonged recovery time prolonged sodation prolonged survival prolonged therapy prolonged thrombocytopenia prolonged vasospastic reactions promoter activity promoter-vana antisense gene cassette promotion of liver damage pronounced effect pronounced inhibition pronounced intersubject variability pronounced secretory diarrhea proper interpretation proper interval proper monitoring properties of anagrelide properties of carbamazepine properties of digoxin properties of magnesium property of acetaminophen property of epinephrine prophylactic doses prophylactic low dose heparin prophylaxis of manic-depressive disorder proportionate responses propoxyphene hydrochloride propoxyphene overdosage propranolol absorption propranolol dose propranolol increases hydralazines serum concentrations propranolol levels propranolols hypotensive effect proprietary cold remedies proquin xr prospective clinical trials prospective study prostaglandin inhibition prostaglandin synthase prostaglandin synthesis-inhibiting drugs prostaglandin synthetase inhibitor prostaglandin synthetase inhibitors prostate cancer prostate epithelium prostate-specific antigen prostatic epithelium prostatic hyperplasia prostin vr pediatric protease inhibitor protease inhibitor therapy protease inhibitors indinavir protein binding of fosphenytoin protein bound protein bound drugs protein carbamazepine protein condensation protein eszopiclone protein reorganization protein tyrosine phosphorylation protein zaleplon protein-binding displacement protein-binding sites protein-bound anafranil protein-bound drugs proteus rettgeri prothrom-bin time response prothrombin activity prothrombin complex concentrates prothrombin determinations prothrombin effect prothrombin level prothrombin levels prothrombin measures prothrombin response prothrombin test prothrombin test monitoring prothrombin time determinations prothrombin time ratio prothrombin time response prothrombin time responses prothrombin time-inr prothrombin time-inr determinations prothrombin-proconvertin concentrations proton pump inhibitors prudent evaluation prudent medical practice psa levels pseudomonas aeruginosa pseudomonas aeruginosa serotype pseudomonas strains pseudotumor cerebri psoriatic arthritis psychiatric disorder psychiatric patients psychiatric rating scale psychoactive drugs psychoactive medications psychopathology rating scales psychopathology symptoms psychostimulant effects psychostimulant self-administration psychotic disorders psychotic patients psychotic reaction psychotic symptoms psychotomimetic effects psychotropic agents psychotropic drug psychotropic drugs ptx-induced release published accounts published information published reports pulmonary arterial hypertension pulmonary disease pulmonary emboli pulmonary embolism pulmonary function pulmonary granulomata pulmonary surfactant extract pulmonary symptomatology pulmonary toxicity pulmonary wedge pressure pulsatile choroidal blood flow pulsation amplitude pulse of carcinogen puncture sites pupil constriction pupil size pupillary dilation pure agonist opioid analgesic pure powders purification protocol pyknotic nuclei pyrazolone derivatives qrs complex qt-interval prolongation qt-qtc interval qt-qtc interval caution qt-qtc interval prolongation qtc increase qtc interval prolongation qtc intervals qtc prolongation qtc values qtc-prolonging drugs qualitative differences quantitative approach quantities of grapefruit juice quetiapine fumarate quetiapine pharmacokinetics quinidine antiarrhythmic agents concentration caution quinidine antihistamines quinidine concentrations quinidine increases quinidine serum concentration quinidine levels quinidine salts quinidine serum concentration quinolone anti-infectives quinolone antibiotics quinolone antimicrobial quinolone class quinolone class antimicrobial quinolone concentrations quinolone package insert quinolones form chelates rabbit erythrocyte haemagglutination assay rabbit kidney cell cultures rabbit kidney slices racemic citalopram racemic warfarin racemic zopiclone exposure rachitic chicks radiation treatment radical-mediated tissue damage radio-iodine uptake radioactive derivative radioenzymatic assay radiographic iodinated contrast media radiolabeled ions radioligand binding experiments radiometric method random observations random sample randomized crossover rantidine hydrochloride rapamycin inhibitor raptiva treatment rare cases rare defect rare occasions rare postmarketing reports rat bone marrow megakaryocytes rat brain rat kidney homogenates rat liver rat megakaryocytes rat milk rat model rat spinal substantia gelatinosa neurons rat thoracic aorta rate increase rate of dissolution rate of dizziness rate of elimination rate of excretion rate of flecainide elimination rate of metabolism rate of salicylate rate requirement rate requirements rate-decreasing effects rate-decreasing effects of morphine rate-limiting step rates of elimination rates of patients rating scale rating scales ratio drugs rats diet rauwolfia alkaloid rbc group rbc mice reaction profile of sirolimus reaction time reactions of paclitaxel reactive encephalopathy reactive oxygen species reactive substances read circulars reagent tablets rearrangements of genomes rebound hypertension rebound phenomena recalcitrant nodular acne recall reaction receiving anticholinergic drugs receiving baclofen tablets receptor agonist receptor antagonism receptor blockers receptor level receptor sensitivity receptor-binding activity receptor-binding activity of toxin receptor-positive subpopulation reciprocal interactions recognition of drug toxicity recombinant shuttle vectors recommended dosage recommended dosages recommended dose ranges recommended doses recommended human dose recommended maximum cumulative doses recommended maximum human therapeutic dose recommended weekly human dose recording pipette recording technique recovering cocaine abusers recovery of hoof twitch recovery programs recovery therapy recovery time recurrence of skin reactions recurrent hypertension red blood cells red cells red clover reddish color reddish stools redistribution-accumulation of body reduced alcohol tolerance reduced amiodarone levels reduced busulfan clearance reduced clearance reduced efavirenz concentrations reduced efficacy reduced infusion rates reduced insulin requirements reduced levels reduced ligand binding activity reduced plasma concentrations reduced protein reduced renal clearance reduced response reduced serum folate concentration reduced statin efficacy reductase inhibitor reductase inhibitor class reduction of anastrozole plasma levels reduction of calcium excretion reduction of growth reduction of letrozole plasma levels reduction of norepinephrine uptake sites reduction of rifabutin reduction tests reevaluations of dosages reflex response reflex tachycardia reformed microtubules refractory epilepsy regimen efficacy regimen mayuse rifabutin regimen of patients regimens of ibandronate regional perfusion regranex gel regression analyses regression model regression models regular intervals regular monitoring regular reevaluations regular users regulation of bloodpressure regulation of topoisomerases regulation of tyrosine phosphorylation rejection episodes relative absorption relative avidities relative bioavailability relative risk relaxant antagonists relaxant drugs relaxant effect relaxant effects relaxants birth control pills release capsules release captopril's effect release formulation release formulation of felodipine release nisoldipine release of duloxetine release of mesalamine release of neutrophils release of platelet contents release tablets reliable affinity chromatography procedure reliable increases reliable method relief of breakthrough symptoms remaining cases remnant removal renal blood flow renal calculi renal calculus formation renal cancer renal cationic secretion renal clearance measurements renal clearance mechanisms renal clearances renal damage renal dialysis renal disease renal disease states renal dysfunction renal effects renal elimination renal excretion ibuprofen renal excretory sites renal impairment renal lithium clearance renal plasma flow renal precipitation renal prostacyclin renal prostaglandins renal retention renal secretion renal therapy regimens renal toxicity renal transplant patients renal transplant recipients renal tubular excretion renal tubular transport renal tubule renal uptake renal vascular renal vasodilator effects renally impaired hypertensive patients renin activity renin hypertension renin levels renin profile evaluation renin release renin release captopril's effect renin-angiotensin system renin-angiotensin-aldosterone system repealed diazepam administration repeat dose pharmacokinetics repeat dose pharmacokinetics of theophylline repeat doses repeat testing repeated co-administration repeated cocaine exposure repeated courses repeated doses repeated injection repellent products reported activity reported association reported dose reported examples reported interactions reported musculoskeletal adverse events reporter gene reports of deaths reports of drug interaction reports of drug interactions reports of increases reports of interactions reports of myopathy-rhabdomyolysis reports of patients reports of pregnancy reports of prolongation reports of rhabdomyolysis reports of sedation reports of serotonin syndrome representative drugs reproducible pattern reproductive hormone status reproductive toxicology reproductive tract infections research centre inventory resemblance of itraconazole reservoir function residual effects residual solvent resistance arteries resistance reversal resistant clinical isolates resistant pathogens resistant strains respectto safety respiratory exchange respiratory failure respiratory recordings response duration response of cancer response rates responses of megakaryocytes resting membrane potential restricted opioid antagonist restricted pulmonary resultant clinical toxicity resultant tumors resulting increase resulting mixture resulting respiratory depression resveratrol activity resveratrol-induced vasorelaxation retention of cobalt retinal tamponades retinogeniculate fibers retinoid therapy retinyl acetate reuptake inhibitor reuptake inhibitor drug reuptake of norepinephrine reveiving phenytoin reverse epinephrine effect reverse transcriptase inhibitor reverse transcriptase inhibitors reverse transcriptase inhibitors didanosine reverse triiodothyronine levels reversible acute renal failure reversible enhancement reversible increases reversible reduction review papers rhesus monkeys rheumatic disease rheumatoid arthritis patients rho family ribavirin distribution ribavirin ribavirin rifabutin concentration rifabutin dose rifabutin indinavir concentration rifabutin rifabutin plasma rifabutin rifabutin rifabutin rifabutin concentration rifabutin toxicity rifampicin therapy rifampin benzodiazepines midazolam rifampin coadministration rifampin contraindicated rifampin efavirenz concentration clinical significance rifampin nevirapine rifampin pharmacokinetics rifampin therapy rifampin withdrawal righting reflex rising degree risk factors risk of agranulocytosis risk of arrhythmias risk of cardiotoxicity risk of corticosteroid side effects risk of dehydration risk of depression risk of drug toxicity risk of habituation risk of heart problems risk of hemorrhage risk of hypervitaminosis risk of hypoglycemia risk of methaemoglobinaemia risk of methotrexate risk of myopathy-rhabdomyolysis risk of nephrotoxicity risk of neuropathy risk of neutropenia risk of rashes risk of salicylate toxicity risk of toxicity riskfor rifabutin toxicity risks of bleeding risperidone treatment ritonavir concentration combination ritonavir indinavir concentration ritonavir ritonavir label ritonavir plasma ritonavir ritonavir concentration combination rna effect robinul injection robust induction rocuronium administration rodent pups rodent study denileukin diftitox roegnik grade roegnik grade iiia rofecoxib plasma concentrations rofecoxib treatments role of antihistaminics role of norepinephrine role of paroxetine role of valdecoxib route of elimination route of metabolism routine administration routine diagnostic tests routine dosage adjustment routine monitoring rural health rural primary care centre ruthenium red safe dosing regimens safe problem safe sexual activity safety concern safety of cisapride safety profile of desloratadine safety profile of loratadine safety profiles salicylate assays salicylate dosage salicylate levels salicylate renal excretion salicylate serum levels salicylate therapy salicylate toxicity salicylic acid saline administration saline values saline vehicle saline-treated controls salivary cortisol salivary cortisol levels salmonella typhimurium salt restriction sans fronti res saquinavir appropriate doses saquinavir concentration saquinavir hard gelatin capsules saquinavir plasma saquinavir plasma concentrations saquinavir saquinavir appropriate doses saquinavir saquinavir concentration saquinavir steady-state cmax saquinavir-ritonavir combination satisfactory hypotensive effect satisfactory therapeutic effect satisfactory therapeutic hypoprothrombinemia saturable metabolism sc injections scanning calorimetry schedule of cerivastatin sodium schedule of food presentation schistosoma mansoni schistosoma mansoni miracidia schizoaffective disorder schizophrenia symptoms schizophrenic patients sclerosis patients screening patients screening test screening urine seal recordings seal recordings of rat secobarbitone sodium second hour secretion of ampicillin secretion of bumetanide secretion of cardiotrast secretion of cephalosporins secretion of ciprofloxacin secretion of immunoglobulins secretion of nitrofurantoin secretion of ucb secretion of zalcitabine secretory diarrhea secretory diarrhea model secretory effect secretory iga sedating drugs sedation time sedation times sedative effect sedative effects sedative side effects see clinical pharmacology see tables see warnings seemingly adequate treatment seizure control seizure risk seizure threshold selection of drugs selective ca selective cyp selective inhibitors selective mao inhibitor selegiline selective marker substrates selective methods selective opioid agonists selective peripheral opioid anitagonism selective regulation selective serotonin reuptake inhibitor selective survival selective toxicity selective tumour cell selegiline hydrochloride self-administration of benzodiazepines self-administration of ethanol self-administration of morphine self-reported mood seminiferous tubular atrophy seminiferous tubules sensitive assay system sensitive cyp sensitivity of rat sensitivity of tumour separate brain systems separate controlled separate days separate group separate information separate randomized crossover separate section separate single separate study septic shock sequential high dose proleukin sequential infusions sequential study sequential trials serial broth dilution method serial measurement serial pharmacokinetic serial pharmacokinetic dosing serial plasma serious gi seropositive subjects serosal surfaces serosal transport serotonergic agents serotonergic effects serotonin release serotonin releaser serotonin reuptake serotonin reuptake inhibitor serotonin reuptake inhibitor drug serotonin syndrome serotoninergic agents serotoninergic central pathways sertraline concentration increases sertraline dose sertraline sertraline concentration increases serum albumin serum amiodarone levels serum amprenavir auc serum amylase serum amylase activity serum amylase levels serum androgen concentrations serum androgen concentrations of estradiol serum bilirubin levels serum calcium concentrations serum calcium levels serum calcium measurements serum clearance serum concentration serum concentration curve serum concentration of digoxin serum concentration of phenytoin serum concentration of selegiline serum concentrations of amiodarone serum concentrations of amprenavir serum concentrations of digoxin serum concentrations of disopyramide serum concentrations of drugs serum concentrations of glucose serum concentrations of isoniazid serum concentrations of levetiracetam serum concentrations of penicillins serum concentrations of primidone serum concentrations of theophylline serum constituent serum creatinine serum creatinine concentration serum creatinine level serum creatinine levels serum cyclosporin level serum deprivation serum digitalis levels serum digoxin serum digoxin concentration serum digoxin concentrations serum digoxin level serum digoxin levels serum electrolytes serum enzyme activities serum enzymes serum estrogen concentrations serum estrogen concentrations of estradiol serum exposure serum flurbiprofen concentrations serum flurbiprofen time profiles serum folate concentration serum half-life serum half-life of phenytoin serum haloperidol concentrations serum infliximab concentrations serum iron serum level serum level determinations serum levels carbamazepine serum levels of carbamazepine serum levels of cyclosporine serum levels of digoxin serum levels of exposure serum levels of methotrexate serum levels of oxyphenbutazone serum levels of phenytoin serum levels of theophylline serum lithium concentration serum lithium concentrations serum lithium levels serum magnesium serum magnesium levels serum phenytoin levels serum phosphate concentration serum plasma proteins serum potassium levels serum pregnancy test serum pregnancy tests serum prostate-specific antigen serum protein serum protein-bound iodine serum proteins serum psa serum psa levels serum salicylate serum salicylate assays serum salicylate levels serum samples serum sex steroid hormone response serum steroid hormone levels serum tests serum theophylline concentrations serum theophylline levels serum thyroxine-binding globulin serum total bilirubin serum total testosterone concentrations serum transaminase levels serum tricyclic antidepressant levels serum triglyceride serum uric acid level serum uric acid levels serum valproic acid concentrations serum-deprived ras-transformed seven cases seven cerebrovascular accidents seven experiments reactions seven healthy volunteers seventeen percent severe abdominal symptoms severe acetaminophen toxicity severe adverse drug reaction severe allergic reactions severe anemia severe autonomic neurotoxicity severe bradycardia severe bronchospasm severe cardiovascular disease severe dietary salt restriction severe drymouth severe enterocolitis severe events severe high bloodpressure reaction severe hyperkalemia severe hypersensitivity reactions severe hypertension severe hypocalcemia severe hypotension severe leukopenia severe malaria severe muscle weakness severe myelosuppression severe myopathy severe neutropenia severe obstipation severe orthostatic hypotension severe pulmonary toxicity severe reaction severe reactions severe recalcitrant nodular acne severe renal failure severe rhabdomyolysis severe sepsis severe short bowel syndrome severe structural heart disease severe symptomatology severe toxicity severe weakness severe withdrawal symptoms severely impaired renal function severity of diarrhea severity of potassium severity of side effects sex hormone-binding globulin sex steroid hormone response sex steroids sexual activity sexual dysfunction sexual intercourse sg dipstick test sh-bearing molecules sharp fall short bowel syndrome short sedation time short-acting adrenergic stimulant type short-acting benzodiazepines short-acting drug short-acting nitrates short-term controlled short-term controlled study short-term pharmacokinetic short-term treatment shortened elimination half-life should be reduced should be used with caution shuttle vectors sickle cell disease sickness centre sickness medications side chains side effects of azithromycin side effects of methotrexate side effects of succinylcholine side reactions side-effect profiles side-effects of opioids sideeffect of phenytoin sideeffect profile sideeffect profile of diltiazem sign monitoring signal function signalled-unsignalled differential-reinforcement-of-low-rates significance unknown significant drug significant drug interactions significant qtc prolongation significantly affected prothrombin times significantly fewer extrapyramidal symptoms significantly higher proportion significantly increased plasma levels significantly increased vasoconstriction significantly longer latencies significantly lowered numbers significantly smaller proportion signs of atropinization signs of hypoglycemia signs of hypotension signs of lithium toxicity signs of sedation signs of toxicity signs of withdrawal sildenafil citrate sildenafil concentration sildenafil sildenafil concentration sildenafil therapy silver preparations similar serum flurbiprofen time profiles simulect clearance values simultaneous administration simultaneous dosing simultaneous ingestion simultaneous reduction simultaneous treatment simvastatin metabolism simvastatin therapy simvastatin warning potential sinequan overdosage single administration single agent single case single compound single daily oral dose single dosage single dose administration single dose bioavailability single dose pharmacokinetics single dose study single doses single enzyme single high dose single hypnotic dose single intravenous infusion single metal toxicity single metals single method single oral dose single oral doses single pancreatic acinar cells single study single subject single submaximal doses single tonic convulsion single weekly methotrexate doses single-dose administration single-dose crossover study single-dose diltiazem coadministration single-dose interaction study single-dose nature single-dose pharmacokinetic study single-dose study sinus arrest sinus bradycardia sinus medicines sinus node function sinus rhythm sirolimus area sirolimus concentrations sirolimus exposure sirolimus-diltiazem interaction site of absorption site reaction site reactions situ hybridization six cases six clinical isolates six healthy volunteers six hours six months six patients six subjects six sudden cardiac deaths six typical case reports six volunteers six-healthy-male volunteers sizeof wheal skeletal muscle skeletal myopathy skeletal-muscle relaxants skin discoloration skin exfoliation skin medicines skin products skin rash skin reactions skin tests skin wheals slaughter technique sleep time sleeping sickness centre sleeping time slight decrease slight decreases slight degree slight delay slight effects slight increases slight intrinsic anticonvulsant effect slight reduction slow alterations slow amphetamine metabolism slow av conduction slow chylomicron intravascular catabolism slow metabolizers slow phasic contraction slow-channel calcium blockers small gtp-binding proteins smaller alfenta doses smoking cessation socioeconomic factors sodium absorption sodium acid phosphate sodium bicarbonate sodium capsules sodium carboxymethylcellulose sodium cephalothin sodium channels sodium citrate sodium colistemethate sodium colistimethate sodium dodecyl sulfate sodium excretion sodium fluorescein sodium injection sodium iodide sodium levels sodium nitroprusside sodium overdosage sodium perchlorate sodium pertechnetate tc sodium plasma levels sodium plasma valproate concentrations sodium polystyrene sulfonate sodium succinate sodium thiosulfate sodium thiosulfate protection sodium under-dosage sodium valproate soft-gelatin capsule formulation soft-gelatin capsule formulation of saquinavir sole indication sole method sole protease inhibitor solubility of dasatinib soluble magnesium solution of dextrose solution of ethanol solution one study somatic disease states somatostatin analogs somatostatin analogue soriatane therapy soybean flour sparing diuretics spatial discrimination task species of bacteria spectrometer technique spectrophotometrically determined urinary laboratory tests spectrum of actions spectrum of activity spinal cord injuries spinal endorphinergic system spinal naloxone-sensitive endorphinergic system spinal substantia gelatinosa neurons spontaneous action potentials spontaneous motility spontaneous term delivery sporadic cases sprague-dawley rats sprycel dose reduction sprycel plasma concentrations sprycel therapy squares approach squirrel monkeys ssri-associated sexual dysfunction ssri-tca interactions sst mice st johns wort stability of nucleophosmin-b stable a-strain subjects stable angina stable angina pectoris stable dosage stable doses stable exposure stable hepatic disease stable plasma levels stable prothrombin time stable simvastatin therapy stable warfarin therapy stadol ns standard clinical laboratory tests standard clinical practice standard cystic fibrosis therapies standard dose standard heparin standard monitoring standing systolic bloodpressure staphylococcus aureus starlix three times start of treatment state plasma concentrations states of disease statin dose statin efficacy statistical analysis statistical work statistically significant decrease statistically significant difference statistically significant differences statistically significant effect steady partner steady-state auc steady-state auc of ciprofloxacin steady-state auc of didanosine steady-state blood concentrations steady-state blood concentrations of lomefloxacin steady-state blood levels steady-state bosentan plasma concentrations steady-state carbamazepine epoxide plasma concentration steady-state carbamazepine plasma concentrations steady-state cerivastatin auc steady-state cmax steady-state cmin steady-state cmin concentration steady-state cmin concentrations steady-state concentrations steady-state fexofenadine pharmacokinetics steady-state levels steady-state levels of quinidine steady-state lithium plasma levels steady-state maximum concentration steady-state pharmacokinetic variables steady-state pharmacokinetics steady-state pharmacokinetics of digoxin steady-state pharmacokinetics of everolimus steady-state pharmacokinetics of quetiapine steady-state phenytoin cmin steady-state phenytoin plasma concentrations steady-state plasma atovaquone concentrations steady-state plasma concentration steady-state plasma concentration of theophylline steady-state plasma concentrations steady-state plasma concentrations of aeds steady-state plasma concentrations of carbamazepine steady-state plasma concentrations of phenytoin steady-state plasma digoxin concentrations steady-state plasma felbamate concentrations steady-state serum concentrations steady-state serum digoxin concentrations steady-state serum tricyclic antidepressant levels steady-state theophylline peak serum levels steady-state trough steady-state trough concentrations steady-state trough plasma carbamazepine steady-state trough plasma concentrations steady-state valproate concentrations steadystate conditions steadystate level steadystate levels steadystate plasma concentrations steadystate plasma digitoxin concentrations steadystate plasma exposure steadystate plasma lithium concentrations steadystate plasma lithium levels steadystate serum levels steadystate trough steadystate valproate cmin steps physicians stereoselective behavioral effects stereotyped behaviour stereotypic effects steroid dependent hypertension steroid determinations steroid dosage steroid hormone levels steroid hormone response steroid hormones steroid inhaler steroid medicine steroid production steroid toxicity steroid withdrawal steroidal anti-inflammatory agent steroidal anti-inflammatory agents steroidal antiinflammatory agent steroidal estrogen stevens-johnson syndrome stimulant action stimulant effects stimulant effects of amphetamines stimulant type stimulated gastric secretion stimulating effect stimulating properties stimulatory effects stimulus response stimulus-induced neural plasticity stock solution stomach acidity stomach irritation stomach of people storage vesicles strain of dogs strains combinations strains of enterococcus strains of pointer dogs strenuous physical activity streptococcus pyogenes streptozotocin-induced diabetic rats stress induction stress test striatal dopamine striatal dopamine concentrations strip usp stroke trial strong affinity strong central nervous system depressants strong drying effect strong inducers strong inhibitor strong inhibitors strong likelihood strong seasonal variation strong selective cyp strong synergistic activity structural alterations structural heart disease structural similarity structure of contortrostatin studies drug name effect studies involving alprazolam studies that toradol study data study denileukin diftitox study entry study objective study periods sub-therapeutic concentrations subacute hepatitis subcortical structures subcutaneous dose subcutaneous infusion pumps subcutaneous injections subfraction concentrations subjective effects subjective responses subjects discontinued therapy sublingual nitrates sublingual nitroglycerin submaximal doses subnormal insulin release subnormal pancreatic insulin release subsequent adjustment subsequent bleeding subsequent courses subsequent cycles subsequent diagnostic serum tests subsequent recovery subsequent synthesis subsequent treatment substantia gelatinosa neurons substantial accumulation substantial inactivation substantial increases substantial interaction substantial intercurrent ethanol substantial number substantial period substantially greater therapeutic index substantive effect substitution test substrate cisapride substrate drug substrate hypnotic agent substrate theophylline substrate triazolam substrates-inhibitors sulphenazole subutex tablets succinylcholine chloride succinylcholine-induced neuromuscular block succinylcholine-induced neuromuscular blockade such as narcotics sudden cardiac deaths sudden death sudden extrusion sudden increase sudden steroid withdrawal sudden withdrawal sufficient data sufficient function sufficient numbers sugar concentrations sugar control sugar level suitable anticoagulation test suitable coagulation test suitable coagulation tests sular tablets sulfa medicines sulfa-based drug sulfacetamide preparations sulfate neuromuscular blocking effects sulfate tests sulfide metabolite sulfobromophthalein retention sulfonamide antibiotics sulfonamide drug sulfonylurea agent sulfonylurea glyburide sulfosalicylic acid precipitation procedure sulfoxide concentrations sulfoxide plasma concentrations sulindac sulfide metabolite sulphydryl-containing amino acid sum of desethylzaleplon sumatriptan nasal spray sumatriptan succinate superimposed concentration-responses curves superior antipsychotic efficacy superiority of efavirenz supine position supine systolic-diastolic bloodpressure reductions supplement st supplemental folic acid supplemental l-glutamine supplemental oxygen supplementary cobalt supplementary iron supplementary oral cobalt supplements-antacids products supplied aerolizertm inhalation device suppression of glucagon suppression of glucagon release suppression of midcycle gonadotropin peaks suppression of organs suppression test suppression warrants consideration suppressive effect supraspinal brain sites supraventricular arrhythmia supraventricular arrhythmias supraventricular tachycardia surface area basis surface histidine residues surface of magnesium trisilicate surfactant extract surgical procedures survival of miracidia susceptible patients susceptible pediatric patients suspect compounds sustained elevation sustained-release calcium channel blockers sustained-release nifedipine sustained-release tablets sustained-release verapamil sustiva antihistamines sustiva drug class drugs sustivab anticoagulants symbol copying test symbol substitution test sympathetic activity sympathetic effects sympathetic nerves sympathetic nervous system sympathetic reflex response sympatholytic medicinal products sympathomimetic agents sympathomimetic amine sympathomimetic bronchodilators sympathomimetic drugs symptom control symptom onset symptomatic hyperlactatemia-lactic acidosis symptomatic hypotension symptomatic orthostatic hypotension symptomatic therapy symptoms of aggression symptoms of anticholinesterase overdose symptoms of carbamazepine toxicity symptoms of drug inter-action symptoms of hyperglycemia symptoms of hyperlipidemia symptoms of hypoglycemia symptoms of lithium toxicity symptoms of serotonin syndrome symptoms of vitamin synaptic concentration synergistic activity synergistic anticonvulsant action synergistic antidepressant activity synergistic depressant effects synergistic effect synergistic elevation synergistic relationship synthesis-inhibiting drugs synthetase inhibitor synthetase inhibitors synthetic alkyl esters synthetic analogue d-ala synthetic estrogens synthetic galloyl esters synthetic hydroalcoholic solutions synthetic oxytocin synthetic steroidal estrogen synthetic steroids system depressant system depressant effects system depressants such as narcotics system depression system development system fentanyl system function system penetration system stimulants systematic experience systemic administration systemic anti-ks agents systemic antibiotic agents systemic anticholinesterase treatment systemic antimicrobial agents systemic antiretroviral agents systemic beta-blockade systemic blood flow systemic clearance systemic clonidine systemic concentrations systemic corticosteroids systemic cyclosporine systemic data systemic dofetilide exposure systemic levels systemic levobupivacaine levels systemic medications systemic steroids systemic vascular resistance systemically administered leucovorin systems lapatinib systolic bloodpressure systolic-diastolic bloodpressure reductions t-pa stroke trial tablet formulation tablet of digoxin tablet volume tablets simultaneous administration tablets usp tacrolimus blood concentration tacrolimus blood concentrations tacrolimus dosage tacrolimus dosage adjustments tacrolimus dose tacrolimus felodipine tadalafil concentration tadalafil tadalafil concentration tail-flick inhibition tail-flick response tail-flick test tannic acid tarceva dose tardive dyskinesia side reactions target cell target drug target drug-added drug combinations target of rapamycin inhibitor target sites target tissues targretin capsules tarsal flexure taste disorder taxol infusion taxol infusions taxol safety taxol therapy tbars levels tbg concentration tbg concentrations tbg deficiency tc suspension tca concentrations tca plasma levels tca treatment tea gallocatechins tea polyphenols techniques confirmation template bleeding time temporal patterns temporary decrease ten days tendon reflexes tenofovir disoproxil fumarate teratogenic effect teratogenic effects terfenadine antimigraine terfenadine levels terfenadine metabolite terfenadine therapy term delivery term therapy terminal half-life terminal half-life of aprepitant terms of pregnancy rates terms of safety terms sildenafil test abnormalities test agent test alterations test drug test female patients test findings asymptomatic test interaction test interaction captopril test interaction fosinopril test interactions acetaminophen test interactions amerge tablets test interactions asa result test interactions bisphosphonates test interactions blood glucose test interactions cephalosporins test interactions certain endocrine test interactions corticosteroids test interactions effect test interactions false elevations test interactions finasteride test interactions frova test interactions increases test interactions mylotarg test interactions naproxen test interactions phenytoin test interactions see clinical pharmacology test interactions serum salicylate assays test interferences test metals test monitoring test period test sample test strip usp test strips testicular atrophy testicular leydig cell tumors testing of newborns testosterone concentrations tests interactions tests interactions hyperaminotransferasemia tests of radio-iodine uptake tests pregnancy test female patients tests response tetracyclic antidepressants tetracycline class th day of treatment that the prothrombin time-inr that toradol the prothrombin time-inr thedosage of indinavir thedosage of saquinavir their absorption theobromine grepafloxacin theophylline auc theophylline clearance theophylline concentrations theophylline dosage theophylline doses theophylline levels theophylline maintenance dose theophylline metabolism theophylline peak serum levels theophylline plasma concentration theophylline plasma concentrations theophylline plasma levels theophylline serum levels theophylline therapy theophylline toxicity theophylline vioxx theophylline-induced anxiogenic effects theophylline-quinolone therapy theophylline-related adverse effects theophylline-related adverse reactions theophylline-related side effects theophylline-related side-effects theoretical basis theoretical potential theoretical risk therapeutic action therapeutic actions therapeutic advantage therapeutic agents therapeutic benefit therapeutic blood levels therapeutic concentration monitoring therapeutic concentrations therapeutic digoxin levels therapeutic dosages therapeutic dose therapeutic dose range therapeutic doses therapeutic drug monitoring therapeutic drugs therapeutic effect therapeutic effects therapeutic efficacy therapeutic hypermagnesaemia therapeutic hypoprothrombinemia therapeutic index digoxin therapeutic indices therapeutic interval therapeutic iron supplement therapeutic levels therapeutic margin therapeutic monitoring therapeutic monoclonal antibodies therapeutic point therapeutic ratio therapeutic ratio drugs therapeutic regimen therapeutic regimes therapeutic response therapeutic superiority therapeutic update therapeutic value therapeutic window therapeutic windows theraputic agents therapy compliance therapy interruption therapy regimens therapy standard therapy urinary excretion therefore smaller alfenta doses thermal analysis these two drugs can lead thiazide diuretic thiazide diuretic therapy thiazide drugs thiazide-type diuretics thienobenzodiazepine derivative thin-layer chromatographic assay thio compounds thiobarbituric acid reactive substances thioether assay thioether assay asa method thioether concentration ranges thioether excretion thioether products thiolated carboxymethylcellulose thiosulfate infusion thiosulfate protection third hour thoracic aorta those patients reveiving phenytoin three duloxetine-treated patients threohydrobupropion metabolite threohydrobupropion metabolite of bupropion threshold limit threshold voltage-dependent ca thrombin time thrombocyte function thromboembolic disorders thrombolytic agents thromboplastin time thromboplastin times thrombus formation thyroid administration thyroid binding globulin thyroid dose thyroid drugs thyroid function thyroid gland thyroid hormonal replacement thyroid hormone activity thyroid hormone levels thyroid hormone replacement therapy thyroid hormone synthesis thyroid hormone therapy thyroid hormones thyroid medication thyroid physiology thyroid preparation thyroid preparations thyroid replacement therapy thyroid requirements thyroid status thyroid-stimulating hormone thyroidal uptake thyroxine output thyroxine preparations thyroxine-binding globulin thyroxine-binding prealbumin tiagabine clearance tiagabine concentration tiagabine multiple-dose regimens tiagabine pharmacokinetics time determinations time points time profiles time ratio time response time responses time scale time scale of displacement time window time-dependent inhibitor time-inr determinations times increase times maximum times uln timing of drug administration tissue damage tissue quinolone concentrations tissues of mice tissues of rats tnf antagonist tnf antagonists tnf-blocking agent tnf-blocking agents tnfa-blocking agents tobacco products tolbutamide plasma levels tolbutamides conversion tolerability profile tolerance development tolerant patients tonic convulsion topical dose topical drugs topical formulations topical glaucoma drugs topical medications topical products topical solution topical-injectable-implantable-insertable hormonal birth control products topo drugs topoisomerase activity level topoisomerase quantity topoisomerase-targeted chemotherapy toradol iv-im toradol oral toradol therapy torsades de pointe torsades de pointes torsades de pointes-type ventricular tachycardia tosylate injection total auc total gsh total rna toxic action toxic concentrations toxic drug toxic effects toxic epidermal necrolysis toxic levels toxic medications toxic metabolites toxic neurological effects toxic pathway toxic product toxic reactions toxicity brain hemorrhage toxicity characteristics toxicity investigation toxicity of bupropion toxicity of cadmium toxicity of drugs toxicity of filipin toxicity of flucytosine toxicity of methotrexate toxicity of salicylates toxicity study toxicity tests toxicodynamic interference toxicokinetic interferences toxicologic profile toxicology screen toxicology study toxin molecules toxin serotypes trace elements tract antibacterial tract infections tract obstruction traction of drug traditional agents training dose training-induced neurobiological alterations tranexamic acid trans-placental passage transaminase levels transcriptase inhibitor transcriptase inhibitors transcriptase inhibitors didanosine transcription factor iegs transcriptional activator transcriptional regulation transdermal fentanyl transdermal nitroglycerin transdermal system transferase enzyme activity transferase level transfusion practices transient asymptomatic liver enzyme elevations transient cardiac arrhythmias transient delirium transient dose-dependent increase transient drowsiness transient hypotensive response transient increase transient outward rectification transient peak plasma concentrations transient thrombocytopenia transit time transit-enhancing effect transit-enhancing effect of dmpge transition metal cations transition metals translocating action transplant patients transport of digoxin transport of methotrexate transport of noradrenaline storage vesicles transport pathway transport ratio transport system transport systems lapatinib transport-related effects transporter p-glycoprotein transporter systems tranxene tablets tranylcypromine sulfate traumatic edemas trazodone hydrochloride treated animals treated patients treated with appropriate dosage adjustment treatment arm treatment cessation treatment control treatment costs treatment costs of schizophrenia treatment discontinuation treatment groups treatment measures treatment of angina treatment of anticholinesterase poisoning treatment of convulsions treatment of depression treatment of drug treatment of erection disorders treatment of ewes treatment of heroin addiction treatment of hypotension treatment of osteoarthritis treatment of patients treatment of poisoning treatment of toxin treatment of trypanosomiasis treatment outcome treatment period treatment periods treatment plans treatment practices treatment regimen treatment response treatment study treatment-emergent positive bivalirudin antibody tests treatment-experienced patients treatment-naive patients treatment-related pattern treatment-resistant schizophrenia treatments of magnesium depletion triacylglycerol synthesis trial data trials database trials of chloral hydrate trials of drug interactions trials of grepafloxacin triazolam contraindicated triazolam elc triazolam gi motility agents triazole antifungals triclofos sodium tricyclic amphetamines tricyclic anti-depressants tricyclic antidepressant agent tricyclic antidepressant assay tricyclic antidepressant class tricyclic antidepressant desipramine tricyclic antidepressant imipramine tricyclic antidepressant level tricyclic antidepressant levels tricyclic antidepressants experienced tremor triglyceride levels triglyceride plasma levels triiodothyronine levels trileptal aed co-administered dose trileptal dose trileptal doses trimethyl lead triphosphate metabolite triple-immunosuppression regimens triple-therapy regimens tromethamine protein binding trophoblastic disease trough citalopram plasma levels trough concentration trough concentrations trough concentrations of bosentan trough concentrations of digoxin trough cyclosporine concentrations trough plasma carbamazepine trough plasma concentrations trough plasma enoxacin levels trough serum level trough serum valproic acid concentrations true concentration true decrease true drug interaction true values tsh levels tsh secretion tuberculosis andusing tubular atrophy tubular excretion tubular organic cation transport tubular transport tumorigenic alterations tumour cell tumour cell resistance tumour cells tumour phenotype tumour response tumour total nitrosourea peak concentrations tumour type tumour vascularity tumour virus gene expression tumour virus promoter twelve healthy male volunteers twelve strains twenty four male wistar rats twenty-four healthy male subjects twice-a-day administration twitch strength two drugs can lead two hour period two-fold increase two-fold increases two-hour period two-lever drug discrimination two-period crossover study two-second increase two-way crossover study two-way interaction two-year carcinogenesis study twofold greater antitumour activity twofold increase type ii diabetic patient type ii pyrethroid type strain type strain of enterococci type strains type-specific differences typhoid vaccines tyrosine phosphorylation tyrosine phosphorylation status tysabri clearance tysabri dose udp-glucuronidation enzymes udp-glucuronyltransferase level ugt enzymes ulcer site ulcerans infection ulcerative colitis ulcerogenic effect ultimate effect ultimate prothrombin effect ultimately atherosclerotic cardiovascular disease unbound drug unbound fosinoprilat unbound fraction unbound ketorolac plasma levels unbound valproate uncertain mechanism uncomplicated hypertension uncomplicated urinary tract infections uncompromised elderly patients unconjugated nacmc uncontrolled data uncontrolled diabetes uncontrolled domestic uncontrolled study undergoing strenuous physical activity underlying disease underlying mechanism understanding of drug side effects understanding of pain mechanisms undesirable effects undetectable insulin release undetectable levels unexpected adverse effects unexpected adverse reactions unexpected hypotension unexpectedly high plasma levels unexpectedly low serum concentrations unexplored area unfractionated heparin uninfected volunteers unintentional sinequan overdosage unique biopharmaceutical properties unmodified nacmc unpredictable potentiation unprotected sexual intercourse unrecognized interaction unrecognized interactions unreliable prothrombin time determinations unsatisfactory lipid response unsteady gait untreated hypothyroidism unwanted effects updated review upper gastrointestinal adverse events upper gastrointestinal adverse experiences upper gastrointestinal bleeding upper gastrointestinal events uptake inhibitors cocaine uptake of norepinephrine uptake of sodium iodide uptake sites uremic patients uric acid uric acid excretion uric acid level uric acid levels uricosuric agents uricosuric drugs uricosuric medication uridine glucuronosyltransferase urinary acidifying agents urinary alkalinizers urinary alkalinizing agents urinary antiseptic effect urinary assays urinary bilirubin urinary catecholamine levels urinary catecholamines urinary frequency urinary homocysteine urinary laboratory tests urinary levels urinary output urinary potassium urinary protein urinary recovery urinary steroid determinations urinary thioether assay asa method urinary tract urinary tract antibacterial urinary tract infections urinary tract obstruction urinary uric acid excretion urinary values urine creatinine urine creatinine levels urine flow urine glucose levels urine ketone test urine levels urine levels of norfloxacin urine protein urine red-orange urine samples urine sampling urine test urine volume urologic surgery us food use younger patients used with caution useof rifampicin users of sildenafil ussing-type chamber uterine fibroids uterine hypertonus uterine rupture utero exposure utilization of digitoxin vaccines neurological complications vaginal bleeding vaiproic acid valdecoxib coadministration valdecoxib metabolism valdecoxib pharmacokinetics valdecoxib steadystate plasma concentrations valid prothrombin time validation of method valproate cmin valproate cmin concentrations valproate concentration valproate concentrations valproate keppra valproate plasma concentration valproic acid concentrations valproic acid diminished binding valproic acid-phenobarbital value of serum vana antisense rna effect vancomycin resistance vancomycin resistance reversal vancomycin susceptibility vancomycin-flavone combinations vancomycin-resistant strains vancomycin-sensitive strains vanh promoter-vana antisense gene cassette vanillylmandelic acid vardenafil auc vardenafil bioavailability vardenafil clearance vardenafil cmax vardenafil concentration vardenafil dose vardenafil half-life vardenafil metabolite vardenafil plasma levels vardenafil vardenafil concentration variability component variability of effect variable degrees variable effects variable elevations variable half-life variables of digoxin various ca vas deferens vascular dilation vascular lesions vascular rejection vascular resistance vascular response vascular tone vasoactive drugs vasoconstricting agents vasoconstrictive action vasoconstrictive nasal drops vasoconstrictor drugs vasoconstrictor thromboxane vasodilating effects vasodilating property vasodilator activity vasodilator effects vasodilator properties vasopressor drugs vasospastic effects vecuronium-induced neuromuscular block velcade treatment venous pressure ventral tubercle ventricular arrhythmia ventricular cardiac preparations ventricular dysfunction ventricular failure ventricular fibrillation ventricular fibrulation ventricular function ventricular hypokinesia verapamil administration verapamil hydrochloride verapamil type vesselinovitch etal viable counts videx chewable-buffered tablets videx chewable-dispersible buffered tablets videx therapy vigorous physical activity vii antigen vii-x complex viii antigen viii coagulant activity vioxx therapy viracept antiarrhythmics viracept antimycobacterial agents viral loads virologic response virologic response rates virus gene expression virus promoter virus vaccine virus-positive patients vistide infusion visual analogue scales visual cortex vital sign monitoring vitamin k-dependent vitamin supplements vitamin-d-mediated signalling vitrasert implant vitro activity vitro anti-cryptosporidial activity vitro antiviral activity vitro aspirin-mediated inhibition vitro chromosomal aberration assay vitro concentrations vitro cytogenetics study vitro displacement vitro drug interaction vitro drug metabolism vitro effect vitro evaluation vitro excystment vitro excystment rates vitro experiments vitro finding vitro glucuronidation vitro human liver microsome vitro inhibitor vitro interaction vitro interaction of prostaglandin vitro metabolism vitro metabolism of tolbutamide vitro studies of alprazolam vitro studies of benzodiazepines vitro studies of iloprost vitro study vitro tests vivo animal vivo animal models vivo clinically vivo data vivo drug interaction vivo drug-drug interaction vivo drug-drug interactions vivo effects vivo evidence vivo experiments vivo interaction vivo interaction study vivo metabolic probe study vivo micronucleus test vivo platelet aggregation vivo rodent study denileukin diftitox vivo tests volatile agent volatile agents volatile anesthetic agents volatile inhalation anesthetics voltage-dependent ca volume depletion volume expansion volume-depleted patients volunteers loratadine descarboethoxyloratadine erythromycin voriconazole established drug interactions wallerian degeneration warfarin administration warfarin anticoagulants warfarin dose warfarin enantiomer pharmacokinetics warfarin interactions warfarin keppra warfarin levels warfarin metabolism warfarin pharmacokinetics warfarin plasma concentrations warfarin plasma levels warfarin potential effect warfarin requirement warfarin requirements warfarin sodium warfarin sodium overdosage warfarin sodium under-dosage warfarin study warfarin therapy warfarin treatment warfarin type warfarin wshow warfarin-type anticoagulant therapy warfarin-type anticoagulants warning coadministration warning potential warning signs warnings congestive heart failure warrants consideration washout phase waste incineration water pill watery stool wax matrix weakness hyperreflexia wedge pressure week course of cimetidine weeklong study weeks of rifabutin weeks of therapy weight heparins weighted least squares approach weightloss medications well-controlled clinical trial well-controlled clinical trials well-controlled patients well-controlled study well-defined pharmacokinetic-pharmacodynamic relationship wellbutrin tablets whelk nucella lapillus which enbrel white female volunteers white male rats whole-cell recording whole-cell recording technique whom nifedipine whose absorption wide distribution wide interindividual variability widespread effects wild-type alleles with appropriate dosage adjustment with tricor world health organization criteria world medical literature worsened glucose control wyeth-ayerst laboratories x-ray diffraction xanax dose reduction xanthine bronchodilators xanthine derivatives xanthine oxidase xanthine-derived adenosine antagonists xenobiotic metabolism xi assays yeast cell growth york heart association functional class younger patients zalcitabine activity zalcitabine phosphorylation zalcitabine triphosphate metabolite zaleplon accounts zaleplon cmax zaleplon dose zaleplon metabolism zevalin therapeutic regimen zidovudine ribavirin zidovudine study zidovudine tmax zimelidine etomidate antagonism opioid analgesics zinc chelation zinc insulin preparations zinc supplements zinc-chelating chromatography zn-sepharose gel zopiclone exposure